Sulprex HFA Refill | (100mcg+20mcg)/puff

✔️ Overdose & Possible Side Effects

Overdose
Most likely due to the Salbutamol component, symptoms may include chest pain (angina), high blood pressure, low potassium (hypokalemia), and rapid heartbeat (tachycardia).

Possible Side Effects

From Salbutamol: mild tremor, headache (usually resolves with continued use), rare muscle cramps, allergic reactions (angioedema, urticaria, bronchospasm, hypotension).

From Ipratropium bromide: rare headache, flu-like symptoms, chest pain, nausea, difficulty breathing, cough, throat irritation, sinusitis.

✔️ Dosage & Administration

Adults (including the elderly): 2 puffs, four times daily.

Extra puffs may be taken if needed, but do not exceed 12 puffs in 24 hours.

Follow the prescribing doctor’s instructions carefully.
(Use only under the guidance of a registered physician.)

Administration Guidelines
Using an inhaler properly is crucial; incorrect technique can lead to less medicine reaching the lungs. Correct use helps prevent or reduce the severity of asthma or COPD attacks.

Recommended steps (as per the National Asthma Guidelines):

1. Remove the cap from the inhaler.
2. Shake the inhaler vigorously at least six times before use.
3. If new or unused for over a week, shake and release one test puff into the air.
4. Breathe out fully and hold the inhaler upright.
5. Place the mouthpiece between your teeth, closing your lips tightly around it.
6. Start inhaling slowly and deeply through your mouth while pressing down firmly on the canister to release the medicine.
7. Remove the inhaler and hold your breath for at least 10 seconds (or as long as comfortable).
8. If a second puff is prescribed, wait 1 minute before repeating steps 4–7.
9. Replace the cap and rinse your mouth with water after use.

Technique check: Use a mirror occasionally; if you see white mist escaping, your lips may not be sealed or you may be pressing too early/late—repeat correctly.

Cleaning: Once a week, remove the metal canister, rinse the plastic actuator and cap in warm water (never immerse the canister in water), dry thoroughly, and reassemble.

✔️ Drug Interactions

Sulprex can be used alongside other COPD medicines such as sympathomimetic bronchodilators, methylxanthines, and steroids, but caution is advised:

Use carefully with other anticholinergic agents or sympathomimetic drugs to avoid excessive cardiovascular side effects.

Beta-2 agonists like Salbutamol should be used cautiously with non–non-potassium-sparing diuretics, monoamine oxidase inhibitors, or tricyclic antidepressants due to possible interactions.

✔️ Contraindications

Allergy to Soya-lecithin, soybean, peanut, or related food products.

Hypersensitivity to atropine (or its derivatives) or any components of the product.

✔️ Pregnancy & Lactation

Ipratropium bromide: Pregnancy category B (animal studies show no harm to fetus).

Salbutamol: Pregnancy category C (animal studies show teratogenic effects).

Use in pregnancy only if potential benefits outweigh risks. Unknown if excreted in human milk; caution is advised for breastfeeding mothers.

✔️ Storage

• Keep away from heat, sunlight, and children.
• Do not puncture, burn, or expose the canister to high temperatures, even when empty.
• Store in a cool, dry place.
• Keep away from the eyes.