Halotaz Lotion 45gm Tube

✔️ Uses of Halotaz Lotion

Treatment of plaque psoriasis in adults.

✔️ Composition of Halotaz Lotion

Halobetasol Propionate 0.01% + Tazarotene 0.045%

✔️ How does Halotaz Lotion work?

Halobetasol propionate works by acting inside skin cells and inhibiting the release of certain chemical messengers in the body that cause redness, itching, and swelling. 

Tazarotene belongs to the class of ‘retinoids’. It is used to treat psoriasis. Retinoids are derived from vitamin A (retinol) and have anti-inflammatory and antiproliferative (reduces rapid skin cell division) action. Tazarotene works by slowing down the progression of the diseases. It can treat severe or extensive skin problems where the skin has become thick and scaly such as psoriasis. 

✔️ Adverse Effects of Halotaz Lotion

• Common: Redness, itching, swelling, burning, stinging, folliculitis, skin atrophy, peeling, and rash.
• Rare: Skin ulcers, increased eye pressure, photosensitivity, and skin discoloration.

✔️ Word of Advice: Halotaz Lotion

• Do not cover the area being treated with airtight dressings like bandages unless ordered by a doctor, as this may enhance the risk of side effects.
• Consult your doctor if your skin condition has not improved after 2 weeks of treatment.
• Do not use it more often or for longer than advised by your doctor.
• If you think the area of skin you are treating has become infected you should stop using Halotaz Lotion and consult your doctor.

✔️ Indication: Halotaz Lotion

Halotaz Lotion is a combination product used to treat a certain skin condition (psoriasis). It contains 2 ingredients: halobetasol and tazarotene. Halobetasol is a very strong (super-high potency) corticosteroid. It helps reduce the itching, redness, scaling, and swelling that can occur with this condition. Tazarotene is a retinoid product that works by affecting the growth of skin cells.

✔️ Pharmacology

• Halobetasol Propionate: A potent corticosteroid involved in cellular signaling, immune function, inflammation, and protein regulation. The precise mechanism for treating plaque psoriasis is not fully known.
• Tazarotene: A retinoid prodrug that is converted into tazarotenic acid. It binds to retinoic acid receptors (RARα, RARβ, RARγ) and may influence gene expression, though its exact role in plaque psoriasis treatment is uncertain.

✔️ Dosage & Administration: Halotaz Lotion

• Apply a thin layer once daily to cover the affected areas and rub gently.
• Ensure the skin is dry before applying the lotion, especially after a bath or shower.
• Do not exceed 50 g per week to avoid hypothalamic-pituitary-adrenal (HPA) axis suppression.
• Not for oral, ophthalmic, or intravaginal use.
• Safety and effectiveness in children and adolescents under 18 have not been established.

✔️ Interaction

• Avoid use with other corticosteroid products, whether oral or topical.
• No known food interactions.

✔️ Contraindications

Before taking Halotaz Lotion inform your doctor if you are allergic to Tazarotene or any ingredients present in it.

✔️ Pregnancy & Lactation

• Pregnancy: Contraindicated due to the presence of Tazarotene, a teratogenic substance.
• Lactation: No data on whether the drug or its metabolites are present in breast milk

✔️ Precautions & Warnings

• Pregnancy Risk: Due to the teratogenic nature of Tazarotene, ensure a negative pregnancy test before starting treatment. Women of reproductive potential should use effective contraception during treatment.
• HPA Axis Suppression: Prolonged use or use over large areas may lead to HPA axis suppression, with potential effects like Cushing’s syndrome, hyperglycemia, and glucosuria.
• Photosensitivity: The lotion increases sensitivity to sunlight; avoid sun exposure and extreme weather. Be cautious if the patient is taking photosensitizing drugs.
• Ophthalmic Effects: Prolonged use of topical corticosteroids may increase the risk of cataracts or glaucoma. Monitor visual symptoms and refer to an ophthalmologist if necessary.

✔️ Storage:

Store below 30°C, protected from light, and keep out of reach of children.