Lole-SM Lotion 30ml Tube

✔️ Uses of Lole-SM Lotion

Fungal Infection

✔️ How does Lole-SM Lotion work?

Luliconazole is an antifungal medication that treats skin infections. It works by killing the fungi on the skin by destroying their cell membrane. This treats your skin infection.

✔️ Quick Suggestions:

• Lole-SM Lotion helps treat skin infections caused by many different types of fungi.
• Apply an amount sufficient to cover the affected area and 1 inch of the immediate surrounding skin.
• It can take a few weeks for the infection to clear and a few months before the skin returns to its normal color.
• Finish the full course of treatment even if you feel better.
• It is not taken orally, so it does not cause many side effects.
• Avoid getting it in the eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water.
• Inform your doctor if the infection has not cleared up after four weeks of treatment.

✔️ Few healthy tips for Athlete's Foot

• Keep your feet clean and dry, particularly between the toes.
• Cut your nails short and prefer open-toe shoes for everyday use.
• Use a separate clean towel for the feet and wear clean cotton socks.
• Never share your socks, shoes, and towel with others.

✔️ Side Effects: Lole-SM Lotion

Application site irritation, Itching, Skin exfoliation

✔️ Benefits: Lole-SM Lotion

• Luliconazole + Terbinafine targets the fungal cell membrane, which is vital for the fungus's survival.
• It works by inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane.
• This disruption weakens the membrane, preventing the entry of harmful substances and causing the leakage of cellular contents, ultimately leading to the death of the fungus.

✔️ Directions for Using Lole-SM Lotion

• Apply once or twice daily as advised by your doctor.
• Thoroughly cleanse and dry the affected areas before application.
• Apply a thin layer of the cream to the affected skin and the surrounding area.
• Rub gently until it is absorbed.
• For areas such as under the breasts (submammary), between fingers or toes (interdigital), in the groin (inguinal), or between buttocks (intergluteal), the cream can be covered with a gauze strip, especially at night, to enhance absorption.

✔️ Duration of Treatment: Lole-SM Lotion

• Tinea corporis (ringworm of the body): 1 to 2 weeks.
• Tinea cruris (jock itch): 1 to 2 weeks.
• Tinea pedis (athlete's foot): 1 week.
• Cutaneous candidiasis (skin yeast infections): 2 weeks.
• Pityriasis versicolor (a type of skin discoloration): 2 weeks.

✔️ Symptom Relief:

• Clinical symptoms often improve within a few days of starting treatment.
• Irregular use or premature discontinuation can lead to a recurrence of the infection

✔️ Conditions Treated by Lole-SM Lotion

Fungal Nail Infections (Onychomycosis)

• Fungal nail infections are caused by fungi from the environment entering the nail through small cracks in the nail or surrounding skin.
• Symptoms:
  • Thickened, discolored nails (yellow, white, or brown).
  • Increased nail fragility.
  • Usually painless unless the infection becomes severe.
• Prevalence: Toenail infections are more common than fingernail infections.

Tinea Capitis (Scalp Ringworm)

• A contagious fungal infection affects both the scalp and hair.
• Symptoms:
  • Dry, itchy, and scaly patches on the scalp.
  • Hair loss in affected areas.
  • Redness and circular patches resembling a ring, hence the name "ringworm."
• Demographics: Most common in children aged 3 to 7 years.

✔️ Interaction

Luliconazole + Terbinafine has been identified as an inhibitor of the CYP450 2D6 enzyme, which metabolizes several drugs. Co-administration with terbinafine may alter the metabolism of these drugs, requiring careful monitoring and possible dose adjustments. Affected drug classes include:

• Tricyclic antidepressants (e.g., amitriptyline, nortriptyline)
• Selective serotonin reuptake inhibitors (SSRIs)
• Beta-blockers
• Class 1C antiarrhythmics (e.g., flecainide, propafenone)
• Monoamine oxidase inhibitors (MAOIs) Type B

Monitor patients closely when terbinafine is prescribed alongside these medications, as reduced clearance of these drugs could lead to increased side effects.

✔️ Contraindications

Hypersensitivity

✔️ Storage:

Store in a cool and dry place away from sunlight