Marincal-D Tablet

✔️ Uses of Marincal-D Tablet

• Osteoporosis
• Osteomalacia (Rickets)
• Vitamin D deficiency
• Hypoparathyroidism
• Latent tetany

✔️ How does Marincal-D Tablet work?

Marincal-D Tablet consists of Calcium (mineral) and Cholecalciferol (Vitamin D3). Calcium is a mineral that is used to prevent or treat a calcium deficiency. It provides essential nutrients to maintain bone formation and maintenance. Cholecalciferol helps maintain blood calcium and phosphorus levels and mineralization of bone.

✔️ Side Effects of Marincal-D Tablet

Flatulence, diarrhea, constipation, upper GI discomfort, and other symptoms are unusual. Hypercalcemia as a result of prolonged use has only been observed in a few cases.

✔️ Quick Suggestions:

• Calcium is needed for healthy bones, muscles, nervous system, and heart
• Calcium can make the bones and teeth strong
• Vitamin D3 helps absorb calcium and other minerals in the body
• Include dairy products like milk, yogurt, cheese, or milk-based custard in your diet: Dairy products are excellent sources of calcium and other essential nutrients.
• Eat daily servings of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables: These vegetables are rich in vitamins, minerals, and dietary fiber.
• Include the best dietary sources of vitamin D: Fish liver oils and vitamin D-fortified milk are excellent sources of vitamin D, which is essential for calcium absorption and bone health.
• Snack on calcium-rich nuts like Brazil nuts or almonds: Nuts are not only a good source of calcium but also provide healthy fats and other beneficial nutrients.
• Sprinkle sesame seeds over your food, vegetables, and salads: Sesame seeds are high in calcium and can be a flavorful addition to your meals.
• Avoid or reduce the intake of caffeine, soft drinks, and alcohol: These substances can inhibit calcium absorption, so it's best to limit their consumption.
• Replace meat with tofu or tempeh for extra calcium: Tofu and tempeh are plant-based sources of calcium that can be used as alternatives to meat.
• If you are taking Marincal-D tablets, it is important to inform your doctor and laboratory staff before undergoing blood tests as it may interfere with cholesterol tests.
• Clinical monitoring of serum electrolyte concentrations and cardiac function is recommended when using Marincal-D Tablet. Regular check-ups and tests can help ensure the medication's safety and effectiveness.

✔️ Indication

• Marincal-D Tablet is used for the treatment of vitamin D and calcium deficiency.
• It is used for the treatment of osteoporosis or bone-related disorders.
• It is also used in special populations like the elderly, pregnant, and breastfeeding who need vitamin D and calcium supplements.

✔️ Pharmacology

Calcium and Vitamin D3 are commonly recommended together for maintaining healthy bones and supporting overall health. Coral Calcium, which is sourced from coral origin, is often promoted as a form of calcium supplementation. Proponents of coral calcium claim that it has a chemical structure similar to human bone composition, leading to improved absorption compared to other calcium sources. However, it's important to note that scientific evidence supporting these claims is limited.

While calcium carbonate is a common form of calcium supplementation, the specific source, such as coral calcium, may vary. It's always advisable to choose reputable brands and consult with a healthcare professional for personalized recommendations.

Vitamin D3, also known as cholecalciferol, plays a crucial role in calcium absorption and maintaining calcium balance in the body. It helps the gastrointestinal tract absorb calcium efficiently and aids in its utilization by various tissues, including bones. Adequate vitamin D levels are important for optimal bone health.

✔️ Dosage & Administration of Marincal-D Tablet

Take one tablet with plenty of water once or twice a day, or as prescribed by your doctor. Better absorption occurs when food is consumed on an empty stomach.

Remember, individual requirements for calcium and vitamin D may vary based on factors like age, sex, underlying health conditions, and lifestyle. Therefore, personalized guidance is essential for meeting your specific needs.

✔️ Interaction

Drug Interactions:

• High cholesterol drugs: Cholestyramine and colestipol may interact with Marincal-D Tablet. It is important to consult with your doctor regarding the timing and administration of these medications to avoid any potential interactions.
• Antibiotics: Drugs like doxycycline, ciprofloxacin, and penicillin may interact with Marincal-D Tablet. It's advisable to discuss the timing and potential adjustments with your healthcare professional.
• Anti-cancer drugs: Estramustine, an anti-cancer medication, may interact with Marincal-D Tablet Ensure to inform your doctor about all medications you are taking, including anti-cancer drugs.
• Drugs treating bone loss: Alendronate, a medication used to treat bone loss, may interact with Marincal-D Tablet. Your healthcare provider can guide you on the appropriate timing and administration of these medications.
• Thyroid hormone: Levothyroxine, a thyroid hormone replacement medication, may interact with Marincal-D Tablet. Your doctor can provide guidance on how to manage these medications together.
• Weight-loss drugs: Orlistat, a weight-loss medication, may interact with Marincal-D tablets. Discuss the use of these medications with your healthcare professional.
• Seizure medications: Phenobarbital, a medication used to treat seizures, may interact with Marincal-D tablets. Your doctor can advise on managing these medications together.
• Other medications: Mineral oils (paraffin), water pills (furosemide), and heart-related medicines (digitoxin) may also interact with Marincal-D Tablet. It's essential to inform your healthcare provider about all the medications you are taking to ensure their safe and effective use.

Food Interactions:

• It is advisable to avoid or reduce the intake of caffeine, soft drinks, and alcohol while using Marincal-D tablets, as they can inhibit calcium absorption. This is particularly important if you are aiming to optimize calcium absorption and maintain bone health.

Disease Interactions:

• Prior to using Marincal-D Tablet, it is crucial to consult with your doctor if you have certain medical conditions such as hypercalcemia (high blood calcium levels), hypervitaminosis D (excess vitamin D), malabsorption syndrome, vitamin D toxicity, heart disease, kidney disease, liver disease, blood vessel diseases, kidney stones, sarcoidosis, Crohn's disease, Whipple's disease, achlorhydria (low stomach acid), low levels of bile, phosphate imbalance, diabetes, or phenylketonuria (PKU). Your doctor will consider these conditions and may adjust the dosage or monitor your health closely while using this medication.

✔️ Contraindications

• Hypersensitivity: If you have a known hypersensitivity or allergy to any of the components of Marincal-D Tablet, it is important to avoid its use.
• Hypocalcemia from Vitamin D3 Overdose: Marincal-D Tablet should not be used if you have hypocalcemia (low blood calcium levels) resulting from an overdose of vitamin D3. In this case, alternative treatment options should be considered.
• Hyperparathyroidism: Hyperparathyroidism is a condition characterized by excessive production of parathyroid hormone, which can lead to high blood calcium levels. Marincal-D Tablets are not recommended in individuals with hyperparathyroidism.
• Bone Metastases: Marincal-D Tablet is contraindicated in individuals with bone metastases, which refers to cancer that has spread to the bones. Alternative treatment options should be explored.
• Severe Renal Insufficiency: Individuals with severe renal (kidney) insufficiency should avoid using Marincal-D Tablet. Impaired kidney function can affect the body's ability to process and excrete calcium properly.
• Severe Hypercalciuria: Severe hypercalciuria, which refers to excessive urinary excretion of calcium, is a contraindication for the use of a Marincal-D Tablet. Consult with a healthcare professional for appropriate management options.
• Renal Calculi: If you have a history of renal calculi (kidney stones), it is important to avoid the use of a Marincal-D Tablet, as it can potentially exacerbate the condition.

✔️ Pregnancy & Lactation

If a doctor specifically recommends Marincal-D Tablet for pregnant and lactating mothers, it indicates that the potential benefits of using the medication outweigh the potential risks. In such cases, it is important to follow the doctor's advice and instructions regarding dosage, duration, and any specific precautions to be taken.

During pregnancy and lactation, maintaining adequate calcium and vitamin D levels is important for the mother's health as well as the proper development of the baby. Calcium is essential for the development of the baby's bones, teeth, and overall growth. Vitamin D helps with the absorption of calcium and supports various bodily functions.

However, it's crucial to note that individual circumstances may vary, and the decision to use any medication during pregnancy or lactation should always be made in consultation with a healthcare professional. They will consider the specific needs, potential risks, and benefits for the mother and baby based on the available evidence and the individual's health condition.

It's advisable for pregnant and lactating women to consult with their obstetrician-gynecologist or healthcare provider who can provide personalized recommendations and closely monitor their health throughout the process.

Remember, every medication should be used under medical supervision, and it's important to communicate openly with your healthcare professional regarding any concerns or questions you may have.

✔️ Precaution & Warnings:

Allergy and Inactive Components: Inform your doctor if you are allergic to Marincal-D Tablet or any of its inactive components. This is important to ensure your safety and prevent any potential allergic reactions.

Contraindications:

• Hypercalcemia: Marincal-D Tablet is not recommended if you have high levels of calcium in your blood.
• Hypervitaminosis D: It is not advisable to use Marincal-D Tablet if you have excessive levels of vitamin D.
• Malabsorption syndrome: If you have difficulty absorbing nutrition from food due to malabsorption syndrome, Marincal-D Tablet may not be suitable for you. Consult your doctor for alternative options.

Medical History:

• Inform your doctor about any history of heart disease, kidney disease, liver disease, blood vessel diseases, kidney stones, sarcoidosis, Crohn's disease, Whipple's disease, achlorhydria (low stomach acid), low levels of bile, or phosphate imbalance. These conditions may require special considerations or monitoring while using Marincal-D Tablet.

Pregnancy and Breastfeeding:

• If you are pregnant or breastfeeding, it is important to consult with your doctor before using Marincal-D Tablet. They will evaluate the potential risks and benefits for you and your baby.

Alcohol Intake:

• Limit alcohol intake while using Marincal-D Tablet, as alcohol consumption may affect calcium absorption.

Use in Children:

• Marincal-D tablets can be used in children when advised by a doctor. Follow the doctor's instructions and dosage recommendations.

✔️ Storage Conditions

• Store Marincal-D Tablet in a cool and dry place, protected from direct sunlight, moisture, and heat.
• Keep it away from children and pets.