Ace XR | Paracetamol | 665mg | View Uses, Dosage & Price | ePharma
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Ace XR Tablet

Generic: Paracetamol

Type: Tablet

Pack Size: 10 Pcs

Paracetamol Tablet is the most widely used over-the-counter (OTC) medication. It is used for the treatment of fever. It also provides relief from headaches, toothache, backaches, nerve pain, musculoskeletal pain, etc. associated with/without fever.


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Discount Price: ৳ 18.6
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Description:

  • Ace XR Tablet is an analgesic medication primarily used to relieve pain associated with various conditions such as backache, headache, arthritis, menstrual pain, common cold, and toothache. It belongs to the class of non-steroidal anti-inflammatory drugs (NSAIDs) and also helps reduce fever.
  • It is important not to take this medicine if you are allergic to it, have a serious liver disorder, or consume excessive alcohol regularly or have a history of alcoholism. The recommended dosage should not be exceeded, and the tablet should be swallowed whole without crushing or mixing it in water.
  • For adults, the usual dose is 1-2 tablets (500mg or 650mg) with a minimum interval of 4 hours between doses. The total daily dose should not exceed 4g. It is advised to take the medicine with food or milk. If a dose is missed, it should not be doubled up.
  • It is important to follow the prescribed instructions and not increase the dose or frequency. Avoid consuming alcohol and other medications containing acetaminophen while using this medication. It is also recommended to maintain adequate hydration unless instructed otherwise.
  • If any unusual bleeding (stool, mouth, urine) or bruising, unusual fatigue and weakness, changes in elimination patterns, or changes in the color of urine or stool occur, it should be reported. In case of overdose or toxicity, appropriate measures such as acetylcysteine and activated charcoal should be taken as prescribed.

Safety Advices


Alcohol
UNSAFE

Consumption of alcohol is not recommended during treatment with Ace XR Tablet as it may cause liver damage. Consult your doctor immediately if you experience any signs and symptoms of liver injury like fever, rash, nausea, vomiting, fatigue, dark urine, jaundice, etc. 


Pregnancy
CONSULT YOUR DOCTOR

Ace XR Tablet may be used during pregnancy for the shortest time possible and the lowest effective dose. However, it is recommended to use this medicine after consultation with your doctor.


Breastfeeding
CONSULT YOUR DOCTOR

Ace XR Tablet is considered safe during breastfeeding. It passes into the breastmilk in very small amounts which are not known to harm your baby. However, it is recommended to use this medicine after consultation with your doctor.


Driving
CAUTION

Ace XR Tablet is not likely to affect your ability to drive or use machines.


Kidney
CONSULT YOUR DOCTOR

The use of Ace XR tablets affects the kidney mildly. If the patient is suffering from kidney disease it can cause major effects.


Liver
CONSULT YOUR DOCTOR

The use of Ace XR Tablet affects the liver mildly. If the patient is suffering from liver impairment, it can cause major effects.

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Uses of Ace XR Tablet
  • Relieves mild to moderate pain (such as headache, toothache, and joint pain)
  • Lowers fever and relieves the symptoms of cold or flu
  • Post Vaccination Fever
How does Ace XR Tablet work?

Ace XR works by decreasing the intensity of pain signals in the brain. It also prevents the release of prostaglandins, the chemical that causes pain and an increase in body temperature. 

Side Effects of Ace XR Tablet
  • Nausea Or Vomiting
  • Fatigue
  • Allergic Skin Reaction
  • Gastric / Mouth Ulcer
  • Anemia
  • Stevens-Johnson Syndrome
Quick Suggestions:
  • Paracetamol should be taken with food or milk to prevent an upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long-term use may lead to serious complications such as stomach bleeding and kidney problems.
  • Do not take indigestion remedies (antacids) within 2 hours of taking Paracetamol.
  • Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
  • Inform your doctor if you have liver disease as your dose may need to be adjusted.
  • Your doctor may regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Indication

Paracetamol is suitable for fever, common cold and flu, headache, toothache, earache, body pain, myalgia, neuralgia, dysmenorrhea, sprain, colic, back pain, postoperative pain, postpartum pain, inflammatory pain and pain in children after vaccination. It is also suitable for rheumatic pain and osteoarthritis and joint stiffness.

Pharmacology

Paracetamol has analgesic and antipyretic properties, and its anti-inflammatory activity is weak. Paracetamol (acetaminophen) is believed to act mainly on the central nervous system, increasing the pain threshold by inhibiting two isoforms of cyclooxygenase COX1, COX2, and COX3, which are involved in the synthesis of prostaglandin (PG). Paracetamol is a derivative of p-aminophenol, has analgesic and antipyretic effects, and has weak anti-inflammatory activity. Paracetamol is one of the most widely used, safest, and quick-acting analgesics. It is well tolerated and does not have various aspirin side effects.

Dosage & Administration of Ace XR Tablet

The recommended dosage and administration instructions for Ace XR Tablet are as follows:

  • Adult: The recommended dose for adults is 50-150 mg taken three times daily, depending on the individual requirement and tolerance of the patient.
  • Children (from 3 months to 6 years): The recommended dose for children in this age group is 5 mg/kg/day divided into three doses.
  • Children (from 6 to 14 years): The recommended dose for children in this age group is 2-4 mg/kg/day divided into three doses.

It is important to follow the directions provided by the registered physician. Take Ace XR Tablet as advised, either with or without food. When taking the tablet or capsule form, swallow it whole with a glass of water. Do not crush or chew the medicine. Please consult your physician or refer to the specific instructions provided with the medication for accurate dosing and administration information.

Interaction

When taking Ace XR Tablet, it is important to be aware of potential interactions with other substances. Here are some interactions to consider:

  • Interaction with Alcohol: Consuming alcohol while taking Ace XR Tablet can be dangerous as it may increase the risk of side effects such as dizziness, fatigue, fever, and joint pain. It can also have a severe effect on the liver.
  • Interaction with Other Medications: Ace XR Tablet may interact with other medications such as Ketoconazole, Metformin, and Anti-hypertensives if taken together. It is important to exercise caution and follow the advice of your healthcare provider. Additionally, Barbiturates, carbamazepine, hydantoins, and sulfinpyrazone can increase the risk of liver damage when combined with acetaminophen. Chronic ethanol abuse can also increase the risk of acetaminophen toxicity. The effect of warfarin may be enhanced.
  • Interaction with Diseases: Ace XR Tablet may interact with certain diseases. Patients with alcoholism should use this medicine with caution as it may lead to serious liver injury. Individuals with a history of liver disease or current liver disease should also use the medication with caution as it can cause further liver damage. Patients with chronic malnutrition should take Ace XR tablets with great caution as it may have adverse effects.
  • Interaction with Lab Tests: Taking Ace XR Tablet may result in a false-positive result for certain tests. It is important to inform your healthcare provider about the medication you are taking before undergoing any lab tests.
  • Interaction with Food: Ace XR Tablet may slightly delay the absorption of extended-release preparations, and the rate of absorption may be decreased when taken with food high in carbohydrates.

It is essential to inform your healthcare provider about all the medications, supplements, and medical conditions you have before starting Ace XR Tablet to minimize the risk of interactions. Your healthcare provider will provide guidance on the safe and appropriate use of this medication.

Contraindications

It is contraindicated in known hypersensitivity to Paracetamol.

Pregnancy & Lactation

U.S. Food and Drug Administration (USFDA) prescribed pregnancy category B. This medicine should be used during pregnancy only if it is clearly needed.

Precautions & Warnings
  • If you are allergic to Ace XR Tablet or any of its ingredients, it is important to avoid taking it.
  • Ace XR Tablet is not recommended for children below 6 years of age. For children, alternative formulations or dosages may be available.
  • If you are pregnant or breastfeeding, it is important to consult with a physician before using Ace XR Tablet. They can assess the potential risks and benefits and provide appropriate guidance.
  • It is advisable to avoid alcohol consumption while taking Ace XR Tablet, as it may increase the risk of liver damage. Alcohol and Ace XR tablets can have additive effects on the liver.
  • If you have an impaired nutritional state caused by factors such as anorexia, wrong nutrition, alcohol abuse, or if you are dehydration, it is important to inform your doctor before taking Ace XR Tablet. These conditions may require special consideration or monitoring during the use of the medication.
  • It is important to follow the recommended doses of Ace XR Tablet and avoid exceeding them. Taking more than the recommended doses can increase the risk of serious liver damage.
Storage Conditions

Keep in a dry place away from light and heat. Keep out of the reach of children.

Frequently Asked Questions (FAQ)

Ace XR Tablet shows its effect within 30-60 minutes after administration.

The effect lasts for an average of 4-6 hours.

If you vomit within 30 minutes of taking a dose of Paracetamol tablets or syrup, it is generally recommended to retake the same dose again. This is because the medication may not have had enough time to be absorbed into your system. However, if you vomit after 30 minutes of taking the dose, you should not retake another dose until the next scheduled dose. Taking an extra dose in this case may result in taking more medication than the recommended dosage, which can be harmful.

There is no need to take this medication more than its recommended doses.

If you take this medication with the food, the reactions that took place in the body carry-outs in a much effective manner.

Yes, the Ace XR Tablet can be taken every 4 hours, but only after consulting a doctor.

You are not recommended to take Ace XR Tablet with other paracetamol containing products as it may cause paracetamol overdose.

Paracetamol is considered safe for children only when used as directed by the doctor.

No

Ace XR Tablet relieves pain by inhibiting enzymes (COX-1 and COX-2) involved in pain-causing chemical synthesis. It increases the pain threshold and reduces fever by acting on heat-regulating centers in the brain, leading to vessel relaxation, sweating, and loss of body heat.
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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