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Milk thistle, native to Europe and introduced to North America by early settlers, now thrives in various regions worldwide, including the eastern United States, California, South America, Africa, Australia, and Asia. Both the above-ground parts and seeds of the milk thistle plant are utilized for medicinal purposes.
Primarily taken orally, milk thistle is commonly used for liver disorders. It is employed to address liver damage stemming from various sources, such as exposure to chemicals, alcohol consumption, and chemotherapy. Additionally, it is used for liver damage caused by Amanita mushroom poisoning, nonalcoholic fatty liver disease, chronic inflammatory liver disease, cirrhosis of the liver, and chronic hepatitis.
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✅ Description:
Hepanor 70 (Milk thistle) is indicated for the treatment and prevention of:
- Liver disease (non-alcoholic & alcoholic)
- Liver cirrhosis (non-alcoholic & alcoholic)
- Infectious hepatitis
- Drug-induced hepatitis
- Liver disease secondary to diabetes mellitus
- Toxicity of narcotics
- Fatty liver
- Jaundice
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✔️ Composition:
Each capsule contains a standardized extract of Milk thistle 175 mg equivalent to Silymarin 140 mg and Milk thistle 87.50 mg equivalent to Silymarin 70 mg.
✔️ Pharmacology:
Silymarin is a well-known hepatoprotective agent. It stimulates RNA polymerase-A, enhances protein synthesis, and aids in the regeneration and repair of liver cells. Silymarin has antioxidant properties, preventing toxic substances from penetrating liver cells and protecting hepatocytes from various forms of damage. It also exhibits anti-lipid peroxidative, antifibrotic, anti-inflammatory, membrane stabilizing, immunomodulatory, and liver-regenerating effects.
✔️ Dosage & Administration:
For adults, take 1 to 3 capsules 2 to 3 times daily, or continue medication until symptom relief under the guidance of a physician. Not recommended for children without a physician's advice.
✔️ Interaction:
Concomitant use of Hepanor 70 and butyrophenones or phenothiazines has resulted in the reduction of lipid peroxidation.
✔️ Contraindications:
Hepanor 70 is contraindicated in patients with a known hypersensitivity to silymarin.
✔️ Side Effects:
Well tolerated in the recommended dose. Occasionally, a mild laxative effect may be observed.
✔️ Pregnancy & Lactation:
No experience is available regarding the use of Silymarin 70 mg or 140 mg during pregnancy and lactation. Use caution and follow the physician's advice if needed.
✔️ Storage Conditions:
Store in a cool & dry place, away from light & moisture. Keep out of reach of children.
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