Synogen 40mg Capsule

Uses of Synogen 40mg Capsule

• Joint pain & inflammation
• Osteoarthritis
• Rheumatoid arthritis
• Difficulties in flexibility & mobility
• Joint discomfort & stiffness (knee extension)
• Impaired joint function
• Strenuous exercise & sports related pain

How does Synogen 40mg Capsule work?

Synogen, which contains undenatured type II collagen, works by modulating the immune system and promoting joint health. Here's how it works:

Oral Tolerization: When Synogen, specifically undenatured type II collagen, is taken orally, it interacts with immune cells in the gut called Peyer's patches. These immune cells recognize specific epitopes present in the collagen.

Immune Response Modulation: The interaction between undenatured type II collagen and immune cells in the gut triggers a process known as oral tolerization. This process helps regulate the immune response and prevents the activation of destructive collagen-specific T-cells.

Suppression of Destructive T-cells: Collagen-specific T-cells are responsible for attacking and degrading collagen in the joints, leading to joint damage and inflammation. By suppressing the activation and release of these destructive T-cells, Synogen helps protect joint cartilage from degradation.

Reduction of Inflammation: Inflammation in the joints contributes to pain and stiffness associated with conditions like osteoarthritis. By modulating the immune response and suppressing destructive T-cell activity, Synogen helps reduce joint inflammation, providing relief from symptoms.

Joint Repair and Remodeling: As inflammation subsides and the destructive cycle is broken, the natural equilibrium of cartilage turnover shifts towards rebuilding and repair. This allows the joint cartilage to undergo the normal remodeling process, promoting joint health and function.

Overall, Synogen works by promoting oral tolerization, modulating the immune response, suppressing destructive T-cells, reducing joint inflammation, and supporting joint repair and remodeling.

Side Effects of Synogen 40mg Capsule

• Nausea
• Heartburn
• Diarrhoea
• Constipation
• Headache
• Allergic Skin Reaction
• Loss of appetite
• Bloating
• Flushing or redness of skin

Quick Suggestions:

• Weight plays a crucial role in the relationship between diet and osteoarthritis. Being overweight or obese puts additional strain on the joints, exacerbating symptoms. Excess body fat also contributes to inflammation, further worsening the condition. Losing weight has been shown to reduce pain, improve physical function, and enhance mobility.
• Engaging in appropriate exercise is beneficial for weight management and overall joint health. It helps increase joint flexibility, strengthen the muscles around the joints, and provide better support.
• Including one to two portions of oily fish in the weekly diet is recommended. If this is not feasible, taking a fish-oil supplement may be considered.
• Using mono-unsaturated oils such as rapeseed oil and olive oil is recommended.
• If blood cholesterol levels are high, dietary modifications should be made to lower them.
• Heat and cold treatments can provide relief from arthritis pain and inflammation.
• A diet rich in fresh fruits, vegetables, and whole foods can boost the immune system and promote overall health.
• Avoiding a diet high in red meat, processed foods, saturated fats, and added sugars and salts can help reduce inflammation, which is a characteristic of arthritis.
• Limiting alcohol and caffeine intake and quitting smoking are also beneficial.
• Synogen 40mg Capsule alleviates joint pain, discomfort, and stiffness, leading to a significant improvement in joint function and enhancement of daily activities.

Indication of Synogen 40mg Capsule

Synogen is a medication that contains Undenatured type II Collagen, also known as Chicken Collagen type II. It functions through a process called oral tolerization. Undenatured type II Collagen contains epitopes that interact with the peyer's patch in the intestine, which helps prevent the immune system from releasing collagen-specific T-cells that cause the degradation of collagen in the joints. By halting the erosion of joint cartilage, inflammation subsides, and the balance shifts toward rebuilding cartilage.

This medication is primarily indicated for the treatment of osteoarthritis, rheumatoid arthritis, as well as other joint pain and inflammation associated with injury and impaired joint function. By breaking the destructive cycle, Synogen allows for the repair of joint cartilage through normal collagen-building processes that are part of the cartilage remodeling process.

Pharmacology

Synogen 40mg Capsule contains undenatured collagen as its active ingredient. This component acts as a dietary mineral supplement and is effective in relieving joint pain and stiffness associated with osteoarthritis. Undenatured collagen plays a vital role in the formation and maintenance of joint cartilage. It provides strength and durability to the articular cartilage, supporting the bone joints. Additionally, it exhibits anti-inflammatory properties, effectively reducing joint inflammation. By addressing these aspects, Synogen 40mg Capsule improves joint flexibility and enhances physical performance.

Dosage & Administration of Synogen 40mg Capsule

Orally 1 capsule daily with water or as directed by the physician

Interaction

There is no known drug interaction.

Contraindications

Patients who are known to be allergic to chicken or eggs are contraindicated. 

Pregnancy & Lactation

There is not enough reliable information about the safety of taking Undenatured type II Collagen if you are pregnant or breastfeeding. So it is better to avoid the drug during pregnancy and lactation.

Precautions & Warnings

Avoid using Synogen 40mg Capsule if you have a known allergy to any of its ingredients. It is advised to use Synogen 40mg Capsule in children only under the recommendation of a doctor. If you are pregnant or breastfeeding, it is important to consult a doctor before using Synogen 40mg Capsule to ensure safety. Inform your doctor about any kidney problems or existing illnesses before taking Synogen 40mg Capsule. It is crucial to adhere to the recommended dosage and duration of use to avoid any potential adverse effects. Caution should be taken if the patient is allergic to chicken. The drug is not indicated to use in children and patients under 18 years of age

Storage Conditions

Keep away from direct sunlight and moisture, Store below 30° C temperature in a cool and dry place. Keep the medicine out of reach of children.