Coralcin DX 1 Strip

✔️ Composition:

• Coralcin Tablet: Calcium Carbonate USP 1250 mg (from coral), equivalent to 500 mg elemental Calcium + Vitamin D USP 200 IU
• Coralcin-DX Tablet: Calcium Carbonate USP 1500 mg (from coral), equivalent to 600 mg elemental Calcium + Vitamin D USP 400 IU
• Effervescent Tablet: Calcium Carbonate USP 1500 mg (from coral), equivalent to 600 mg elemental Calcium + Vitamin D3 400 IU (as Cholecalciferol)

✔️ Dosage & Administration:

• Take 1 tablet once or twice daily with sufficient water.
• Best absorbed when taken with food.
• For effervescent tablet: Dissolve in a glass of water, stir, and drink immediately.

✔️ Drug Interactions:

• Thiazide diuretics: Risk of hypercalcaemia – monitor calcium levels.
• Steroids: May reduce calcium absorption.
• Cholestyramine, paraffin oil: May reduce vitamin D absorption.
• Tetracyclines, bisphosphonates, fluoride: Separate dosing to avoid absorption interference.
• Cardiac glycosides (e.g., digoxin): Monitor ECG and calcium levels.
• Foods rich in oxalates/phytates (e.g., spinach, whole grains): Avoid within 2 hours of intake.

✔️ Side Effects:

• Gastrointestinal discomfort (e.g., constipation, nausea)
• Rare allergic reactions, hypercalcemia symptoms
• Vitamin D-related: occasional skin rashes

✔️ Contraindications:

• Hypercalcemia, hyperparathyroidism
• Nephrolithiasis, hypercalciuria
• Severe renal impairment
• Hypersensitivity to ingredients
• Caution with digoxin therapy

✔️ Use in Pregnancy & Lactation:

Safe within recommended limits (≤1500 mg Calcium, ≤600 IU Vitamin D daily)

Both Calcium and Vitamin D3 pass into breast milk – monitor infant supplementation accordingly

✔️ Precautions:

• Monitor serum calcium and renal function in long-term use
• Use caution in patients with renal impairment, sarcoidosis, immobilization, or vitamin D-containing medications
• Risk of soft tissue calcification in susceptible patients

✔️ Overdose:

• May lead to hypervitaminosis D and hypercalcaemia
• Symptoms: vomiting, constipation, confusion, cardiac irregularities, coma (in severe cases)
• Treatment: stop intake, rehydrate, use diuretics/bisphosphonates/calcitonin/steroids as needed; monitor renal and cardiac function

✔️ Storage:

Keep below 30°C, away from light and moisture. Store out of children's reach.