Aprodex Ear & Eye 0.3%+0.1% Drops 5ml

✔️ Dosage & Administration | Dexamethasone + Ciprofloxacin Eye & Ear Drops

For Eye

Instill 1 drop into the affected conjunctival sac every 4–6 hours.

For more severe inflammation, the frequency may be increased to 1 drop every 2 hours during the first 24–48 hours, followed by a reduction in frequency as the condition improves, according to medical advice.

For Ear

Acute otitis media in children with tympanostomy tubes:
Instill 4 drops into the affected ear twice daily for 7 days.

Acute otitis externa:
Instill 4 drops into the affected ear twice daily for 7 days.

Pediatric use: Safety and effectiveness in children below 1 year of age have not been established.

Shake the bottle well before use. Avoid touching the dropper tip to the eye, ear, skin, or other surfaces to prevent contamination.

✔️ Side Effects: Dexamethasone + Ciprofloxacin Eye & Ear Drops

Eye:
Possible adverse effects include:

• Temporary burning or discomfort
• Stinging
• Redness
• Itching
• Foreign-body sensation
• Excessive tearing
• Dryness
• Photophobia
• Blurred vision
• Eye pain
• Conjunctivitis or keratitis
• Periocular or facial swelling

Prolonged use of the steroid component may increase intraocular pressure and may contribute to glaucoma, optic nerve damage, posterior subcapsular cataract, and delayed wound healing.

Ear:
Possible side effects include:

• Ear discomfort
• Ear pain
• Irritability
• Dizziness
• Redness or erythema

✔️ This medicine should not be used in patients with:

• Known hypersensitivity to ciprofloxacin, dexamethasone, or any component of the preparation
• Herpes simplex or other viral infections of the eye
• Fungal infections of the eye or ear
• Mycotic infections of ocular or auricular structures
• Glaucoma
• Newborn infants

✔️ Pregnancy & Lactation

Pregnancy: Adequate, well-controlled studies in pregnant women are unavailable. This medicine should be used during pregnancy only when the expected benefits outweigh the potential risks to the fetus and under medical supervision.

Breastfeeding: It is not known whether the active ingredients are excreted into human breast milk. A healthcare professional should assess the benefits and potential risks before use during breastfeeding.

✔️ Drug Interactions

Specific interaction studies with topical ophthalmic ciprofloxacin and dexamethasone have not been established. However, systemic quinolones may interact with certain medicines, including theophylline, caffeine, warfarin and its derivatives, and cyclosporine.

Although systemic exposure from topical eye or ear administration is generally much lower, inform your doctor about all medicines you are taking.

✔️ Precautions & Warnings

• Prolonged topical steroid use may increase intraocular pressure and can lead to glaucoma, optic nerve damage, visual field changes, or posterior subcapsular cataract.
• Monitor intraocular pressure when treatment is prolonged.
• Long-term steroid use may increase the risk of fungal infection of the cornea, particularly in patients with persistent corneal ulceration.
• Prolonged antibiotic use may lead to the overgrowth of organisms that are not susceptible to ciprofloxacin.
• If the condition worsens or fails to improve, medical evaluation is required.
• Do not use the preparation for longer than prescribed.
• Avoid contaminating the dropper tip during administration.

✔️ Storage:

• Shake well before each use.
• Keep the bottle tightly closed immediately after administration.
• Use within 30 days after first opening.
• Do not use the product after the recommended period following opening.
• Store in a cool, dry place away from direct light and keep out of reach of children.