Taflopres contains tafluprost, a prostaglandin analogue, and timolol maleate, a non-selective beta-adrenergic receptor blocker.
Tafluprost selectively activates FP prostanoid receptors, increasing the drainage of aqueous humour through the uveoscleral pathway and thereby lowering intraocular pressure.
Timolol reduces the production of aqueous humour in the eye. Although its precise mechanism of action in lowering eye pressure is not fully understood, this reduction in fluid production helps decrease intraocular pressure.
The combined action of these two ingredients helps control elevated eye pressure more effectively.
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Taflopres ophthalmic solution is used to reduce elevated intraocular pressure (IOP) in patients with open-angle glaucoma or ocular hypertension. Lowering eye pressure helps reduce the risk of glaucoma-related damage to the optic nerve.
Instil one drop into the affected eye once daily in the evening, or as directed by an ophthalmologist.
Follow the prescribed dosing schedule. Do not exceed the recommended frequency of administration.
Specific interaction studies have not been conducted for this combination. Inform your doctor about all medicines you are using, particularly other eye drops, beta-blockers, and medicines that affect heart rate or blood pressure.
Taflopres is contraindicated in patients with known hypersensitivity to tafluprost, timolol, or any other ingredient in the formulation.
The most frequently reported treatment-related adverse effect is eye redness (ocular hyperemia).
Other possible side effects include:
Consult an ophthalmologist if side effects persist, worsen, or interfere with daily activities.
Pregnancy: Adequate, well-controlled studies in pregnant women are lacking. Taflopres should be used during pregnancy only when the potential benefits justify the possible risks to the fetus, as determined by a healthcare professional.
Breastfeeding: It is not known whether tafluprost, timolol, or their metabolites pass into human breast milk. Caution is advised when prescribing this medicine to breastfeeding women. Consult your doctor before use.
Store in a cool, dry place, protected from light. Keep out of reach of children. Follow the manufacturer's instructions regarding storage after opening.
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