Insulet 30/70 Injection 10ml

✔️ Insulet 30/70 100 IU/ml Injection | Administration

• Administer by subcutaneous injection only, usually into the abdomen, upper arm, or thigh.
• Follow the prescribed timing in relation to meals. Depending on the product instructions, it is generally administered shortly before a meal.
• Rotate injection sites to reduce the risk of skin changes and lipodystrophy.
• If the product is a suspension, gently resuspend it according to the package instructions until it appears uniformly cloudy. Do not use it if the appearance remains abnormal or particles or clumps are present.
• Do not administer intravenously or intramuscularly.
• Follow the specific instructions provided with the product and by the healthcare professional.

✔️ Side Effects:

• Hypoglycaemia (low blood glucose)
• Injection-site redness, swelling, itching, or irritation
• Lipodystrophy or other changes in fatty tissue at injection sites
• Allergic reactions or skin rash
• Temporary blurred vision, particularly when blood glucose levels change
• Hypokalaemia (low potassium levels)

✔️ Contraindications

Insulet 30/70 should not be used in the following situations:

Current hypoglycaemia (low blood glucose).

Known hypersensitivity to insulin or any ingredient in the formulation.

✔️ Dosage & Administration

Adults

The dose must be individualized according to blood glucose levels, meal patterns, activity, and the patient's insulin requirements. The prescriber may adjust the dose based on regular blood glucose monitoring.

Children

The dose for children and adolescents must be determined by a qualified healthcare professional based on age, body weight, glucose readings, meals, and individual insulin requirements.

Renal and Hepatic Impairment

Patients with kidney or liver impairment may require dose adjustments because insulin requirements can change. Blood glucose should be monitored closely.

Important: The dose and timing of premixed insulin must be determined by the treating clinician. Do not start, change, or discontinue insulin independently.

✔️ Drug Interactions

Some medicines may increase or decrease insulin requirements or alter blood glucose control.

Medicines that may increase the risk of hypoglycaemia or reduce insulin requirements include:

• Other glucose-lowering medicines
• Monoamine oxidase inhibitors (MAOIs)
• Some ACE inhibitors
• Salicylates
• Sulfonamide antibiotics
• Anabolic steroids
• Alcohol

Medicines that may increase insulin requirements or raise blood glucose include:

• Corticosteroids
• Thiazide diuretics
• Thyroid hormones
• Some oral contraceptives
• Sympathomimetic medicines
• Danazol

Octreotide and lanreotide may increase or decrease insulin requirements. Beta-blockers can mask some warning signs of hypoglycaemia. Alcohol may also make blood glucose control less predictable.

✔️ Precautions and Warnings

• Monitor blood glucose regularly and follow the prescribed meal and injection schedule.
• Hypoglycaemia is a major risk and may occur if a dose is excessive, a meal is delayed or missed, or physical activity increases unexpectedly.
• Insulin requirements may decrease with kidney or liver impairment, vomiting, diarrhoea, reduced food intake, or certain hormonal disorders.
• Insulin requirements may increase during fever, infection, trauma, surgery, or some hormonal conditions.
• Changes in insulin dose, diet, exercise, or other medicines should be made with professional guidance.
• Low potassium levels (hypokalaemia) may occur, particularly in patients at increased risk.
• Pregnancy can change insulin requirements throughout gestation. Insulin treatment may also need adjustment after delivery.
• Insulin can generally be used during breastfeeding, but glucose monitoring and dose adjustment may be necessary.
• Never share insulin pens, syringes, or needles.
• Do not use the injection if it has been frozen, is expired, or does not meet the product's appearance requirements.

✔️ Storage

Store unopened insulin according to the manufacturer's instructions, generally in a refrigerator at 2°C–8°C. Do not freeze. Protect from excessive heat and direct sunlight. Storage conditions and the permitted period of use after opening depend on the specific product packaging; check the leaflet or label.