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Zepatid 7.5 Prefilled Syringe For Subcutaneous Use
Zepatid is prescribed alongside proper diet and physical activity to enhance blood sugar control in adults with type 2 diabetes.
- Not recommended for individuals with a history of pancreatitis.
- Not approved for treating type 1 diabetes.
- Always take medication following the advice of a registered physician.
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✅ Description:
Tirzepatide acts on both GIP and GLP-1 receptors. It is a synthetic 39-amino-acid peptide with a C20 fatty diacid chain, which helps it bind to albumin and extend its half-life. By activating these receptors, tirzepatide increases insulin release and reduces glucagon levels, both of which depend on glucose levels.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Uses of Zepatid
- To improve glycemic control in adults with Type 2 diabetes mellitus
- Management of Obesity
✔️ Dosage & Administration of Zepatid
- Route: Subcutaneous injection only.
- Initiation Dose: 2.5 mg once weekly (not for glycemic control, only for initiation).
- After 4 Weeks: Increase to 5 mg once weekly.
- Further Adjustments: Can be raised in 2.5 mg steps after 4-week intervals if needed.
- Maximum Dose: 15 mg once weekly.
Missed Dose:
- Take within 4 days of the missed dose.
- If more than 4 days pass, skip it and resume the regular schedule.
Injection Guidelines:
- Inject into the abdomen, thigh, or upper arm; rotate sites.
- Can be taken with or without meals, any time of day.
- If used with insulin, inject separately in different spots, but same region is acceptable.
Handling Instructions:
- Do not freeze or expose to light.
- Do not use if frozen or discolored.
- Do not mix with other solutions or medications.
- The needle cap contains natural rubber (latex derivative) and may cause allergic reactions.
✔️ Side Effects of Zepatid
- Nausea
- Diarrhea
- Vomiting
- Constipation
- Indigestion
- Reduced appetite
- Abdominal pain
✔️ Interaction
- May slow stomach emptying, affecting absorption of oral drugs.
- Monitor patients using drugs with narrow therapeutic windows (e.g., warfarin).
- Dose adjustments may be needed when taken with insulin or sulfonylureas to prevent hypoglycemia.
- Women on oral contraceptives should use non-oral or barrier methods during the first 4 weeks of therapy and 4 weeks after each dose increase.
✔️ Contraindications
- Known allergy to tirzepatide or any ingredients in Zepatid.
- History (personal or family) of medullary thyroid cancer or MEN 2 syndrome.
✔️ Pregnancy & Lactation
Use only if the benefit justifies potential risks to the fetus. Consider both maternal health needs and potential risks to a nursing child when used during breastfeeding.
✔️ Precautions & Warnings
- Inform patients about possible thyroid tumors (MTC).
- Monitor for signs of pancreatitis and discontinue if suspected.
- Adjust insulin or sulfonylurea dose to lower risk of hypoglycemia.
- In renal impairment with GI symptoms, monitor kidney function closely.
- Watch for progression of diabetic retinopathy.
- Evaluate gallbladder health if symptoms of gallstones appear.
- Discontinue and treat if allergic reactions occur.
✔️ Storage
- Store between 2°C and 8°C (refrigerated).
- Do not freeze.
- Protect from light.
- Keep away from children.
- Dispense only with a valid prescription.
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