Nebanol Plus Ointment 10gm

Indications of Nebanol Plus 10 Ointment

It is a combination drug called Nebanol Plus. It is used to treat different fungus-related skin infections. By combating the infection-causing microorganisms, it reduces skin infection symptoms like redness, swelling, itching, etc. Nebanol Plus should only be applied externally, and you should follow your doctor's instructions.

Pharmacology of Nebanol Plus 10 Ointment

The ideal topical antibacterial arrangement is most closely achieved by Polymyxin B sulfate, Neomycin, and Bacitracin zinc. The three anti-microbials are bactericidal, and their range of activity essentially encompasses all pathogenic microbes discovered topically. When applied topically, Polymyxin B sulfate with Neomycin and Bacitracin zinc may occasionally cause chafing, but skin or mucous layer retention is of little consequence. Gram-negative bacteria, including clinically isolated strains of Pseudomonas aeruginosa, are attacked by polymyxin B sulfate. This living thing is conspicuously absent from the spectrum of the majority of other anti-microbial agents, but it is utterly defenseless against polymyxin B sulfate, which is acknowledged as the most effective agent for the treatment and prevention of Pseudomonas diseases. Neomycin exhibits bactericidal activity against a variety of gram-positive and gram-negative organisms, including numerous Proteus strains. According to various experts, neomycin is the most potent anti-microbial against Staphylococcus aureus, one of the more prevalent aetiological organisms in topical bacterial diseases. Bacitracin zinc extends the range of this treatment's antibacterial activity to include hemolytic streptococci and is incredibly effective against gram-positive bacilli and cocci. These three anti-microbials overlap their bactericidal spectra, resulting in increased movement due to their combined anti-microbial activity.

Dosage & Administration of Nebanol Plus 10 Ointment

Nebanol Plus® Ointment should be applied thinly over the affected area after cleaning it. 1-3 daily applications should be continued until the infection is controlled and healing completely.

Children and Infants Nebanol Plus® Ointment is suitable for use in children at the same dose as adults, but the dose should be reduced in infants. This ointment is not recommended for use in neonates.

Contraindications

Neomycin, Bacitracin, and Polymyxin” ointment should not be used in individuals who have shown sensitivity to any of the components. A possibility of increased absorption exists in very young children, thus Nebanol Plus® Ointment is not recommended for use in neonates.

Side Effects of Nebanol Plus 10 Ointment

• Common side impacts are Sickness; Spewing; Torment, burning, or swelling; Skin rashes; Conceivable kidney issues;
• Hearing misfortune; Tipsiness; Abnormal deadness of the skin; Muscle jerking; Seizures; Torment; Redness; Swelling at the infusion location.

Pregnancy & Lactation

There is little information to demonstrate the possible effect of topically applied neomycin in pregnancy and lactation. However, neomycin present in maternal blood can cross the placenta and may give rise to a theoretical risk of fetal toxicity, thus this ointment is not recommended in pregnancy and lactation.

Precautions & Warnings

It is to be noted that “Neomycin, Bacitracin, Polymyxin” Ointment is not intended for sterile use in surgical procedures such as those involving – abdominal or thoracic cavities there is evidence that neomycin, when in contact with peritoneal or pleural tissues, can potentiate neuromuscular block in patients under the influence of muscle relaxants, producing respiratory paralysis. As with other antibiotic preparations prolonged use may result in the overgrowth of non-susceptible organisms. Ototoxicity to neomycin has been reported. In neonates and infants, absorption by immature skin may be enhanced and renal function may be immature.

Storage Conditions

Store below 30° C, Protect from light.