Rolac 10mg Tablet

Uses of Rolac 10mg Tablet

• Postoperative Pain Relief

How does Rolac 10mg Tablet work?

Rolac 10mg Tablet works by stopping the production of a chemical substance that causes pain and swelling.

Side Effects of Rolac 10mg Tablet

• Nausea
• Vomiting
• Diarrhea
• Constipation
• Gas
• Stomach upset
• Dizziness

Quick Suggestions:

• Rolac 10mg Tablets a pain-relieving medicine. It is used to relieve moderate to severe pain, such as post-operative pain, tooth pain, joint pain, and muscle aches.
• Take it exactly as prescribed by your doctor. Do not take more or less than directed.
• Avoid taking Rolac 10mg Tablet with alcohol, as it may increase the risk of stomach bleeding.
• Do not take this medicine if you have had a stomach ulcer or bleeding in the past or if you have a bleeding disorder.
• If you have asthma, kidney or liver disease, or a history of allergic reactions to aspirin or other nonsteroidal anti-inflammatory drugs (NSAIDs), let your doctor know before taking Rolac 10mg Tablet.
• Tell your doctor if you are pregnant or planning to become pregnant, breastfeeding, or have any other medical conditions.
• Rolac 10mg Tablet should not be used in patients below 18 years of age.

Indication of Rolac 10mg Tablet

Rolac 10mg Tablet is a pain-relieving medicine. It is used for the short-term management of severe or intense pain, such as post-operative pain, tooth pain, joint pain, and muscle ache.

Pharmacology

Ketorolac is a nonsteroidal anti-inflammatory drug (NSAID) that works by inhibiting the activity of the cyclooxygenase enzyme (COX). COX is responsible for the production of prostaglandins, which are hormone-like substances involved in the inflammatory response and pain signaling. By inhibiting COX, ketorolac reduces the production of prostaglandins, leading to decreased inflammation and pain relief. This mechanism of action makes ketorolac an effective analgesic and anti-inflammatory medication.

Dosage & Administration of Rolac 10mg Tablet

Adult Dose:

For Moderately Severe Acute Pain:

• Oral: The short-term management of moderately severe acute pain that requires analgesia at the opioid level.
• IV: 30 mg as a single dose or 30 mg every 6 hours, not to exceed 120 mg per day.
• IM: 60 mg as a single dose or 30 mg every 6 hours, not to exceed 120 mg per day.
• PO (Oral): 20 mg once after IV or IM therapy, then 10 mg every 4-6 hours, not to exceed 40 mg per day.

Elderly (65 years and above):

• IV: 15 mg as a single dose or 15 mg every 6 hours, not to exceed 60 mg per day.
• IM: 30 mg as a single dose or 15 mg every 6 hours, not to exceed 60 mg per day.
• PO (Oral): 10 mg once after IV or IM therapy, then 10 mg every 4-6 hours, not to exceed 40 mg per day.

Dosing Considerations:

• Always begin with parenteral therapy (IV/IM); oral administration is indicated only as a continuation if necessary.
• The duration of therapy should not exceed 5 days.

Child Dose:

Children between 2-16 years:

• Single dose: 0.5 mg/kg IV/IM once, not to exceed 15 mg.
• Multiple doses: 0.5 mg/kg IV/IM every 6 hours, not to exceed 5 days.

Renal Dose:

For patients with severe renal impairment, the use of this medication is contraindicated. For patients with moderate renal impairment (moderately elevated serum creatinine):

• Use 50% of the recommended dosage, not to exceed 60 mg per day IV/IM.

Take Rolac 10mg Tablet as advised by your physician. It can be taken with or without food.

Swallow Rolac 10mg Tablet with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of Rolac 10mg Tablet therapy for you depending on your age, body weight, and disease condition. Continue to take Rolac 10mg Tablet for the stipulated duration prescribed by your doctor to achieve better results.

Interaction

Individuals may experience different drug interactions based on their unique medical history and the specific medications they are taking. Therefore, it is essential to consult with your doctor before starting any new medicine to identify potential interactions.

Rolac 10mg Tablet may interact with various drugs, such as Duloxetine, Atenolol, and Sertraline. It is also important to be cautious if you have liver disease, impaired kidney function, or heart disease, as Ketorol may pose risks for these conditions.

Consuming alcohol during treatment with Rolac 10mg Tablet is not recommended, as it may increase the risk of stomach bleeding.

Additionally, Rolac 10mg Tablet may cause fluid retention and edema, especially in individuals with pre-existing fluid retention. Close monitoring of blood pressure and heart function may be necessary in such cases.

This list is not exhaustive, and your doctor can provide further guidance on potential interactions specific to your situation. It is crucial to inform your healthcare provider about all the medications you are taking to ensure your safety and well-being.

Contraindications

• If you are allergic to Ketorolac or any other ingredient of Rolac 10mg Tablet.
• If you are allergic to other painkillers like aspirin or ibuprofen.
• If you have stomach or intestinal ulcers, bleeding, or perforation in the digestive tract.
• If you have kidney disease or liver disease and a history of bleeding in your brain.
• If you have experienced asthma, urticaria, or allergic-type reactions after painkiller use.
• Rolac 10mg tablets should not be used for managing pain before, during, and after coronary bypass surgery and for any major surgery.
• This medicine should not be used during labor as it may inhibit uterine contractions and can increase the risk of bleeding.
• You should not take this medicine if you are taking other painkillers.
• Rolac 10mg Tablets should not be used in patients below 18 years of age.

Pregnancy & Lactation

Ketorolac is classified as Pregnancy Category C in the first and second trimesters, meaning that animal studies have shown adverse effects on the fetus, but there are no well-controlled studies in pregnant women. In the third trimester, ketorolac is classified as Pregnancy Category D, indicating that there is positive evidence of human fetal risk based on human data, and the potential benefits from the use of the drug in pregnant women may outweigh the risks. In the third trimester, ketorolac may cause premature closure of the ductus arteriosus in the fetal heart, which can lead to serious complications in the newborn. Therefore, ketorolac should be used with caution during pregnancy, especially in the third trimester, and only if the potential benefits are deemed to outweigh the potential risks. It is essential to consult with a healthcare provider before taking any medication during pregnancy.

Precaution & Warnings:

• Avoid using Rolac 10mg Tablet if you are allergic to any of its components or if you have a history of asthma, severe heart problems, stomach ulcer or perforation, bleeding disorders (e.g., bleeding from the stomach, intestine, or brain), recent heart surgery, or blood circulation issues. Rolac 10mg Tablet can increase the risk of a fatal heart attack or stroke.
• Inform your doctor if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, liver or kidney problems before taking Rolac 10mg Tablet.
• Pregnant or breastfeeding individuals should avoid using Rolac 10mg Tablet.
• The medication may cause dizziness, so avoid driving or operating machinery if you feel lightheaded.
• Rolac 10mg Tablet is not recommended for children under 16 years of age due to the lack of safety and effectiveness data in this age group.
• If you experience stomach pain or notice any signs of bleeding in the intestine or stomach, such as blood in stools, stop taking Rolac 10mg Tablet immediately and consult your doctor.
• Do not take any other NSAIDs for pain relief along with Rolac 10mg Tablet unless specifically prescribed by your doctor.

Storage Conditions

• Store Rolac 10mg Tablets at room temperature away from direct sunlight, heat, and moisture.
• Keep out of the reach of children and pets.
• Discard any unused medicine properly. Do not flush it in the toilet or throw it into the drain.