Pimponil 15gm Gel

✔️ Composition of Pimponil 15gm Gel

Clindamycin Phosphate 1.2% + Tretinoin 0.025% Topical

✔️ How does Pimponil 15gm Gel work?

works by replacing damaged skin cells with newer ones, thus rejuvenating the skin. However, it may take up to three to six months to achieve noticeable results. In some cases, it might take longer, depending on the color of the post-acne inflammatory pigmentation being treated, about the normal surrounding skin.

✔️ Before using Pimponil 15gm Gel inform your doctor if you:

• Have any skin inflammation, irritation, or photosensitivity
• Have an upcoming surgery

✔️ Quick Suggestions:

✔️ Indications of Pimponil 15gm Gel

Clindamycin with Tretinoin gel is indicated for the topical treatment of acne vulgaris.

✔️ Pharmacology

Pimponil 15gm Gel combines Clindamycin phosphate, a lincosamide antibiotic, with Tretinoin, a retinoid. Clindamycin binds to the 50s ribosomal subunit of susceptible bacteria, preventing peptide chain elongation and inhibiting bacterial protein synthesis by interfering with peptidyl transfer. This action reduces the occurrence of acne by inhibiting the activity of Propionibacterium acne. Tretinoin promotes cell turnover and reduces the cohesion of follicular epithelial cells, helping to clear comedones.

✔️ Dosage & Administration of Pimponil 15gm Gel

1. Gently wash the face or affected area with warm water or mild soap.
2. Allow the skin to dry completely (approximately 30 minutes).
3. Apply a pea-sized amount of gel to your fingertip and spread it evenly over the face.

Adult Dose:

• Condition: Acne Vulgaris
• Administration: Apply a pea-sized amount of gel once daily, preferably at bedtime.
• Duration: Continue treatment for 12 weeks.

Child Dose:

• Age <12 years: Safety and efficacy not established.
• Age >12 years: Apply a pea-sized amount of gel once daily, preferably at bedtime.

✔️ Interaction

Use caution when combining with other potentially irritating topical treatments, such as medicated or abrasive soaps and cleansers, products with high alcohol content, astringents, spices, or lime. Clindamycin should not be used simultaneously with Erythromycin as their actions can be reduced when used together. When used with neuromuscular medications, the activity of these medications can be enhanced. Exercise caution when using these products together.

✔️ Contraindications

Do not use Clindamycin or Tretinoin in individuals who are hypersensitive to any component of the gel.

✔️ Pregnancy & Lactation

It is not known whether Clindamycin or Tretinoin is excreted in human milk. Use extreme caution when applying these medications to a breastfeeding mother.

✔️ Precautions & Warnings

Do not use Clindamycin with Tretinoin to treat infections of the eyes, nose, ear, lips, or on cuts or burns. Avoid direct sunlight on the treated area after application.

✔️ Storage:

Store below 25°C, away from light and moisture. Keep out of the reach of children.