Cilostazol is a selective and reversible phosphodiesterase-III (PDE-III) inhibitor. By inhibiting PDE-III, it increases cyclic AMP (cAMP) levels in platelets and blood vessels. This action helps prevent platelet aggregation and promotes vasodilation, resulting in improved blood circulation, especially in the lower extremities.
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Cilosta 100 is prescribed for the management of intermittent claudication, a condition caused by reduced blood circulation to the legs. It helps relieve symptoms such as leg pain, cramping, numbness, and weakness that occur during walking by improving blood flow to the lower limbs. Cilosta 100 widens blood vessels and reduces platelet stickiness, thereby improving blood flow to the legs and reducing symptoms associated with poor circulation.
Patients should continue taking the medicine regularly as prescribed. Symptom improvement may take up to 12 weeks.
The medicine may increase the risk of bleeding. Contact your doctor immediately if you notice:
Avoid driving or operating machinery if dizziness occurs.
Caution is advised when used with medications affecting CYP3A4 or CYP2C19 enzymes, including:
These drugs may alter the blood levels and effectiveness of cilostazol.
Store in a cool, dry place away from heat and moisture. Keep out of reach of children.
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