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Panpro 40 | 10 Tablets
Pantoprazole is used for the management of various acid-related gastrointestinal conditions, including:
- Peptic ulcer disease (duodenal and gastric ulcers)
- H. pylori infection (as part of combination therapy)
- Gastroesophageal reflux disease (GERD) with or without erosive esophagitis
- Zollinger-Ellison syndrome
- Oesophagitis
- Acid-related dyspepsia
- NSAID-associated ulceration
- Ulcers resistant to H2 receptor antagonists
- Stress-related GI bleeding
- Prophylaxis for acid aspiration during anesthesia
অফার মূল্য: ৳ 67
MRP:
৳
70
4%
ছাড়
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- Cash on Delivery - All over Bangladesh
- Regular Delivery: 24-48 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery: 48-96 Hours, Other Cities* Charge Tk.99-125
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✅ বিবরণ:
Pantoprazole is a substituted benzimidazole that inhibits the H+/K+ ATPase enzyme in gastric parietal cells, blocking the final step of acid secretion. It suppresses both basal and stimulated gastric acid production.
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✔️ Dosage & Administration | Panpro 40
Controlled-release: Take on an empty stomach, 1 hour before meals. Swallow whole; do not chew or crush.
Standard-release: Can be taken with or without food.
Erosive esophagitis: 40 mg once daily for 8–16 weeks; maintenance 40 mg once daily.
GERD (short-term IV): 40 mg IV once daily for 7–10 days, switch to oral when possible.
Zollinger-Ellison syndrome: 40 mg once daily PO; up to 240 mg/day in some cases. IV: 80 mg every 8–12 hours, up to 7 days.
Duodenal ulcer: 40 mg once daily for 2–4 weeks.
Gastric ulcer: 40 mg once daily for 4–8 weeks.
Pediatric Dose:
<5 years: Safety not established.
5 years (15–40 kg): 20 mg once daily for up to 8 weeks.
≥40 kg: 40 mg once daily for up to 8 weeks.
Elderly & Renal Impairment: No dosage adjustment usually needed.
Hepatic Impairment: Max 20 mg/day or 40 mg on alternate days.
✔️ Side Effects | Panpro 40
Headache (>4%), abdominal pain (4%), chest pain (4%), diarrhea (4%), rash/pruritus (4%), vomiting (>4%), constipation (<4%), facial/generalized edema (<4%)
Other possible: Angioedema, atrophic gastritis, optic neuropathy, hepatocellular damage, interstitial nephritis, pancreatitis, pancytopenia, rhabdomyolysis, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis, erythema multiforme
✔️ Contraindications:
- Concomitant use with rilpivirine, atazanavir, or nelfinavir
- Lactation
✔️ Precautions & Warnings
- Rule out gastric malignancy before therapy.
- Monitor magnesium levels during prolonged use.
- Zinc supplementation may be needed in at-risk patients receiving IV therapy.
- Pregnancy: Data show no significant risk; use only if necessary.
- Lactation: Pantoprazole is excreted in breast milk; use caution.
✔️ Drug Interactions
- May increase digoxin toxicity.
- Risk of hypomagnesemia with diuretics.
- May increase warfarin INR and prothrombin time.
- Can raise serum concentrations of methotrexate and saquinavir.
- Delayed absorption of sucralfate, ketoconazole, and itraconazole.
- May decrease efficacy of rilpivirine, atazanavir, and nelfinavir (potentially fatal).
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
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