Moxacil 875mg 6pcs

Indications of Moxacil 875

Moxacil 875 Tablet is used to treat infections caused by bacteria that are vulnerable to the ß-lactamase enzyme. These infections include the following:

• Infections of the ears, nose, and throat (i.e. otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis)
• Infections of the lower respiratory tract (i.e. pneumonia, acute and chronic bronchitis lung abscess, empyema, bronchiectasis)
• Infections affecting the skin and soft tissues (i.e. cellulitis, carbuncles, furunculosis, infected wounds, abscess)
• Infections of the genito-urinary tract (i.e. pyelonephritis, cystitis and urethritis)
• Venereal illness is a type of venereal infection (i.e. acute uncomplicated gonorrhea)
• It is used as a short-term treatment for tooth abscesses.
• It's also used in combination with Clarithromycin and Lansoprazole (called triple therapy) to treat H. pylori infection and duodenal ulcer illness, as well as to limit the chance of recurrence of the ulcer.

Pharmacology of Moxacil 875

Amoxicillin is a penicillin with a broad spectrum of activity. It works against a variety of Gram-positive and Gram-negative bacteria. It works by preventing the biosynthesis of cell walls. In the presence of stomach acid, amoxicillin is stable and is readily absorbed after oral administration. Amoxicillin reaches its maximal plasma concentration about 1 to 2 hours after an oral dose. Amoxicillin is widely disseminated in human tissues and fluids at various concentrations.

Dosage & Administration 

• Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections.
  
  Children (up to 10 years of age) : 125 mg three times daily, increasing up to 250 mg three times daily for severe infections.
• Severe or recurrent purulent respiratory infection: 3 gm every 12 hours.
• Otitis media: The recommended dose is 1 g three times daily for adults and 40 mg/kg body weight daily in 3 divided doses for children (max. 3 g daily).
• Pneumonia: The recommended dose is 500-1000 mg three times daily.
• Dental abscess: The recommended dose is 3 gm, repeated after 10-12 hours.
• Urinary tract infections: The recommended dose is 3 gm, repeated after 10-12 hours.
• Gonorrhoea: Single dose of 2-3 gm with Probenecid 1 gm is recommended (Probenecid is contraindicated in children under 2 years).
• In renal impairment: it may be necessary to reduce the total daily dosage.

Interaction of Moxacil 875

When you take Amoxicillin and Probenecid together, your blood levels of Amoxicillin may rise and stay high for a long time. Amoxicillin may alter gut flora, resulting in decreased estrogen reabsorption and decreased efficacy of combined estrogen/progesterone contraceptives.

Contraindications          

Amoxicillin is not recommended for people who are allergic to penicillin.

Side Effects of Moxacil 875

The side effects are minor and only last a short time. Diarrhea, indigestion, and rash are all possible symptoms. Only a few cases of pseudo-membranous colitis have been reported.

Pregnancy & Lactation

Amoxicillin is classified as a pregnancy category B by the US Food and Drug Administration. However, no suitable and well-controlled studies on pregnant women have been conducted. Because animal reproduction studies do not always predict human response, this medication should only be used during pregnancy if absolutely necessary. Human milk has been found to contain amoxicillin. When administering Amoxicillin to a nursing mother, caution should be exercised.

Precautions & Warnings

During treatment, keep in mind the likelihood of superinfection with mycotic or bacterial diseases. If superinfections develop, Amoxicillin should be stopped and appropriate treatment started. If acidosis is suspected, discontinue this tablet and hospitalize the patient immediately.

Regular monitoring of thyroid-stimulating hormone (TSH) levels is recommended in patients with hypothyroidism.

Long-term treatment with metformin has been associated with a decrease in vitamin B12 serum levels which may cause peripheral neuropathy. Monitoring of the vitamin B12 level is recommended.

Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.