Doxin 100mg Capsule

Uses of Doxin 100mg Capsule

Treatment of-

• Bacterial infections
• Acne

How does Doxin 100mg Capsule work?

• Doxycycline interferes with the formation of proteins, which are essential for the survival and growth of bacteria. This prevents bacterial replication and thus controls the infection.

Side Effects of Doxin 100mg Capsule

• Stomach pain
• Headache
• Joint pain
• Blurred vision
• Diarrhea
• Loss of appetite
• Dry mouth
• Nausea or Vomiting
• Upset stomach

Quick Suggestions:

• Your doctor has prescribed Doxin 100mg Capsule to cure your infection and improve symptoms.
• Take it with food and plenty of water to avoid stomach upset.
• Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection come back and harder to treat.
• Take it while you are sitting or standing, to prevent any throat irritation. Do not lie down for at least 30 minutes after taking Doxin 100mg Capsule.
• Avoid excessive sun exposure and use sunscreen and protective clothing when outdoors.

Indication of Doxin 100mg Capsule

 Doxin 100mg Capsule is used to-

• Treat various bacterial infections like that of the chest, lung or nose (Ex. bronchitis, pneumonia, sinusitis), urinary tract (Ex. cystitis, urethritis), skin (Ex. acne), eyes or sexually transmitted diseases (Ex. gonorrhoea, syphilis, chlamydia)
• Treat fevers associated with louse or tick bites and malaria (when chloroquine is ineffective)
• Prevent certain infections like scrub typhus, Rocky Mountain spotted fever, travellers’ diarrhoea, malaria and leptospirosis

Pharmacology

Doxycycline is a tetracycline antibiotic that exerts its antimicrobial effect by binding to the 30S ribosomal subunit of bacteria. By doing so, it interferes with the bacterial protein synthesis process, preventing the bacteria from producing essential proteins needed for their growth and replication.

Doxycycline exhibits bacteriostatic activity, which means it inhibits the growth and reproduction of bacteria rather than directly killing them. It is effective against a wide range of both gram-positive and gram-negative bacteria, making it useful in the treatment of various bacterial infections.

As with any antibiotic, it's essential to use doxycycline responsibly and as prescribed by a healthcare professional to avoid the development of antibiotic resistance and to ensure its effectiveness in treating bacterial infections.

Dosage & Administration of Doxin 100mg Capsule

Adult Dose:

• For susceptible infections: 200 mg on day 1 as a single or divided dose, followed by 100 mg once daily. For severe infections, maintain the initial dose throughout the treatment course.
• For sexually transmitted diseases: 100 mg orally every 12 hours for 7 days.
• For syphilis (early): 100 mg orally twice daily for 2 weeks.
• For syphilis (>1 year duration): 100 mg orally twice daily for 4 weeks.
• For acute epididymal-orchitis caused by N. gonorrhea or C. trachomatis: 100 mg orally twice daily for at least 10 days.
• For acne, rosacea: 50 mg daily for 6-12 weeks.
• For prophylaxis of malaria: 100 mg orally once a day; begin taking 1-2 days before travel and continue daily during travel and for 4 weeks after leaving the malaria-infested area.

Child Dose:

• For children >8 years and <45 kg: 2-4 mg/kg/day every 12 hours.

Always take Doxin 100mg Capsule as advised by your physician, without crushing or chewing it, and follow their recommended dose and duration of treatment. Do not discontinue the medication unless advised by your doctor. The specific dose and duration will depend on the individual's age, body weight, and medical condition.

Interaction

Interactions between medications can sometimes lead to unexpected side effects or reduce the effectiveness of the treatment. It's essential to inform your doctor about all the medicines you are taking, including prescribed medications, over-the-counter drugs, herbal supplements, and dietary supplements. This information will help the doctor to make appropriate treatment decisions and avoid any potential interactions.

Specifically, for Doxin 100mg Capsule, you should be cautious when using them with certain medications, such as:

1. Medicines are used to treat brain-related disorders (e.g., alprazolam) or anti-epileptic medicines (e.g., phenytoin).
2. Medicines are used to treat acne (e.g., isotretinoin), oral contraceptives, anticoagulants (e.g., warfarin and heparin), penicillin antibiotics, and immunosuppressants (e.g., cyclosporin).
3. Antacids and supplements containing iron, calcium, etc., should not be taken simultaneously with Doxin 100mg Capsule. There should be a gap of at least 2 hours between taking Doxin 100mg Capsule and these supplements.

Additionally, it's crucial to inform your doctor if you have a planned surgery or vaccination scheduled, as certain medical

Contraindications

• If you are allergic to Doxycycline or any other components of this medicine.
• If you are pregnant or trying to get pregnant or breastfeeding.

Pregnancy & Lactation

During pregnancy, the use of doxycycline is generally not recommended unless considered essential for the welfare of the patient. The majority of reported experience with doxycycline during human pregnancy is limited to short-term exposure in the first trimester. There are no human data available to assess the effects of long-term therapy with doxycycline in pregnant women, such as in the treatment of anthrax exposure. Animal studies have shown evidence of embryotoxicity when animals were treated with doxycycline early in pregnancy.

Doxycycline is excreted in human milk, but the extent of absorption by breastfed infants is not known. Short-term use of doxycycline by lactating women is not necessarily contraindicated. However, the effects of prolonged exposure to doxycycline in breast milk are unknown. Due to the potential for serious adverse reactions in nursing infants from doxycycline, a decision should be made by the mother, in consultation with her physician, to either discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother's health.

If you are pregnant or breastfeeding, it is essential to discuss the risks and benefits of using doxycycline with your healthcare provider before starting or continuing the medication. They can help you make an informed decision regarding the appropriate course of action for your specific situation.

Precautions & Warnings

The use of drugs from the tetracycline group, including doxycycline, during tooth development (which includes the last half of pregnancy, infancy, and childhood up to the age of 12 years) may lead to permanent discoloration of the teeth. Due to this risk, tetracyclines should generally not be used in this age group unless there are no other effective treatment options or if other drugs are contraindicated.

In the case of lactation, doxycycline enters breast milk, and its use is not recommended in breastfeeding women. The potential for adverse effects on nursing infants, such as tooth discoloration or other side effects, should be considered when making decisions about using doxycycline while breastfeeding.

If there is a need for treatment with doxycycline during pregnancy, infancy, childhood, or while breastfeeding, it is crucial to consult with a healthcare professional. They can evaluate the potential risks and benefits and help make an informed decision based on the specific circumstances of the patient. In some cases, alternative treatment options may be considered to minimize the risk of adverse effects on tooth development or breastfeeding infants.

Storage Conditions

Store the medicine below 25°C in a cool and dry place. Keep it away from children and pets.