Clindacin Plus Gel 15gm

✔️ Uses of Clindacin Plus Gel

Acne (pimple)

✔️ Benefits of Clindacin Plus Gel

Clindacin Plus Gel is a combination of two medicines, namely Tretinoin (vitamin A) and Clindamycin (antibiotic), primarily used to treat acne (pimples). Tretinoin is a form of vitamin A that reduces oil production in the skin, replenishes the skin, and helps keep your pores open. Clindamycin belongs to the class of antibiotics that inhibits the production of essential proteins that are necessary for bacteria to grow, multiply, and increase in numbers. Altogether it stops or slows down the growth of bacteria and prevents the growth of acne.

✔️ Side Effects of Clindacin Plus Gel

• Dermatitis
• Skin peeling
• Dryness

✔️ Quick Suggestions:

• Clean the area to be treated with water and a non-medicated soap, and let it dry for 20-30 minutes before applying the medicine.
• It may cause minor burning, stinging, or irritation when applied. Inform your doctor if this does not go away.
• Avoid contact with your eyes, nose, or mouth. Rinse it off with water if you accidentally get the cream in these areas.
• Avoid exposure to sunlight while using Clindacin Plus Gel as it increases the sensitivity of your skin. Use protective measures such as sun-cream or protective clothing.

✔️ Acne:

Acne is a common skin condition that occurs when hair follicles are blocked with dead skin cells and oil, causing pimples, whiteheads, and blackheads. Acne affects people of all ages but is most common among teenagers. Acne symptoms include pus-filled pimples, uninflamed (not swollen) blackheads, red, large, and tender bumps. The treatment for acne includes certain creams, cleansers, and antibiotics.

✔️ Overdosage of Clindacin Plus

Excessive application of Clindacin Plus Gel may cause skin irritation, redness, and dryness. If this happens, rinse your skin with warm water. If irritation persists, stop using Clindacin Plus Gel for a few days or until irritation subsides, or consult your doctor if necessary.

✔️ Pharmacology

Clindacin Plus Gel combines Clindamycin phosphate, a lincosamide antibiotic, with Tretinoin, a retinoid. Clindamycin binds to the 50s ribosomal subunit of susceptible bacteria, preventing peptide chain elongation and inhibiting bacterial protein synthesis by interfering with peptidyl transfer. This action reduces the occurrence of acne by inhibiting the activity of Propionibacterium acne. Tretinoin promotes cell turnover and reduces the cohesion of follicular epithelial cells, helping to clear comedones.

✔️ Dosage of Clindacin Plus Gel

Adult Dose:

• Condition: Acne Vulgaris
• Administration: Apply a pea-sized amount of gel once daily, preferably at bedtime.
• Duration: Continue treatment for 12 weeks.

Child Dose:

• Age <12 years: Safety and efficacy not established.
• Age >12 years: Apply a pea-sized amount of gel once daily, preferably at bedtime.

✔️ Administration of Clindacin Plus Gel

1. Gently wash the face or affected area with warm water or mild soap.
2. Allow the skin to dry completely (approximately 30 minutes).
3. Apply a pea-sized amount of gel to your fingertip and spread it evenly over the face.

✔️ Interaction

Use caution when combining with other potentially irritating topical treatments, such as medicated or abrasive soaps and cleansers, products with high alcohol content, astringents, spices, or lime. Clindamycin should not be used simultaneously with Erythromycin as their actions can be reduced when used together. When used with neuromuscular medications, the activity of these medications can be enhanced. Exercise caution when using these products together.

✔️ Contraindications

Do not use Clindamycin or Tretinoin in individuals who are hypersensitive to any component of the gel.

✔️ Pregnancy & Lactation

It is not known whether Clindamycin or Tretinoin is excreted in human milk. Use extreme caution when applying these medications to a breastfeeding mother.

✔️ Precautions & Warnings

Do not use Clindamycin with Tretinoin to treat infections of the eyes, nose, ear, lips, or on cuts or burns. Avoid direct sunlight on the treated area after application.

✔️ Storage:

Store below 25°C, away from light and moisture. Keep out of the reach of children.