Adlina EM 25/5mg Tablet is used for the treatment of Type 2 diabetes mellitus in adults.
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Empagliflozin+Linagliptin is a combination medication belonging to the anti-diabetic class. It's utilized primarily for treating Type 2 diabetes, a condition marked by elevated blood glucose levels. This chronic condition necessitates lifestyle changes, medication, and regular check-ups.
Containing Empagliflozin and Linagliptin (25mg+5mg), this medication is employed alongside a proper diet and exercise regimen to manage high blood sugar in Type 2 diabetes patients. Adequate control of blood sugar helps prevent complications such as kidney damage, vision problems, nerve issues, limb loss, and sexual function impairment. Managing diabetes well can also lower the risk of heart attacks or strokes. Empagliflozin enhances sugar removal by the kidneys, while Linagliptin raises levels of natural substances called incretins. Incretins aid in controlling blood sugar by boosting insulin release, particularly after meals, and reducing liver sugar production.
Administer this medication orally with or without food, usually once daily in the morning, as directed by your doctor. Dosage is determined by your medical condition and response to treatment. Consistently using this medication will yield the best outcomes. To help remember, take it at the same time each day. If your condition doesn't improve or worsens, promptly consult your doctor. Some common side effects may include frequent urination, dizziness, or light-headedness. To mitigate dizziness, rise slowly when getting up from sitting or lying positions. While most side effects are temporary, consult your doctor if they persist.
Prior to taking this medication, inform your doctor of allergies to empagliflozin, linagliptin, or any other allergens. Inactive ingredients in the product can trigger allergic reactions or other complications. Refrain from abruptly stopping Empagliflozin+Linagliptin even if you feel better, as blood sugar levels fluctuate. Abrupt discontinuation could heighten the risk of complications like vision loss, kidney problems, and nerve damage. This medication is unsuitable for Type 1 diabetes or severe kidney/liver disease. During pregnancy or lactation, discuss usage with your doctor, weighing potential risks and benefits.
Refrain from alcohol consumption while on Adlina EM 25/5mg Tablet, as it may heighten the risk of adverse effects.
The effects of Adlina EM 25/5mg Tablet on unborn babies are unknown. Hence, its use during pregnancy is not advised unless recommended by your doctor.
It is uncertain whether Adlina EM 25/5mg Tablet passes into breast milk. Therefore, it should only be used during breastfeeding if deemed necessary by a physician.
Adlina EM 25/5mg Tablet generally does not impact your ability to drive or operate heavy machinery. However, avoid such activities if the medication affects your capabilities.
Exercise caution if you have significant kidney issues when taking Adlina EM 25/5mg Tablet. Consult your doctor before using it.
Adlina EM 25/5mg Tablet is not recommended for individuals with severe liver problems. Prior consultation with your doctor is advised.
Empagliflozin works by inhibiting a protein in the kidneys called sodium-glucose co-transporter 2 (SGLT-2). This action prevents the kidneys from reabsorbing glucose (sugar), leading to the elimination of excess blood sugar through urine.
Linagliptin functions by blocking another protein known as dipeptidyl-peptidase 4 (DPP-4). This inhibition prompts the pancreas to release more insulin in response to elevated blood sugar levels, particularly after meals. Consequently, the combination of Empagliflozin and Linagliptin in Adlina EM 25/5mg Tablet helps lower and maintain blood sugar levels within a suitable range.
Urinary tract infection, Hypoglycemia (low blood glucose level), Cough, Nasopharyngitis (inflammation of the throat and nasal passages), Nausea, Vomiting, Constipation, Genital fungal infection
Type 2 diabetes is a chronic condition that disrupts the body's ability to properly use insulin, a hormone crucial for regulating blood sugar levels. In this type of diabetes, either the body doesn't produce enough insulin or it becomes resistant to the effects of insulin. Typically, middle-aged or older individuals are at a higher risk of developing type 2 diabetes, which was formerly referred to as adult-onset diabetes.
Symptoms of type 2 diabetes encompass increased thirst, frequent nighttime urination, slow healing of wounds, heightened hunger, fatigue, and blurred vision. Weight gain is common in some cases, while weight loss might occur more rarely. Complications of type 2 diabetes can involve nerve problems (neuropathy), kidney issues (nephropathy), and damage to the retina of the eyes (retinopathy) leading to potential blindness, limb loss, sexual dysfunction, and an elevated risk of heart attacks or strokes. This chronic condition requires careful management to maintain optimal health and prevent potential complications.
Empagliflozin: This medication targets the sodium-glucose co-transporter 2 (SGLT2), a crucial transporter responsible for reclaiming glucose from the filtered blood back into circulation. Empagliflozin inhibits SGLT2, reducing the reabsorption of glucose in the kidneys. This action lowers the renal threshold for glucose, leading to increased urinary glucose excretion.
Linagliptin: A DPP-4 inhibitor, Linagliptin targets an enzyme that breaks down incretin hormones, specifically glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). Linagliptin boosts active incretin hormone levels, stimulating insulin release in response to glucose levels. Additionally, it curbs glucagon secretion, thereby reducing hepatic glucose output. GLP-1 and GIP regulate glucose balance, with their levels rising post-meal.
For Linagliptin, a 5mg dose is taken daily. If combined with metformin, maintain the metformin dose and administer Linagliptin concurrently. Combining Linagliptin with sulphonylurea or insulin may require a lower dose of these to minimize hypoglycemia risk. Patients with renal impairment need no Linagliptin dose adjustment. Studies suggest hepatic impairment may not warrant dose adjustment, but cautious use is advised. In elderly patients, no dose change based on age is necessary, though caution is urged for those above 80 years.
Linagliptin can be taken with or without meals at any time. Missed doses should be taken as soon as remembered; however, a double dose on the same day should be avoided.
Drug interactions can vary from person to person, so it's crucial to consult your doctor before starting any medication. Here are some interactions and precautions related to Adlina EM 25/5mg Tablet:
Interaction with Alcohol: Avoid alcohol consumption while taking Adlina EM 25/5mg Tablet, as it could lead to changes in blood sugar levels.
Interaction with Medicine: There can be interactions with various medicines, including Aripiprazole, Clozapine, Dexamethasone, Gatifloxacin, and Bexarotene. Discuss with your doctor if you are taking any of these medicines along with Adlina EM 25/5mg tablet.
Disease Interactions:
Hypersensitivity to the active substance or to any of the excipients.
Limited information is available regarding the impact of Adlina EM 25/5mg Tablet on pregnant and breastfeeding women. It is recommended to avoid the use of Adlina EM 25/5mg Tablet during both pregnancy and breastfeeding. Since the effects of the medication on these specific populations are not well understood, it's best to consult your doctor for guidance before using Adlina EM 25/5mg Tablet if you are pregnant or breastfeeding. Your doctor can weigh the potential benefits and risks and help you make an informed decision about the use of the medication.
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