Zaveg 10mg Nasal Spray

✔️ The recommended dose is:

10 mg as a single spray into one nostril, taken as needed for an acute migraine attack.

• Do not administer more than one spray (10 mg) within 24 hours.
• The safety of treating more than 8 migraine attacks within 30 days has not been established.
• Use only as directed by your doctor.

✔️ Side Effects

• Taste disturbances
• Nausea
• Nasal discomfort
• Vomiting

✔️ Drug Interaction

Zavegepant may interact with medicines that affect specific drug transporters.

• Avoid concomitant use with medicines that inhibit OATP1B3 or NTCP transporters.
• Avoid concomitant use with medicines that induce OATP1B3 or NTCP transporters.
• Avoid using intranasal decongestants together with Zaveg. If an intranasal decongestant is necessary, it should be administered at least 1 hour after Zaveg, as directed by a healthcare professional.
• Inform your doctor about all prescription medicines, over-the-counter medicines, vitamins, and supplements you are taking.

✔️ Zaveg Nasal Spray is contraindicated in patients with:

• A known history of hypersensitivity to zavegepant
• Hypersensitivity to any component of the formulation

✔️ Precautions & Warnings

Hypersensitivity Reactions

Serious hypersensitivity reactions, including facial swelling and urticaria, may occur. If a serious allergic reaction develops, discontinue Zaveg and seek immediate medical attention.

Hypertension

New-onset or worsening hypertension may occur during treatment. Patients with a history of high blood pressure should inform their doctor and have their blood pressure monitored when appropriate.

Raynaud's Phenomenon

Zavegepant may cause new-onset or worsening of pre-existing Raynaud's phenomenon. Patients who develop symptoms such as unusual coldness, numbness, pain, or color changes in the fingers or toes should contact their healthcare professional.

✔️ Pregnancy & Lactation

Pregnancy

There are insufficient human data to determine the developmental risks associated with zavegepant use during pregnancy.

Animal studies did not demonstrate adverse effects on fetal development following subcutaneous administration at exposures higher than those achieved with clinical use.

Zaveg should be used during pregnancy only when considered necessary by a healthcare professional after weighing the potential benefits and risks.

Lactation

It is not known whether zavegepant or its metabolites are present in human breast milk, or whether zavegepant affects milk production or the breastfed infant.

The benefits of breastfeeding should be considered together with the mother's clinical need for zavegepant and any potential risks to the breastfed infant.

Consult your doctor before using Zaveg while breastfeeding.

✔️ Storage:

• Store below 30°C.
• Protect from light and moisture.
• Keep the nasal spray in its original container.
• Keep out of the reach of children.
• Do not use after the expiry date