Montene 10mg Tablet

Uses of Montene 10mg Tablet

• Asthma
• Seasonal Allergies

How does Montene 10mg Tablet work?

Montene 10mg Tablet containing montelukast works by opposing the actions of Leukotrienes. Leukotrienes cause narrowing and swelling of airways in the lungs and also cause allergy symptoms. By blocking leukotrienes, Montelukast improves asthma symptoms, helps control asthma, and improves seasonal allergy symptoms.

Side Effects of Montene 10mg Tablet

• Diarrhea
• Dizziness
• Headache
• Abdominal cramp
• Flu-like symptoms
• Body aches or Pain
• Pus in urine
• Agitation and anxiety
• Skin rash
• Heartburn
• Blurred vision
• Infection of the airways
• Swelling of face, lips, eyelids, tongue, hands and feet
• Nausea or Vomiting
• Nausea
• Vomiting

Quick Suggestions:

• Montene 10mg Tablet is prescribed for asthma prevention and the treatment of allergy symptoms like sneezing and runny nose.
• It is generally safe with minimal side effects.
• Take it 2 hours before exercising if you have exercise-induced asthma.
• It does not provide immediate relief during sudden breathing problems. For acute symptoms, use a rescue inhaler as prescribed.
• Do not stop using Montene 10mg Tablet without consulting your doctor, even if you feel better.
• If you have phenylketonuria, be aware that chewable tablets may contain aspartame, which is not recommended in this condition
• Anti-inflammatory compounds in ginger can help relax airway membranes, potentially reducing coughing.
• Stress can weaken the immune system, increasing the risk of illness. Managing stress through regular exercise, meditation, deep breathing, and relaxation techniques can help maintain a healthy immune system.
• Aim to get 7-9 hours of sleep each night to support overall health and immune function.
• Minimize contact with known allergens such as pollen and dust. Identify any food items that may cause allergies for you and avoid them.
• Personal hygiene and cleanliness: Maintain good personal hygiene practices and keep your surroundings clean to reduce the risk of respiratory infections.
• Adequate hydration is important for respiratory health. Drinking liquids at room temperature can help alleviate cough, runny nose, and sneezing.

Indication

Montelukast is used to treat and prevent asthma. It will decrease the symptoms and the number of acute asthma attacks. However, this medicine should not be used to relieve an asthma attack that has already started. This medicine is also used to prevent exercise-induced bronchoconstriction (EIB) and treat symptoms of allergic rhinitis (hay fever), including seasonal (short-term) or perennial (long-term) allergic rhinitides, such as sneezing, runny nose, itching, or wheezing. This medicine is available only with your doctor's prescription.

This product is available in the following dosage forms:

• Tablet
• Tablet, Chewable

Pharmacology

Montelukast is an orally active, selective leukotriene receptor antagonist that blocks the cysteinyl leukotriene receptor (CysLT1). The cysteinyl leukotrienes (LTC4, LTD4, LTE4) are arachidonic acid metabolic products that are produced by a variety of cells, including mast cells and eosinophils. Cysteinyl leukotrienes and leukotriene receptor occupancy have been linked to the pathophysiology of asthma and allergic rhinitis, such as airway edema, smooth muscle contraction, and altered cellular activity associated with the inflammatory process, all of which contribute to asthma symptoms.

Dosage & Administration of Montene 10mg Tablet

Adult Dose:

• Chronic asthma: For adults with chronic asthma, the recommended dose is 10 mg of the film-coated tablet taken once daily in the evening.
• Allergic rhinitis: Adults with allergic rhinitis should take 10 mg once daily.
• Prophylaxis of exercise-induced asthma: Adults should take 10 mg at least 2 hours prior to exercise. Additional doses should not be taken within 24 hours.
• Elderly: No dosage adjustment is needed for elderly patients.
• Hepatic impairment: For patients with mild to moderate hepatic impairment, no dosage adjustment is needed.

Child Dose:

• Asthma prophylaxis and maintenance treatment: The dosages for children vary depending on age groups:
  • <12 months: Safety and efficacy not established.
  • 12-24 months: 4 mg (granules) taken orally once daily in the evening.
  • 2-6 years: 4 mg (chewable tablet or granules) taken orally once daily in the evening.
  • 6-15 years: 5 mg (chewable tablet) taken orally once daily in the evening.

15 years: 10 mg (conventional tablet) taken orally once daily in the evening.

• Exercise-induced bronchospasm prophylaxis:
  • 6-15 years: 5 mg (chewable tablet) taken orally 2 hours before exercise. Additional doses should not be taken within 24 hours.

15 years: 10 mg taken orally 2 hours before exercise. Additional doses should not be taken within 24 hours. If the medication is taken for another indication, an additional dose should not be taken to prevent exercise-induced bronchospasm.

• Perennial allergic rhinitis:
  • <6 months: Safety and efficacy not established.
  • 6-24 months: 4 mg (granules) taken orally once daily.
  • 2-6 years: 4 mg (chewable tablet or granules) taken orally once daily.
  • 6-15 years: 5 mg (chewable tablet) taken orally once daily.

15 years: 10 mg (conventional tablet) taken orally once daily.

• Seasonal allergic rhinitis:
  • <2 years: Safety and efficacy not established.
  • 2-6 years: 5 mg (chewable tablet) or 4 mg (granules) taken orally once daily.
  • 6-15 years: 5 mg (chewable tablet) taken orally once daily.

15 years: 10 mg (conventional tablet) taken orally once daily.

Renal Dose:

• Renal impairment: No dosage adjustment is needed for patients with renal impairment.
• It is important to take the medication as advised by your physician. Swallow the medicine with a glass of water and do not crush or chew it. The appropriate dose and duration of treatment will be determined by your doctor based on your age, body weight, and medical condition.

Interaction

• The plasma concentration of the medication may be decreased when used together with potent inducers of cytochrome P450 isoenzymes, such as phenobarbital, phenytoin, and rifampicin. 
• When combined with theophylline, prednisone, prednisolone, terfenadine, digoxin, warfarin, gemfibrozil, itraconazole, thyroid hormones, sedative-hypnotics, nonsteroidal anti-inflammatory agents, benzodiazepines, decongestants, oral contraceptives, and cytochrome P450 (CYP) enzyme inducers, no dose adjustment is required.
• The medication's bioavailability and effectiveness are not significantly affected by food or other circumstances.

Contraindications

Montene 10 is not recommended for people who are allergic to any of its ingredients.

Pregnancy & Lactation

In pregnant women, there are no appropriate and well-controlled trials. Montelukast should only be taken during pregnancy if absolutely necessary. Montene 10 can be found in breast milk. When giving Montelukast to a nursing woman, extreme caution should be used.

Precautions & Warnings

• Allergy: Do not take Montene 10mg Tablet if you are allergic to Montene 10mg Tablet or any of its ingredients. It's important to check the ingredients list and consult with your healthcare provider if you have any known allergies.
• Mental disorders: Inform your doctor if you have any mental disorders before starting Montene 10mg Tablet. This medication has the potential to cause mood changes, including symptoms such as anxiety, aggressive behavior, irritability, restlessness, and sometimes depression. If you experience any of these symptoms, it is important to inform your doctor.
• Allergen avoidance: It is advised to avoid contact with known allergens, such as pollen and dust, to reduce the risk of triggering allergic reactions. Additionally, certain food items are known to cause allergies, so it's important to be aware of any specific allergens that may affect you.
• Alcohol and other antidepressants: Concurrent use of Montene 10mg Tablet with alcohol or other antidepressant medications should be avoided. Combining these substances may affect mental alertness and can have potential adverse effects.
• Do not stop abruptly: Even if you are asymptomatic and feel good, do not stop taking Montene 10mg tablet abruptly. Suddenly stopping the medication may lead to an acute attack of asthma. It is important to follow your doctor's instructions regarding the duration and discontinuation of the medication.

Storage Conditions

Store Montene 10mg Tablet at room temperature in a cool dry place. Keep it out of reach of children and pets.