Coralcin DV 500mg+400IU Tablet (Pot)

✔️ Coralcin-DV tablets are used for both the prevention and treatment of:

• Osteoporosis
• Osteomalacia
• Tetany
• Hypoparathyroidism
• Bone development disorders

Additionally, it serves as a supplement for individuals with inadequate calcium intake, including children, pregnant and lactating women, elderly individuals, and those with rickets. Other uses include managing pancreatitis and acting as a phosphate binder in chronic kidney disease.

✔️ Dosage & Administration

Regular tablets: Take one tablet once or twice daily with plenty of water or as prescribed by a physician. Taking it with food improves absorption.

✔️ Side Effects of Coralcin DV

• Gastrointestinal irritation, including constipation
• Hypercalcemia (rare, but may occur in chronic kidney disease)
• Allergic reactions, irregular heartbeat, nausea, vomiting, dry mouth, and drowsiness
• Occasional skin rash due to Vitamin D supplementation

✔️ Drug Interactions

• Thiazide diuretics: May reduce calcium excretion, increasing hypercalcemia risk. Regular monitoring is advised.
• Corticosteroids: Can decrease calcium absorption, requiring dose adjustments.
• Cholestyramine and certain laxatives: May reduce Vitamin D absorption.
• Tetracycline antibiotics: Calcium can hinder absorption. Take these medications 2 hours before or 4–6 hours after calcium intake.
• Cardiac glycosides (e.g., Digoxin): High calcium levels may increase toxicity, necessitating ECG and serum calcium monitoring.
• Bisphosphonates and sodium fluoride: Take Coralcin-DV at least 3 hours before these medications to prevent reduced absorption.
• Oxalic acid (spinach, rhubarb) & phytic acid (whole grains): Can inhibit calcium absorption; avoid taking calcium supplements within 2 hours of consuming these foods.

✔️ Avoid use in: Coralcin DV

• Hypercalcemia or hyperparathyroidism
• Hypercalciuria or kidney stones
• Severe kidney disease
• Hypersensitivity to any ingredients
• Patients on Digoxin (requires careful monitoring)

✔️ Overdose Effects of Coralcin DV

Excess calcium and Vitamin D intake may result in hypercalcemia and hypervitaminosis D, causing:

• Nausea, vomiting, constipation, thirst, muscle weakness, mental disturbances
• Severe cases: Kidney damage, soft tissue calcification, cardiac arrhythmias, coma, or death

Discontinue calcium, rehydrate, and consider diuretics, bisphosphonates, calcitonin, or corticosteroids based on severity. Monitor electrolytes, kidney function, and ECG.

✔️ Pregnancy & Lactation

Pregnant women should not exceed 1500 mg of Calcium and 600 IU of Vitamin D daily. High doses may harm the fetus.

No evidence suggests that Vitamin D at therapeutic levels is harmful during pregnancy.

Safe during breastfeeding, but Vitamin D passes into breast milk, so additional supplementation should be carefully considered.

✔️ Precautions & Warnings

• Long-term use requires monitoring of serum calcium levels and kidney function (especially in elderly patients and those on diuretics).
• Vitamin D should be used cautiously in those with kidney impairment to prevent calcium buildup in soft tissues.
• Patients with sarcoidosis may have increased Vitamin D metabolism, requiring close monitoring of calcium levels.
• Immobilized osteoporosis patients have a higher risk of hypercalcemia and require supervision.
• Caution when combining with other Vitamin D-containing medications to avoid overdose.

✔️ Storage Conditions

• Store below 30°C, away from light and moisture.
• Keep out of reach of children.