Varizil IV 500mg/100ml Infusion

Overdose Effects:

Overdose of Varizil 500 mg/100 ml may result in symptoms such as vomiting, ataxia, and disorientation. Symptomatic and supportive treatment should be instituted in case of suspected overdose.

Missed Dose:

If a dose of Varizil IV is missed, it should be taken as soon as possible. However, if it's almost time for the next dose, the missed dose should be skipped, and the regular dosing schedule should be followed.

Pharmacology:

Varizil 500 mg/100 ml belongs to the imidazole class of antibacterial drugs and is classified therapeutically as an antiprotozoal agent. The 5-nitro group of Varizil 500 mg/100 ml is metabolically reduced by anaerobes. The reduced form of the drug interacts with DNA, exerting a bactericidal action.

Dosage & Administration of Varizil IV 500mg/100ml Infusion

The dosage and administration of Varizil 500 mg/100 ml vary depending on the condition being treated, age, and weight of the patient. It is available in tablet, suspension, vaginal gel, suppository, and IV infusion forms. Dosage recommendations for various conditions and patient populations are provided in detail in the prescribing information.

Pediatric Uses: Varizil 500 mg/100 ml should be administered with caution in pediatric patients with hepatic or renal impairment. Dosage adjustments may be necessary based on the patient's condition.

Interaction:

Varizil 500 mg/100 ml may interact with drugs such as disulfiram, alcohol, oral anticoagulants, lithium, cyclosporin, phenytoin or phenobarbital, 5-fluorouracil, and busulfan, leading to potentiation or reduction of their effects. Close monitoring and dose adjustments may be necessary when co-administering Varizil 500 mg/100 ml with these drugs.

Contraindications:

Varizil 500 mg/100 ml is contraindicated in patients with a history of hypersensitivity to Varizil 500 mg/100 ml or other Nitroimidazole derivatives.

Side Effects of Varizil IV 500mg/100ml Infusion

Common side effects of Varizil 500 mg/100 ml may include metallic taste, nausea, vomiting, diarrhea, drowsiness, and rashes.

Pregnancy & Lactation:

Varizil 500 mg/100 ml falls under US FDA Pregnancy Category B. It should be used during pregnancy only if needed. Caution is advised when administering Varizil 500 mg/100 ml to nursing women due to excretion in human milk.

Precautions & Warnings:

Patients receiving Varizil 500 mg/100 ml for extended periods should undergo regular hematological tests, especially leucocyte count, and be monitored for adverse reactions such as neuropathy. Caution is advised in patients with hepatic encephalopathy. Patients should be warned about urine discoloration.

Storage Conditions:

Varizil 500 mg/100 ml should be stored below 30°C, protected from light, and kept out of reach of children. It should not be used after the expiration date.