Emjard M 12.5/500mg 6pcs

✔️ How does Emjard M work?

• Empagliflozin: Inhibits the SGLT2 transporter, reducing glucose reabsorption in the kidneys and increasing glucose excretion via urine.
• Metformin: Decreases glucose production in the liver, improves insulin sensitivity, and enhances glucose uptake by muscles.

✔️ What is the recommended dosage of Emjard M?

Dosage is individualized based on patient needs and tolerability:

• Take twice daily with meals to minimize gastrointestinal side effects.
• Maximum daily dose: Metformin 2000 mg, Empagliflozin 25 mg.
• Dosage adjustments may be needed for patients switching from separate drugs or with renal impairment.

✔️ Can Emjard M be used in children?

No. Safety and effectiveness in children under 18 years have not been established.

✔️ What are the common side effects of Emjard M?

• Very common: Gastrointestinal symptoms, hypoglycemia (if used with insulin).
• Common: Genital infections, urinary tract infections, increased urination, taste disturbances, and rash.
• Rare but serious: Diabetic ketoacidosis, lactic acidosis, and Fournier’s gangrene.

✔️ Can I use Emjard M during pregnancy or breastfeeding?

• Pregnancy: Not recommended, especially during the second and third trimesters, due to potential harm to the fetus.
• Breastfeeding: Not recommended; consult your doctor for alternative treatments.

✔️ Are there any contraindications to using Emjard M?

Do not use Emjard M if you have:

• Severe renal failure (GFR <30 mL/min).
• Acute metabolic acidosis or diabetic ketoacidosis.
• Liver impairment or conditions causing tissue hypoxia.
• Alcohol intoxication or alcoholism.
• Hypersensitivity to Empagliflozin or Metformin.

✔️ Drug Interaction Guide for Empagliflozin + Metformin Hydrochloride Combination

Medications with Notable Interactions

Insulin

• Effect: Increased risk of hypoglycemia (low blood sugar).
• Recommendation: Monitor blood glucose closely and adjust insulin dose if necessary.

Sulfonylureas

• Effect: Enhanced risk of hypoglycemia.
• Recommendation: Reduce the dose of sulfonylureas and monitor for hypoglycemia.

Meglitinides

• Effect: Elevated risk of hypoglycemia.
• Recommendation: Adjust the meglitinide dose and monitor blood sugar levels carefully.

Thiazolidinediones (e.g., pioglitazone, rosiglitazone)

• Effect: Potential increased risk of heart failure.
• Recommendation: Avoid combination in patients with or at risk for heart failure.

Alpha-Glucosidase Inhibitors (e.g., acarbose, miglitol)

• Effect: Reduced effectiveness of alpha-glucosidase inhibitors.
• Recommendation: Monitor glycemic control and consider alternative therapies if needed.

Beta-Blockers

• Effect: Masking of hypoglycemia symptoms (e.g., rapid heart rate, sweating).
• Recommendation: Monitor for other signs of hypoglycemia like dizziness or confusion.

ACE Inhibitors (e.g., enalapril, lisinopril)

• Effect: Increased risk of hypotension (low blood pressure).
• Recommendation: Monitor blood pressure closely, especially during therapy initiation.

Angiotensin Receptor Blockers (ARBs, e.g., losartan, valsartan)

• Effect: Elevated risk of hypotension.
• Recommendation: Monitor for signs of dizziness or fainting, and ensure proper hydration.

Diuretics

• Effect: Increased risk of dehydration, leading to hypotension or kidney issues.
• Recommendation: Encourage adequate fluid intake and monitor for signs of dehydration.

Steroids (e.g., prednisone)

• Effect: Risk of hyperglycemia (high blood sugar).
• Recommendation: Monitor blood glucose levels and adjust diabetes medication as necessary.

Thyroid Hormones (e.g., levothyroxine)

• Effect: Risk of hypoglycemia.
• Recommendation: Monitor blood glucose and adjust thyroid hormone or diabetes medication dosage.

✔️ What should I monitor while on Emjard M?

• Kidney function (especially in elderly or volume-depleted patients).
• Signs of urinary tract or genital infections.
• Blood glucose levels to avoid hypoglycemia.
• Vitamin B12 levels annually, as Metformin may cause deficiencies.
• LDL cholesterol levels, as Empagliflozin may increase them.

✔️ What should I do in case of an overdose?

• Symptoms: Lactic acidosis (severe fatigue, abdominal pain, respiratory distress) or hypoglycemia.
• Seek immediate medical attention. Lactic acidosis is a medical emergency and may require hospitalization and dialysis.

✔️ What precautions should I take while using Emjard M?

• Ensure adequate hydration to avoid dehydration and hypotension.
• Discontinue temporarily during acute illness or when undergoing contrast imaging procedures.
• Report any symptoms of ketoacidosis, urinary tract infections, or severe hypoglycemia.
• Always consult with your healthcare provider before starting or stopping any medication.
• Maintain close monitoring of blood glucose levels during combined therapy with any interacting drugs.
• Inform your doctor of all medications and supplements you are taking to avoid adverse interactions.

✔️ How should Emjard M be stored?

• Store below 30°C in a dry place, away from light and moisture.
• Keep out of reach of children.