Dialon 1 Tablet 1 Strip

✔️ How does Dialon (Glimepiride) work?

Glimepiride, the active ingredient in Dialon, is a sulfonylurea that helps reduce blood glucose levels by:

• Stimulating insulin release from pancreatic beta cells.
• Increasing the sensitivity of beta cells to glucose.
• Reducing basal hepatic glucose production.
• Increasing glucose uptake in peripheral tissues.

✔️ What is the recommended dosage of Dialon?

The dosage is determined based on individual patient needs and blood glucose monitoring:

• Initial dose: 1 mg once daily before breakfast or the first main meal.
• Dose titration: Can be increased gradually at 1-2 week intervals (1 mg → 2 mg → 3 mg → 4 mg → 6 mg daily).
• Well-controlled diabetes: Usually requires 1-4 mg per day.
• Changing from other oral antidiabetics: Start with 1 mg daily, adjusting based on response.

✔️ How should Dialon be taken?

Dialon should be taken orally with a sufficient amount of liquid. The tablet should be consumed before a substantial meal to prevent hypoglycemia.

✔️ Common side effects include:

• Hypoglycaemia (low blood sugar)
• Temporary visual impairment
• Nausea, vomiting, diarrhea, abdominal pain
• Allergic reactions such as urticaria
• Drop in blood pressure

✔️ Dialon is not suitable for:

• Type I diabetes mellitus (insulin-dependent diabetes)
• Diabetic ketoacidosis or diabetic coma
• Patients with severe liver or kidney dysfunction
• Those with hypersensitivity to Glimepiride, sulfonylureas, or sulfonamides

✔️ What should I do in case of an overdose?

An overdose can lead to severe hypoglycemia.

• Mild symptoms: Consume glucose or sugar immediately and adjust the dosage or meal patterns.
• Severe reactions (coma, seizures): Seek emergency medical help. Treatment includes rapid intravenous glucose administration followed by continuous glucose infusion.

✔️ What medications can interact with Dialon?

Certain medications can either enhance or weaken the hypoglycaemic effect of Dialon:

• Increase hypoglycaemia risk: ACE inhibitors, anabolic steroids, salicylates, sulfonamide antibiotics, MAO inhibitors, fluconazole, quinolones.
• Reduce hypoglycaemic effect: Corticosteroids, diuretics, thyroid hormones, phenothiazines, rifampicin.
• Beta-blockers and clonidine: May mask hypoglycaemic symptoms.
• Alcohol: Can unpredictably potentiate or weaken Dialon’s effects.

✔️ Can Dialon be taken during pregnancy and breastfeeding?

No, Dialon should not be taken during pregnancy. Patients planning a pregnancy should switch to insulin. Dialon must also not be used while breastfeeding, as it may harm the child.

✔️ What precautions should be taken while using Dialon?

• Regular monitoring of blood glucose levels is necessary.
• Hypoglycaemia risk is higher in the initial treatment weeks.
• Avoid skipping meals after taking Dialon to prevent hypoglycemia.
• Adjust dosage in case of significant lifestyle or weight changes.

✔️ How should Dialon be stored?

• Store below 30°C.
• Keep away from direct light and moisture.
• Keep out of reach of children.