Tranexamic Acid (trans-4 aminomethyl-cyclohexanecarboxylic acid) is a potent antifibrinolytic agent, approximately ten times more effective than traditional hemostatic agents. It works by inhibiting the activation of plasminogen by both endogenous (e.g., urokinase) and exogenous (e.g., streptokinase) activators. This mechanism ensures effective bleeding control across various conditions.
Tranexamic Acid has a low acute toxicity profile and minimal chronic toxicity. It is well-absorbed orally, with effects seen within 15-30 minutes, and is primarily excreted through the kidneys at a slower rate than conventional hemostatics, providing a longer-lasting effect. Therapeutic doses do not interfere with normal clotting processes or promote thrombophilia, even with prolonged use.
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