Ketosteril Tablet (100pcs Box) | ePharma
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Ketosteril Tablet

Generic: Amino acid

Type: Tablet

Pack Size: 100 Pcs

  • Ketosteril Tablet is a nutritional supplement used to treat chronic kidney disease.
  • Enriched with essential amino acids and keto analogs.
  • It is a supportive therapy for patients suffering from kidney disease.

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Description:

Ketosteril Tablet is a medication that contains a combination of amino acids, including L-Histidine, L-Lysine, L-Threonine, L-Tryptophan, and L-Tyrosine. It is primarily used to prevent and treat the damages caused by faulty or deficient protein metabolism in chronic kidney diseases, especially in cases where dietary protein intake is limited.

Chronic kidney disease is a long-term condition that impairs the normal functioning of the kidneys, leading to difficulties in excreting toxins from the body. This condition often presents with symptoms such as nausea, vomiting, loss of appetite, fatigue, weakness, and sleep problems.

However, it's important to note that Ketosteril Tablet is not recommended for use if you have an allergy to any of the amino acids mentioned above (L-Histidine, L-Lysine, L-Threonine, L-Tryptophan, and L-Tyrosine). It should also be avoided in patients with hypercalcemia (high blood calcium levels) or disturbed amino acid metabolism.

If you have liver diseases, especially liver cirrhosis, chronic kidney diseases, renal hyperphosphatemia (excess blood phosphate levels), renal osteodystrophy (a metabolic renal disease), or renal insufficiency, you should exercise caution when using Ketosteril Tablet.

Pregnant and breastfeeding women should also use this medication with caution, and it's advisable to consult a doctor before taking it. Similarly, caution should be exercised when administering KETOSTERIL TABLET to children aged 13 years or older and elderly patients above 60 years of age.

Some common side effects associated with KETOSTERIL TABLET include signs of increased levels of alanine, glutamine, and glutamate, which can manifest as anxiety and restlessness. On the other hand, signs of decreased levels of glycine and BCAA (branched-chain amino acids) may result in impaired growth and protein wasting. If you experience any worsening of these conditions, it is recommended to contact your doctor or visit a nearby hospital for further evaluation.

Please note that this information is not exhaustive, and it's always best to consult a healthcare professional or your doctor for specific advice regarding your condition and the appropriate use of Ketosteril Tablet 

Safety Advices


Alcohol
UNSAFE

There is limited information on the interaction of Ketosteril tablets with alcohol. Ask your doctor for advice on the use of alcohol with this medicine.


Pregnancy
CONSULT YOUR DOCTOR

There is limited information on the effect of Ketosteril tablets on pregnancy. This medicine should only be used in pregnant women if recommended by the doctor.


Breastfeeding
CAUTION

Ketosteril Tablets should be used with caution in breastfeeding women. Consult your doctor before taking it.


Driving
CAUTION

Ketosteril tablet has no effect on driving ability. However, if you experience any effects after taking this medicine that may affect your ability to drive safely, it is advised to avoid driving.


Kidney
CAUTION

Ketosteril Tablet should be used with caution in patients with chronic kidney diseases, renal hyperphosphatemia (excess blood phosphate levels), renal osteodystrophy (metabolic renal disease), and renal insufficiency. Consult your doctor for advice before taking it.


Liver
CAUTION

Ketosteril Tablets should be used with caution in patients with liver diseases, particularly liver cirrhosis. Consult your doctor before taking it.

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Uses of Ketosteril Tablet

Prevent and treat the damages caused by faulty or deficient protein metabolism in chronic kidney diseases in association with limited dietary protein intake

How does Ketosteril Tablet work?

Ketosteril Tablet  helps in managing chronic kidney diseases where L Histidine, L Lysine, L Threonine, L Tryptophan, and L Tyrosine after getting absorbed get converted into corresponding essential amino acids by taking nitrogen from non-essential amino acids, thereby decreasing the formation of excessive urea and toxins in the body. These amino acids also put a positive effect on bone health by optimizing the phosphate and parathyroid hormone levels in the body.

Side Effects of Ketosteril Tablet
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal pain
Quick Suggestions:
  • The Ketosteril tablet comprises the necessary amino acids for uremic patients.
  • You have been prescribed Ketosteril Tablet for the treatment of chronic kidney disease.
  • Taking it along with a low-protein diet helps in delaying the progression of kidney diseases and dialysis initiation.
  • Ensure that you maintain adequate calorie intake during therapy.
  • Regularly monitor serum calcium levels as instructed by your doctor. Reduce your intake of vitamin D and other calcium sources if the levels are high.
  • It decreases nitrogen supply and provides calcium.
  • It aids in the treatment of chronic kidney disease patients on conservative management therapy (CKD stage I, II, III).
  • It slows the progression of renal disease during the pre-dialysis period.
  • It also promotes the production of muscle protein.
Indication of Ketosteril Tablet
  • Ketosteril, also known as a compound-ketoacid tablet, is used to treat chronic kidney disease (CKD) patients who have renal impairment caused by a problem with protein metabolism. The effects are improved by low-protein diets.
  • ​Ketosteril is part of the conservative treatment of patients with Chronic Kidney Disease.
  • Ketosteril contains amino acids, partly in the form of their corresponding keto analogs, essential for patients with Chronic Kidney Disease.
  • In combination with a protein-restricted diet, Ketosteril is an excellent tool to treat Chronic Kidney Disease in the predialysis period.
Pharmacology

Chronic kidney disease (CKD) is a condition characterized by the gradual loss of kidney function over an extended period of time. If left untreated or unmanaged, CKD can progress and potentially become permanent. Ketosteril Tablet is a medication that combines essential amino acids and is often prescribed in conjunction with a low or very low-protein diet to help slow down the progression of CKD and enhance the individual's quality of life.

Ketosteryl (INN - keto analogs of amino acids) promotes the restoration of metabolism, disrupted due to inadequate intake of essential amino acids in the body against a violation of the kidneys. Promotes the synthesis of protein in the body, reduces the degree of toxic effects of protein metabolism products on the body, and improves the overall condition of patients with chronic renal dysfunction.

Managing CKD involves various aspects, including dietary modifications, lifestyle changes, and potentially medication, depending on the severity and specific needs of the individual. Therefore, it's essential to work closely with your healthcare provider to develop a comprehensive treatment plan that suits your condition and requirements.

Dosage & Administration of Ketosteril Tablet
  • The medicine is taken orally during meals. Tablets must be swallowed whole while drinking with a sufficient amount of liquid - this is how they are best absorbed and included in the metabolic processes.
  • The dosage of the drug is prescribed in accordance with the weight of the patient at the rate of 1 tablet per 5 kg per day. The daily dose is divided into 3-4 doses. The average daily dose for an adult is 12 to 24 tablets.
    Instruction on Ketosteril suggests that the treatment course be carried out throughout the period of the decrease in glomerular filtration below 25 ml/min. Simultaneously, a diet with a reduced amount of protein is prescribed. With the prolonged intake of Ketosteril, the content of calcium in the blood should be checked periodically.
  • If not otherwise prescribed, take 4-8 tablets three times a day during meals. Swallow whole. This dosage applies to adults (70kg/BW)
  • Should be taken with food: Swallow whole, do not chew/crush.
Interaction

Interaction of Ketosteril with other medications

  • Medicines used to treat bacterial infection such as tetracyclines (Ex. doxycycline), quinolines (Ex. ciprofloxacin, norfloxacin)
  • Medicines containing iron, fluoride, estramustine
  • Medicines used to treat arrhythmias such as cardioactive glycosides Ex. digoxin
  • Aluminum hydroxide (a medicine used to treat acidity)

Ketosteril should not be used at the same time:

  • With calcium preparations - this can lead to hypercalcemia;
  • With preparations that form hardly soluble compounds with calcium - antibiotics of the tetracycline group, antibiotics of the quinolone group, and drugs containing iron, estramustine, and fluorine; between taking these drugs and Ketosteril should be a minimum of two hours.

When the condition improves against the background of Ketosteril administration, in order that the acid-base balance does not break, gradually reduce the dose of aluminum hydroxide, which was prescribed in acidosis (shifting the acid-base balance of the body towards increasing acidity).

Contraindications
  • If you are allergic to isoleucine, leucine, phenylalanine, valine, methionine, lysine, threonine, tryptophan, histidine, tyrosine, nitrogen, calcium, or any other ingredient of Ketosteril tablet.
  • If you have high calcium levels.
  • If you have a disturbed amino acid metabolism.
Pregnancy & Lactation

There is limited information on the effect of Ketosteril tablets on pregnancy & Breastfeeding

Precautions & Warnings
  • Keep your physician informed about your medical condition and medicines before taking the Ketosteril tablet.
  • Consult your doctor if you are pregnant, planning to become pregnant, or are breastfeeding.
  • Limit or avoid alcohol consumption.
  • Quit smoking & intake fo alcohol
  • Ketosteril Tablet is not recommended for use if you have hypercalcemia (high blood calcium levels) or disturbed amino acid metabolism.
  • Additionally, if you have hereditary phenylketonuria, a condition that causes an accumulation of phenylalanine in the body due to inherent disorders, it is important to inform your doctor before taking Ketosteril Tablet.
  • Ketosteril should not be administered with individual intolerance to its components, elevated calcium levels in the blood, impaired amino acid metabolism (for example, phenylketonuria, in which amino acid phenylalanine is disrupted), and children under 3 years of age.
Storage Conditions
  • Store Ketosteril tablets in a cool and dry place below 25°C protected from direct sunlight and moisture.
  • Keep away from children and pets.
Frequently Asked Questions (FAQ)

Adults are usually advised to take the pills with meals since it aids in the appropriate absorption or use of the amino acids. Chewing the pills is not permitted. In situations of renal failure, Ketosteril Tablet should be used in conjunction with a protein-restricted diet. The length of therapy is determined on the severity of the renal disease. Follow your doctor's instructions, and if you experience any uneasiness/discomfort or response, call your doctor right away.

Ketosteril tablet should be taken as directed by your doctor. Preferably take it during meals. Swallow it whole with a glass of water. Do not cut, break or chew the medicine. It would be best if you took it at a fixed time for optimal results. Do not consume more than the dose prescribed by your doctor.

Ketosteril Tablet contains an important amino acid. It has a metabolic advantage on the body when used as a therapeutic. Ketosteril Tablet is most typically used in individuals with chronic renal failure as nutrition treatment or dietary supplements. In patients with renal failure, this medication reduces an unnecessary rise in urea levels in the blood caused by the use of non-essential amino acids.

Ketosteril Tablet should be used with caution with children (aged 13 years or above) and elderly patients (above 60 years). Consult your doctor before taking it to avoid any harm.

It is a nutritional supplement. It works by enhancing protein metabolism in the body and thereby improving kidney function.

High blood pressure, diabetes, high cholesterol, kidney infections, kidney inflammation, recurring kidney stones, an enlarged prostate, and long-term, frequent use of certain medicines such as lithium and nonsteroidal anti-inflammatory drugs (NSAIDs) are common causes of CKD.

There are usually no symptoms of kidney disease in the early stages. However, in the advanced stage, symptoms may include tiredness, swollen ankles, feet or hands, shortness of breath, feeling sick, and blood in the urine.

To treat your condition effectually, continue taking the Ketosteril tablet for as long as your doctor has prescribed. Please do not stop taking Ketosteril tablets without consulting your doctor.

Ketosteril tablet is usually administered to patients with a glomerular filtration rate (GFR) of less than 25ml/min.
Ratings & Reviews

1
Verified Buyer
19 Dec, 2023
I am having a terrible time with this domain. Cannot download the app as my phone says new android version doesn't support the app. Then when I try to log in online, the OTP doesn't come. I can just click verify without an OTP and it takes me into my account. I placed one order which after delivery shows order confirmed but not delivered ( this means that my account won't reflect any Cashback coupons for the next order). Delivery was good, helpful courier. Unfortunately the other apps like Arogga or Oshudpatro are much better to order.

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