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Home Medicines Cancer/oncology Ovarib 100mg Tablet 1 Strip

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Ovarib 100mg Tablet 1 Strip

Name: Ovarib 100mg Tablet 1 Strip
Brand: Renata Limited
SKU: 7120
Price: 3000 BDT
Availability: InStock

Renata Limited

Generic: Olaparib

Type: Tablet

Pack Size: 6 Pcs

Tablet

6 Pcs

৳ 3000 ৳ 2940

Olaparib-

Breast Cancer:
Ovarib is approved as monotherapy for adult patients with HER2-negative metastatic breast cancer harboring confirmed or suspected harmful germline BRCA mutations (gBRCAm). Candidates should have previously undergone chemotherapy in the neoadjuvant, adjuvant, or metastatic setting. For hormone receptor-positive cases, disease progression during or unsuitability for endocrine therapy must be confirmed.

Ovarian Cancer:
Indicated for maintenance therapy in adult patients with platinum-sensitive relapsed (PSR) high-grade epithelial ovarian, fallopian tube, or primary peritoneal cancer who have achieved a complete or partial response to platinum-based chemotherapy.

Discount Price: ৳ 2,940

MRP: ৳ 3000 2% Off

🎉 Save ৳: 60 in this Product

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Regular Delivery: 24-48 Hours, Dhaka City* Charge Tk.39-59
Regular Delivery: 48-96 Hours, Other Cities* Charge Tk.99-125

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✅ Description:

Olaparib is a PARP (poly ADP-ribose polymerase) enzyme inhibitor targeting PARP1, PARP2, and PARP3, which are involved in DNA repair, transcription, and cell cycle control. Inhibiting these enzymes, particularly in BRCA-deficient cells, induces DNA damage and promotes the death of cancer cells. Preclinical studies demonstrate tumor suppression in models both alone and after platinum chemotherapy.

Absorption: Rapid; peak levels in 1–3 hours post-dose. High-fat meals delay peak time by ~2 hours but only modestly increase overall exposure (~20% increase in AUC).

Distribution: Mean volume of distribution ~167 L. Plasma protein binding ~82%.

Metabolism: Mainly via CYP3A4/5. The majority of the circulating drug is unchanged Olaparib. Extensively metabolized to oxidized and conjugated forms.

Excretion: Half-life ~12 hours. ~44% eliminated via urine and 42% via feces, mostly as metabolites.

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Specialist Doctors Near You

ONCOLOGY · MEDICINE · GP

DR. FERDOUS SHAHRIAR SAYED

M- PHIL, MD, MBBS

ONCOLOGY

📍 Evercare Hospital , Plot-81, Block-E, Bashundhara R/A, Dhaka-1247

Major Hospital

Chamber Phone

1915489901

MD.SALIM REZA

MBBS, DMRT, FCPS

ONCOLOGY

📍 Square Hospital, Panthopath, Dhaka

Major Hospital

Chamber Phone

1711608304

Tasneem Hossain

MBBS, MD ( Oncology)

ONCOLOGY

📍 Popular Diagnostic Centre Ltd. (Jatrabari)

Major Hospital

Chamber Phone

None

DR. SYED MUHAMMAD AKRAM HUSSAIN

FCPS

ONCOLOGY

📍 Square Hospital, Panthopath, Dhaka

Major Hospital

Chamber Phone

1611594747

PARVIN AKHTER BANU

FCPS

ONCOLOGY

📍 Labaid Cancer Hospital, 26,Green Road,Dhanmondi, Dhaka.

Major Hospital

Chamber Phone

01817505430

✔️ Dosage & Administration

Recommended Dose: 400 mg (eight 50 mg capsules) twice daily (total 800 mg/day), with or without food. Continue until disease progression or intolerable toxicity.

Missed Dose: If you miss a dose, skip it and take the next scheduled dose. Do not double-dose.

Administration Notes: Swallow capsules whole; do not chew, dissolve, or open.

Dose Adjustments:

Adverse Reactions:

1st reduction: 200 mg twice daily
2nd reduction: 100 mg twice daily

With CYP3A Inhibitors:

Strong inhibitors: 150 mg twice daily
Moderate inhibitors: 200 mg twice daily

Renal Impairment:

Mild: No adjustment needed
Moderate: 300 mg twice daily
Severe: Not studied

✔️ Side Effects

Common Serious ADRs: Anemia (2.4%), neutropenia, and thrombocytopenia.

Discontinuation Rate: 4.9% in Ovarib arm vs 7.7% with chemotherapy.

Other Effects: Fatigue, nausea, vomiting, loss of appetite, diarrhea.

✔️ Interactions

Increased Levels: Strong CYP3A inhibitors (e.g., itraconazole) can significantly raise Olaparib levels. Avoid co-use; reduce dose if unavoidable. Also, avoid grapefruit and Seville oranges.

Decreased Levels: Strong CYP3A inducers (e.g., rifampicin) may lower efficacy by reducing plasma levels. Avoid co-administration.

✔️ Contraindications

Known hypersensitivity to Olaparib or any component of the formulation.

✔️ Use in Pregnancy & Lactation

Pregnancy: May harm the fetus based on the mechanism and animal studies. Avoid during pregnancy.

Lactation: Unknown if excreted in breast milk. Breastfeeding is not recommended during treatment.

✔️ Precautions & Warnings

MDS/AML Risk: <1.5% incidence. Monitor CBC at baseline and monthly. Discontinue if confirmed.

Pneumonitis: Rare but potentially fatal. Discontinue if confirmed and manage appropriately.

✔️ Storage:

Store below 30°C in a dry place away from light. Keep out of reach of children.

Frequently Asked Questions (FAQ)

+ Q. What is the price of Ovarib 100mg Tablet 1 Strip in Bangladesh?

The latest Ovarib 100mg Tablet 1 Strip price in Bangladesh is shown on this page. Price may change depending on stock, pack size, and active offers.

+ Q. Can I buy Ovarib 100mg Tablet 1 Strip online from ePharma?

Yes, you can order Ovarib 100mg Tablet 1 Strip online from ePharma when it is available in stock. Delivery options depend on your location in Bangladesh.

+ Q. Does Ovarib 100mg Tablet 1 Strip require a prescription?

Prescription requirements can vary by product type. Please follow the product label and consult a qualified healthcare professional when needed.

+ Q. Who is the manufacturer of Ovarib 100mg Tablet 1 Strip?

Ovarib 100mg Tablet 1 Strip is from Renata Limited. Please check the product details section for updated manufacturer and product information.

+ Q. What is the pack size of Ovarib 100mg Tablet 1 Strip?

The listed pack size for Ovarib 100mg Tablet 1 Strip is 6 Pcs.

Check our pricing section for Ovarib 100mg Tablet 1 Strip price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

⚠️Disclaimer:

At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:

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