Contine 400 contains theophylline, a bronchodilator used to help manage respiratory conditions associated with narrowing of the airways. It helps relax the muscles of the airways, making breathing easier.
Contine 400 may be prescribed for:
It is generally used for ongoing symptom control and is not suitable for immediate relief of a sudden asthma attack.
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Theophylline helps relax the smooth muscles surrounding the airways, widening them and improving airflow. It also affects certain enzymes and chemical signalling pathways involved in airway muscle relaxation. Its effects on the heart and central nervous system mean that careful dosing and monitoring may be necessary.
Important: Theophylline has a narrow therapeutic range, meaning that the difference between an effective dose and a potentially toxic dose can be small. Dosing should be individualized by a healthcare professional, and blood-level monitoring may be required.
Take the missed dose when you remember unless it is nearly time for the next dose. If it is nearly time for the next dose, skip the missed dose and resume your regular schedule. Do not take a double dose.
Contine 400 should not be used in patients with known hypersensitivity to theophylline or other xanthine derivatives. It may also be unsuitable for people with porphyria. A healthcare professional should review the patient's medical history before treatment.
Use Contine 400 during pregnancy only when prescribed after assessing the potential benefits and risks. Theophylline passes into breast milk and may cause irritability or other effects in a nursing infant. Consult your doctor before using it while breastfeeding.
Older adults may require lower doses and closer monitoring.
Smoking can increase theophylline clearance, while stopping smoking may cause blood levels to rise. Inform your doctor about changes in smoking habits, fever, or any new medicine, as these may affect theophylline levels.
Avoid excessive caffeine from coffee, tea, energy drinks, and other sources because it may worsen side effects such as restlessness, insomnia, and palpitations. Discuss alcohol use with your healthcare professional.
Keep a prescribed rescue inhaler available if you have asthma or COPD and have been instructed to use one for sudden breathing difficulties.
Theophylline interacts with several medicines, which may increase or decrease its blood concentration.
Store according to the instructions on the product packaging. Keep away from excessive heat and moisture, and out of the reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.