Generic Name: Flunarizine 5mg
Manufacturer/Distributor: The Acme Laboratories Ltd.
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Indication
Pharmacology
Flunarizine is the cinnarizine difluorinated derivative. It is a selective calcium channel antagonist. By reducing excessive calcium transmembrane input, calcium transmembrane inflow is decreased. Flunarizine stops cells from having too much calcium. Normal calcium homeostasis in cells is unaffected. Additionally, flunarizine has relaxing and antihistaminic properties. It has a 99 percent affinity for plasma protein.
Dosage & Administration
Interaction
Galactorrhea has been recorded in a small number of women taking oral contraceptives during the first two months of treatment with Flunarizine. Carbamazepine and phenytoin, both hepatic enzyme inducers, may interact with flunarizine by increasing its metabolism. As a result, an increase in flunarizine dosage may be necessary.
Contraindications
Flunarizine hypersensitivity Flunarizine is not recommended for people who have had a depressive episode in the past, or who have symptoms of Parkinson's disease or other extrapyramidal illnesses.
Side Effects
Pregnancy & Lactation
There is no evidence of safety during pregnancy or lactation.
Precautions & Warnings
Flunarizine may cause sleepiness, which is exacerbated when combined with alcohol or other central nervous system depressants. When a patient's mental attention is lost, he or she should be warned not to drive or do other potentially dangerous jobs. Flunarizine is not recommended for migraine relief. As a result, there is no reason to increase the Flunarizine dosage. This medication may cause extrapyramidal and depressive symptoms, as well as reveal Parkinsonism in people who are predisposed to it, such as the elderly. Flunarizine should be used with caution in such patients.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
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