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👁️ 1795 বার দেখা হয়েছে
Sitomet 50/1000 | 1 Strip
Sitomet 50/1000 Tablet\(Sitagliptin + Metformin Hydrochloride)
- Type 2 Diabetes Mellitus (T2DM)
- Used as an adjunct to diet and exercise to improve glycemic control.
- May be prescribed alone or with other antidiabetic agents.
- Take with meals to reduce stomach upset.
- Less likely to cause weight gain compared to some other diabetes drugs.
- Inform your doctor if you plan surgery under anesthesia.
- Report immediately if you develop deep/rapid breathing, persistent nausea/vomiting, or abdominal pain → possible lactic acidosis.
- Avoid excessive alcohol intake.
- Stay on your prescribed diet and exercise program for best results.
অফার মূল্য: ৳ 209
MRP:
৳
220
5%
ছাড়
১০০% অরিজিনাল পণ্যের নিশ্চয়তা
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Fast, Secure & Efficient Delivery
Proper Packaging
Cash on Delivery - All over Bangladesh
Regular Delivery: 24-48 Hours, Dhaka City* Charge Tk.39-59- Regular Delivery: 48-96 Hours, Other Cities* Charge Tk.99-125
ফ্রি ডেলিভারিঃ - ১৪৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে- ফ্রি ডেলিভারিঃ - ৪৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
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১০০% অরিজিনাল পণ্যের নিশ্চয়তা
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
- Cash on Delivery - All over Bangladesh
- Regular Delivery: 24-48 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery: 48-96 Hours, Other Cities* Charge Tk.99-125
- ফ্রি ডেলিভারিঃ - ১৪৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে
- ফ্রি ডেলিভারিঃ - ৪৯৯৯ টাকা+ অর্ডারে, ঢাকার
বাহিরে
- Google Play Store থেকে ডাউনলোড
- Apple Store থেকে ডাউনলোড
📲 মোবাইল অ্যাপ অর্ডারে সাশ্রয় বেশী
✅ বিবরণ:
Adults
- Initial (not on Metformin): 50 mg Sitagliptin + 500 mg Metformin twice daily.
- Already on Metformin: Continue the current metformin dose and add Sitagliptin 50 mg twice daily (100 mg/day).
- Typical adjustment: 50 mg Sitagliptin + 1000 mg Metformin twice daily if tolerated.
- Maximum daily dose: Sitagliptin 100 mg + Metformin 2000 mg.
Extended-release (XR):
Start with Sitagliptin 50–100 mg + Metformin XR 500–1000 mg once daily (preferably in the evening with food).
Gradually increase if needed.
Max: Sitagliptin 100 mg + Metformin XR 2000 mg daily.
Pediatrics
<18 years: Safety and efficacy not established.
Renal Dose Adjustment
Check eGFR before initiation.
- eGFR <30 mL/min/1.73m² → Contraindicated.
- eGFR 30–45 → Do not initiate; if already on therapy, reassess risks/benefits.
- eGFR >45 → Monitor annually; adjust as required.
Take with food to minimize stomach upset.
Swallow whole with water; do not chew, crush, or break.
Take at the same time each day for best result
প্রাসঙ্গিক পণ্য
একই জেনেরিকের বিকল্প পণ্য, গ্রাহকের আগ্রহ অনুযায়ী সাজানো
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কীভাবে অর্ডার করবেন?কীভাবে অর্ডার করবেন?
How to Orderওয়েবসাইট থেকে অর্ডার করার সহজ ভিডিও গাইড।
অ্যাপ থেকে অর্ডারের সহজ ভিডিও গাইড
অ্যাপ ডাউনলোডePharma অ্যাপ ডাউনলোড বিস্তারিত গাইড ›অ্যাপে অর্ডারের বিস্তারিত গাইডসম্পর্কিত লেখা
✔️ Mode of Action
Sitagliptin (DPP-4 inhibitor):
Increases incretin hormone activity → stimulates insulin release, reduces glucagon secretion.
Metformin (Biguanide):
Decreases hepatic glucose production.
Reduces intestinal absorption of glucose.
Improves insulin sensitivity (increases peripheral glucose uptake/utilization).
Result: Improved glycemic control by targeting multiple mechanisms.
✔️ Side Effects
Common (1–10%)
- Diarrhea (2.4%)
- Abdominal pain (2.2%)
- Hypoglycemia (esp. with insulin/sulfonylurea) (2.1%)
- Nausea (1.3%), Vomiting (1.1%)
- Headache, sore throat, nasal congestion
- Upper respiratory tract infection
Rare/Serious
- Lactic acidosis (medical emergency)
- Severe hypersensitivity (anaphylaxis, angioedema, Stevens-Johnson syndrome)
- Rhabdomyolysis
- Acute renal failure
- Exfoliative skin disorders
✔️ Drug Interactions
↑ Hypoglycemia risk: Sulfonylureas, insulin.
May worsen glycemic control: Thiazide diuretics, corticosteroids, phenothiazines, oral contraceptives, sympathomimetics, niacin, CCBs, and isoniazid.
↓ Blood glucose: ACE inhibitors.
↑ Metformin levels: Cimetidine.
Fatal risk: Iodinated contrast agents (↑ lactic acidosis risk with metformin).
✔️ Contraindications
Severe renal dysfunction (serum creatinine >1.5 mg/dL in males; >1.4 mg/dL in females).
Metabolic acidosis (including diabetic ketoacidosis).
History of serious hypersensitivity to Sitagliptin, Metformin, or excipients.
✔️ Precautions & Warnings
- Not for type 1 diabetes or diabetic ketoacidosis.
- Discontinue if pancreatitis is suspected.
- Use caution in:
- Renal or hepatic impairment.
- Hypoxic states or major surgery.
- Alcohol use (↑ risk of lactic acidosis).
- Elderly patients.
- Long-term use (may ↓ affect Vitamin B12 absorption).
Pregnancy & lactation: Use only if benefits outweigh risks
✔️ Storage:
Do not store above 30°C. Keep away from light and out of the reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
📦Pricing Information, Availability:
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