Galvus Met 50/850mg 10pcs

Galvus Met 50mg/850mg Tablet is a combination of two antidiabetic medicines: Metformin and vildagliptin. Metformin is a biguanide which decreases the production and absorption of sugar in your body and allows better use of existing insulin. Vildagliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar.

Administration & Dosage of Galvus Met 50mg/850mg

This combination may be started twice daily, with one tablet in the morning and the other in the evening, depending on the patient's current Metformin dose. Patients who are currently taking Vildagliptin and Metformin as separate tablets may be switched to this combination, which contains the same doses of both drugs. Vildagliptin doses greater than 100 mg are not recommended.

Interaction of Galvus Met 50mg/850mg

When Vildagliptin (100 mg once daily) was combined with Metformin Hydrochloride, no clinically significant pharmacokinetic interaction was observed (1,000 mg once daily). Drug interactions are unlikely with Vildagliptin. Vildagliptin is unlikely to interact with co-medications because it is not a cytochrome P (CYP) 450 enzyme substrate, nor does it inhibit or induce CYP 450 enzymes.

Contraindications of Galvus Met 50mg/850mg

Patients who have a known hypersensitivity to Vildagliptin, Metformin Hydrochloride, or any of the excipients should avoid this combination. It's not recommended for people who have kidney disease or dysfunction, a heart attack, or septicaemia.

Side Effect of Galvus Met 50mg/850mg

Headache, tremor, dizziness, nausea, hypoglycemia, and other side effects are the most common.

Pregnancy & Lactation concern while using Galvus Met 50mg/850mg

Because there are no adequate and well-controlled studies in pregnant women, this combination should not be used during pregnancy unless the potential benefit outweighs the risk to the fetus. There have been no studies done on the components of this combination. Because Vildagliptin and/or Metformin Hydrochloride are unknown.

Precautions & Warnings for Galvus Met 50mg/850mg

Metformin accumulation can cause lactic acidosis. If metabolic acidosis is suspected, treatment should be stopped immediately and the patient admitted to the hospital. Patients with normal renal function should have their serum creatinine levels checked at least once a year, and patients with serum creatinine levels above the upper limit of normal and elderly patients should have their serum creatinine levels checked 2–4 times a year.