Amaryl 4mg | Dosage | Interaction | Contridication | Price | ePharma
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Amaryl 4mg Tablet

Generic: Glimepiride

Type: Tablet

Pack Size: 15 Pcs

Glimepiride is employed to manage non-insulin-dependent diabetes mellitus (type 2) alongside diet and exercise to reduce blood glucose levels. It's also combined with insulin for patients with uncontrolled hyperglycemia, either due to diet and exercise or with an oral hypoglycemic agent.


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Discount Price: ৳ 300.11
MRP: ৳ 315.9 5% Off

⪼ Save  ৳: 15.8  in this Product


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Description:

Amaryl 4mg Tablet contains Glimepiride, an Anti-diabetic agent. It's used for Type II diabetes when diet and exercise aren't enough to control blood sugar. This chronic condition results in high blood glucose due to insufficient insulin production or reduced sensitivity of body cells to insulin's effects.

Your doctor may suggest lifestyle changes like a healthy diet, exercise, and quitting alcohol. Inform your doctor of liver/kidney issues, hormonal problems, or genetic disorders. Amaryl 4mg Tablet isn't for Type I diabetes. In pregnancy or breastfeeding, consult your doctor.

Hypoglycemia (low blood sugar) is a common side effect. Symptoms include hunger, sweating, shakiness, weakness, and irregular heartbeat. Regular blood sugar monitoring and dose adjustments by your doctor help prevent this. Carry a sugary snack in case of hypoglycemia symptoms. If no improvement, consult your doctor.

Safety Advices


Alcohol
UNSAFE

It is advised not to take Amaryl 4mg Tablet with alcohol, as alcohol intake can unpredictably affect the blood sugar-lowering action of the medication, potentially leading to harmful outcomes.


Pregnancy
CONSULT YOUR DOCTOR

Amaryl 4mg Tablet falls under pregnancy Category C, meaning there are no well-controlled studies conducted on pregnant women. If you're taking this medication during pregnancy, discontinue its use at least 2 weeks before your due date or as directed by your doctor.


Breastfeeding
CONSULT YOUR DOCTOR

It's not recommended for breastfeeding mothers, as Amaryl 4mg Tablet can pass into breast milk and pose a risk of low blood sugar in the infant. Consult your doctor for further


Driving
CAUTION

Caution is advised, particularly for patients with fluctuating glucose levels. Amaryl 4mg Tablet can impair concentration or reaction abilities, especially if blood sugar is too low (hypoglycemia) or too high (hyperglycemia), or if visual problems arise due to such conditions. Therefore, driving or using machinery is not recommended in such circumstances.


Kidney
CONSULT YOUR DOCTOR

Amaryl 4mg Tablet is not recommended for patients with liver dysfunction. Consult a doctor before taking this medication, as it may potentially cause liver damage.


Liver
CONSULT YOUR DOCTOR

Similarly, Amaryl 4mg Tablet is not recommended for patients with kidney dysfunction. Prior consultation with a doctor is advised, as it might lead to kidney damage.

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Uses of Amaryl 4mg Tablet
  • Type 2 Diabetes
How does Amaryl 4mg Tablet work?

Amaryl 4mg Tablet works by increasing the secretion of insulin from the pancreas and also regulates the release of glucose from the liver.

Side Effects of Amaryl 4mg Tablet
  • Headache
  • Dizziness
  • Nausea
  • Fever
  • Confusion
  • Edema (Swelling)
  • Urticaria
  • Rash
  • Anorexia
  • Heartburn
  • Bone Marrow Suppression
  • Thrombocytopenia
Quick Suggestions:
  • Incorporate regular exercise and a balanced diet into your routine, along with any other prescribed diabetes medications.
  • While using Glimepiride, be cautious when driving or operating machinery until you understand its effects on you.
  • Hypoglycemia can occur when combining Glimepiride with other antidiabetic medicines, alcohol, or skipping meals.
  • Carry sugary food or juice to manage hypoglycemic symptoms like cold sweats and tremors.
  • Liver function checks may be needed, and report symptoms like abdominal pain, appetite loss, or jaundice. Keep track of your blood sugar levels during Glimepiride usage.
Indication

Amaryl 4mg Tablet is prescribed for individuals with type 2 diabetes to lower high blood sugar levels when accompanied by a balanced diet and exercise. It can be used alongside insulin or other oral antidiabetic medications. By enhancing insulin production and secretion from the pancreas beta cells, Amaryl 4mg Tablet effectively reduces post-meal blood sugar levels.

Pharmacology

Glimepiride stimulates the insulin release from pancreatic β-cells and reduces glucose output from the liver. It also increases insulin sensitivity at peripheral target sites.

Dosage & Administration of

For adult Type 2 diabetes mellitus patients, the initial dose of Glimepiride is 1-2 mg daily, which can be increased by 1-2 mg at 1-2 week intervals. The maintenance dose is 4 mg daily, with a maximum of 6 mg daily. Elderly patients start with 1 mg once daily. In severe hepatic impairment, it's contraindicated.

In renal impairment, a dose of 1 mg PO qDay is recommended; adjust based on fasting blood glucose levels. Avoid severe cases. Take Amaryl 4mg Tablet after meals, swallowing with water, and don't crush or chew it. Follow your doctor's instructions on dose and duration, and avoid stopping without the doctor's advice.

Overdosage:

In case of accidental overdose, symptoms of hypoglycemia (increased hunger, sweating, shakiness, confusion) may occur. Consume sugary food immediately. If symptoms persist, seek medical help.

Missed Dose:

If you miss a dose of Amaryl 4mg Tablet, take it when remembered. If it's close to the next dose, skip the missed one. Avoid doubling doses.

Interaction

Drug Interactions:

Before taking Amaryl 4mg Tablet, inform your doctor about any ongoing medications, including:

  • Diabetes medications (e.g., insulin, metformin)
  • Pain and inflammation relievers (e.g., aspirin, ibuprofen)
  • Urinary infection treatments (e.g., amikacin, nitrofurantoin)
  • Antibiotics (e.g., tetracyclines, clarithromycin)
  • Antifungal medications (e.g., fluconazole, miconazole)
  • Blood clot prevention drugs (e.g., warfarin)
  • Muscle-building agents (e.g., nandrolone, oxymetholone)
  • Hormone replacement therapies (e.g., testosterone)
  • Anti-depressants (e.g., fluoxetine)
  • Cholesterol-lowering drugs (e.g., fenofibrate)
  • Blood pressure medications (e.g., lisinopril, atenolol)
  • Medications for heart rhythm abnormalities (e.g., disopyramide)
  • Gout treatments (e.g., allopurinol)
  • Cancer treatments (e.g., cyclophosphamide)
  • Asthma medications (e.g., salbutamol)
  • Emergency medications (e.g., adrenaline)
  • Medications for constipation (e.g., lactulose)
  • Epilepsy treatments (e.g., phenytoin)
  • Medications for mental illness (e.g., chlorpromazine)
  • Corticosteroids (e.g., prednisolone)
  • Thyroid medications (e.g., levothyroxine)
  • Asthma medications (e.g., salbutamol)
  • Adrenaline (used in emergencies)
  • Medications for constipation (e.g., lactulose)
  • Medications for epilepsy (e.g., phenytoin)
  • Barbiturates (used for sleep)
  • Medications to reduce eye pressure (e.g., acetazolamide)
  • Glucagon and diazoxide (for low blood sugar)
  • Cimetidine (used for stomach ulcers)
Contraindications

Avoid taking Amaryl 4mg Tablets if:

  • You are allergic to Glimepiride, Sulfonylureas, Sulfonamides, or any other ingredient in the tablets.
  • You have type 1 diabetes.
  • You are experiencing symptoms like fatigue, nausea, frequent urination, and muscle stiffness (indicative of diabetic ketoacidosis).
  • You have severe kidney or liver disease.
Pregnancy & Lactation

Avoid taking Glimepiride during pregnancy. If you are pregnant or planning to become pregnant, consult your doctor and consider shifting to Insulin therapy. For breastfeeding mothers, Glimepiride should not be taken, as it could harm the child. If using this medication, consider switching to alternative feeding methods.

Precautions & Warnings
  • There's an increased risk of cardiovascular (CV) mortality associated with Amaryl 4mg Tablets. Caution is advised for elderly patients and those with hepatic or renal impairment. In cases of congestive heart failure (CHF) or hepatic cirrhosis, there's a potential for the syndrome of inappropriate secretion of antidiuretic hormone (SIADH).
  • Regular monitoring of blood glucose concentration is important. Use during pregnancy and lactation requires careful consideration. The excretion of Amaryl 4mg tablets in breast milk is unknown, so it's recommended to avoid its use during lactation.
  • It's important to follow these precautions and consult your doctor if you have any concerns about using Amaryl 4mg Tablet, especially if you fall into any of the mentioned risk categories.
Storage Conditions

Do not store at temperatures above 30°C. Keep out of the reach of youngsters and away from light.

Frequently Asked Questions (FAQ)

Amaryl 4mg Tablet typically starts to show its effects within about an hour after being taken orally. The peak effect of the medication is usually reached within 2 to 3 hours.

The effects of Amaryl 4mg Tablet typically last for an average duration of around 48 hours.

Absolutely, taking Amaryl 4mg Tablet as prescribed by your doctor is crucial for effective management of your diabetes. It's recommended to take Amaryl with your first meal of the day, preferably in the morning. Maintaining a consistent schedule by taking it at the same time every day helps ensure consistent blood sugar control and optimal results. If you have any doubts or concerns about how to take the medication, it's always best to consult your doctor for guidance.

It's crucial for individuals who are already taking Amaryl 4mg Tablet to consult their doctor before considering the use of contraceptive pills. Oral contraceptive pills can influence how the body responds to sugar and may potentially affect blood sugar levels. In some cases, the doctor might need to adjust the dose of Amaryl 4mg Tablet to ensure optimal diabetes management while using contraceptive pills. Open communication with your healthcare provider is essential to ensure your overall health and well-being.

The primary side effect of Amaryl 4mg Tablet is hypoglycemia. Regular blood sugar monitoring by your doctor is essential to adjust the dose appropriately. For added caution, keep sugary snacks handy, like biscuits or glucose drinks, to counteract hypoglycemic symptoms. If your condition doesn't improve, consult your doctor.
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Check our pricing section for Amaryl 4mg Tablet price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
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