Aprocin Powder for Suspension 60ml

✔️ Dosage and Administration

The dose should be determined by the treating physician based on the type and severity of infection, susceptibility of the causative organism, patient's age and weight, and renal function.

Adults:
The usual oral dosage range is 100–750 mg twice daily, depending on the infection.

Urinary tract infections:
250–500 mg twice daily, depending on severity.

Respiratory tract infections:
250–500 mg twice daily for most upper and lower respiratory tract infections. For confirmed Streptococcus pneumoniae infection, higher doses may be required as directed by the physician.

Gonorrhoea:
A single dose may be used where appropriate according to current treatment recommendations and susceptibility.

Other infections:
500–750 mg twice daily may be used depending on the severity and type of infection.

Cystic fibrosis with pseudomonal respiratory infection:
Adults may require 750 mg twice daily under specialist supervision.

Renal impairment:
Dose adjustment may be necessary in patients with significant renal impairment. The dosage should be individualized according to renal function.

Elderly patients:
Dose selection should take renal function and other medical conditions into consideration.

Children and adolescents:
Ciprofloxacin is generally not a first-choice antibiotic in children because of concerns regarding effects on developing joints. However, it may be prescribed for specific serious infections when the expected benefits outweigh the potential risks. Pediatric dosing must be determined by a specialist.

Duration of treatment:
Treatment duration depends on the type and severity of infection, clinical response, and microbiological findings. The prescribed course should be followed exactly.

✔️ Side Effects:

• Nausea
• Diarrhoea
• Vomiting
• Dyspepsia
• Abdominal pain
• Headache
• Dizziness
• Fatigue

✔️ Drug and Food Interactions

Ciprofloxacin absorption can be significantly reduced by products containing magnesium, aluminium, calcium, iron, or zinc, as well as sucralfate.

• Take ciprofloxacin at least 2 hours before or 6 hours after these products, unless otherwise directed.
• Avoid taking ciprofloxacin at the same time as milk or yoghurt alone because absorption may be reduced.
• Calcium consumed as part of a normal meal generally has less effect on ciprofloxacin absorption.
• Ciprofloxacin may be taken with or without food unless otherwise instructed.

✔️ Pregnancy and Lactation

Ciprofloxacin is generally not recommended during pregnancy unless the physician determines that the potential benefits clearly outweigh the possible risks.

Ciprofloxacin can pass into breast milk. Breastfeeding should therefore be discussed with a healthcare professional before treatment.

✔️ Aprocin is contraindicated in patients with:

• Known hypersensitivity to ciprofloxacin or other quinolone/fluoroquinolone antibiotics.
• A previous serious allergic reaction to ciprofloxacin or another fluoroquinolone.

✔️ Aprocin should be used cautiously in patients with:

• A history of seizures or conditions that may increase seizure risk
• Central nervous system disorders
• Significant renal impairment
• Liver disease
• Diabetes or a history of blood glucose abnormalities
• A history of tendon disorders associated with quinolone use

Patients should drink adequate fluids during treatment unless fluid restriction has been medically advised.

Stop treatment and seek medical advice if symptoms such as severe rash, allergic reaction, tendon pain or swelling, severe diarrhoea, neurological symptoms, or significant changes in mental status occur.

✔️ Storage:

Store below 30°C, protected from light and moisture. Keep out of reach of children.