Bukof is used to relieve dry (non-productive) cough, including:
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Bukof contains Butamirate Citrate, which acts directly on the brain’s cough center to suppress coughing.
It is a non-opioid, non-sedating antitussive, unrelated to opium derivatives.
After oral administration, it is rapidly absorbed, reaching peak levels (for sustained-release form) within about 9 hours. It is highly protein-bound, with an elimination half-life of approximately 13 hours. Its active metabolites also contribute to cough suppression.
Bukof is generally well tolerated. Rare side effects may include:
These usually resolve after dose adjustment or discontinuation.
Symptoms may include:
Management includes supportive care such as activated charcoal and standard emergency treatment.
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