Tablet Manufacturer/Distributor: Beximco Pharmaceuticals Ltd. Generic Name: Lavocarnitine 330 mg Tablet
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Indications
Levocarnitine is shown in- Chronic Weariness Syndrome Heart Diseases Congestive Heart Failure Kidney Disease High Cholesterol Intermittent Claudication Dementia and memory impairment Down Syndrome Male infertility Hyperthyroidism
Pharmacology
Levocarnitine could be a normally happening substance required in mammalian vitality digestion system. It has been appeared to encourage long-chain greasy corrosive passage into cellular mitochondria, subsequently conveying substrate for oxidation and ensuing vitality generation. Greasy acids are utilized as an vitality substrate in all tissues but the brain. In skeletal and cardiac muscle, greasy acids are the most substrate for vitality generation.
Administration & Dosage
Levocarnitine tablet-
Adults: 330 mg two or three times daily. Depending on clinical response.
Infants and children: 50 to 100 mg/kg/day in divided doses, with a maximum of 3 g/day. Dosage should begin at 50 mg/kg/day. The exact dosage will depend on clinical response.
Levocarnitine solution (For oral use only. Not for parenteral use)-
Adults: The recommended dosage of Levocarnitine 100 ml solution is 10 to 30 ml/day. Higher doses should be administered with caution. Dosage should be started at 10 ml/day and be increased slowly while assessing tolerance and therapeutic response.
Infants and children: The recommended dosage of Levocarnitine 100 ml solution is 50 to 100 mg/kg/day. Dosage should be started at 50 mg/kg/day and be increased slowly to a maximum of 30 ml. /day. Levocarnitine oral solution can be given from 2-spoonful to 6-spoonful in divided dose as directed by physicians. Higher doses should be administered with caution.
Note: Levocarnitine 100 ml solution may be consumed alone or dissolved in drink or other liquid food. Doses should be spaced evenly throughout the day preferably during or following meals and should be consumed slowly in order to maximize tolerance.
Interaction
For the most part, Levocarnitine is well endured. Be that as it may, few side impacts counting temporal queasiness and heaving, stomach spasms, and the runs may happen.
Contraindications
Escitalopram is not recommended for patients who have a known hypersensitivity to Escitalopram, Citalopram, or any of the drug's inactive ingredients. It's not a good idea to take escitalopram and monoamine oxidase/pimozide at the same time.
Side Effect
Generally, Levocarnitine is well tolerated. However, few side effects including transient nausea and vomiting, abdominal cramps, and diarrhoea may occur.
Pregnancy & Lactation
There's no satisfactory and well-controlled considers in pregnant ladies. This sedate ought to be utilized amid pregnancy as it were in case clearly required. Levocarnitine supplementation in nursing moms has not been particularly examined. In nursing moms getting levocarnitine, any dangers to the child of excess carnitine intake have to be be weighed against the benefits of levocarnitine supplementation to the mother. Thought may be given to cessation of nursing or of levocarnitine treatment.
Precautions & Warnings
Gastrointestinal responses may result from a as well quick utilization of Levocarnitine. The security and viability of verbal levocarnitine has not been assessed in patients with renal lacking. Persistent organization of tall measurements of verbal levocarnitine in patients with extremely compromised renal work or in ESRD patients on dialysis may result in amassing of the possibly poisonous metabolites, trimethylamine (TMA) and trimethylamine-N oxide (TMAO), since these metabolites are ordinarily excreted within the pee.
Storage Conditions
Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.
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