Xolamid T OSD 1%+0.5% Ophthalmic Suspension 5ml

✔️ Xolamid T OSD is indicated for the reduction of elevated intraocular pressure (IOP) in:

• Open-angle glaucoma
• Ocular hypertension (OHT)

✔️ Dosage & Administration of Xolamid T OSD 1%+0.5% Ophthalmic Suspension

Adults: Instill 1 drop in the affected eye(s) twice daily

Use strictly as directed by a physician.

External use only; avoid contact with other mucous membranes (e.g., nose, mouth).

1. Wash hands thoroughly before use.
2. Tilt head back and pull down the lower eyelid.
3. Gently squeeze the bottle to instill one drop without touching the tip to the eye or surface.
4. Close eyes gently and press on the inner corner of the eye for 1 minute.

Apply gentle pressure to the tear duct for 1 minute post-instillation to prevent systemic absorption.

Pregnancy: Use only if needed.

Breastfeeding: Caution advised.

Children <18 years: Not recommended.

Elderly: Dose adjustment may not be necessary, but monitor closely.

✔️ Common Side Effects of Xolamid T OSD 1%+0.5% Ophthalmic Suspension

• Eye irritation or discomfort
• Stinging or burning sensation
• Temporary blurred vision
• Eye redness
• Metallic or altered taste (dysgeusia)

✔️ Drug Interactions

Brinzolamide:

Additive effects with oral carbonic anhydrase inhibitors or high-dose salicylates (risk of toxicity).

Timolol:

Enhanced bradycardia/hypotension with reserpine, clonidine, quinidine, or other antihypertensives.

May reduce the effect of NSAIDs.

Avoid co-use 

✔️ Contraindications

Hypersensitivity to brinzolamide, timolol, or any component

Severe respiratory or cardiac conditions, including:

• Asthma
• Severe COPD
• Sinus bradycardia
• Second or third-degree AV block
• Overt heart failure
• Cardiogenic shock
• Severe renal impairment
• Hyperchloremic acidosis
• With other ophthalmic beta-blockers or carbonic anhydrase inhibitors.

✔️ Precautions & Warnings

• Do not drive or operate machinery immediately after use due to possible blurred vision.
• Remove contact lenses before use and reinsert after 15 minutes.

Use with caution in patients with:

• Cardiac conditions (e.g., heart block, bradycardia, heart failure)
• Respiratory disorders (e.g., asthma, COPD)
• Diabetes (may mask hypoglycemia)
• Corneal problems (e.g., corneal dystrophies, diabetes-related damage)
• Thyroid disease (may mask symptoms of hyperthyroidism)

✔️ Storage

• Store below 25°C, in a cool, dry place, away from direct light.
• Discard 4 weeks after opening.