Artesunate 50mg Tablet 6pcs

✔️ Uses of Artesunate 50mg Tablet

• Malaria

✔️ Side Effects of Artesunate 50mg Tablet

• Dizziness
• Diarrhea
• Belly pain
• Nausea

✔️ How does Artesunate 50mg Tablet work?

Artesunate 50mg Tablet helps in treating malaria where Artesunate works by transforming into a metabolite and binds with an iron component of blood and forms free radicals which inhibit the synthesis of protein and nucleic acid in Plasmodium parasites and prevent it from invading red blood cells, thus treating malaria effectively.

✔️ Quick Suggestions:

• Inform your doctor if you are allergic to Artesunate 50mg Tablet. Do not start or continue the treatment on your own.
• Consult your doctor if you are in the first 3 months of pregnancy or if you are breastfeeding.
• Avoid driving or operating machines after taking it because you may feel sleepy.
• Inform your doctor if you notice flu-like symptoms such as chills, fever, muscle pains, and any changes in the heartbeat.
• You may be asked for regular blood tests once a week while taking this medicine.

✔️ Indications:

• Treats severe malaria including cerebral malaria

✔️ Pharmacology

Artesunate, the active component, is metabolized to the active DHA. It generates free radicals inhibiting protein and nucleic acid synthesis in Plasmodium parasites during all erythrocytic stages. It may also lead to alkylation of parasitic proteins.

✔️ Dosage & Administration:

Artesunate 50 mg tablet:

• Adults: Two tablets twice on the first day, followed by one tablet twice daily for the next four days (4, 2, 2, 2, 2).
• Children:
  • 1-3 years: 3 tablets for 5 days (1, 1⁄2, 1⁄2, 1⁄2, 1⁄2)
  • 4-5 years: 6 tablets for 5 days (2, 1, 1, 1, 1)
  • 6-12 years: 8 tablets for 5 days (3, 2, 1, 1, 1)

Artesunate 100 mg tablet:

• Adults: One tablet twice on the first day, followed by half a tablet twice daily for the next four days (2, 1, 1, 1, 1).
• Children:
  • 4-5 years: 3 tablets for 5 days (1, 1⁄2, 1⁄2, 1⁄2, 1⁄2)
  • 6-12 years: 4 tablets for 5 days (1 1⁄2, 1, 1⁄2, 1⁄2, 1⁄2)
  • Patients aged over 12 years: Same as adult dose.

✔️ Interaction

• Interaction with other artemisinin drugs (e.g., artemether, arteether) prolongs PQ and QT interval.
• Interaction with antimalarial drugs (e.g., quinine, quinidine, mefloquine, halofantrine) with cardiac action.
• Interaction with drugs prolonging QT interval (e.g., erythromycin, terfenadine, astemizole, probucol, procainamide, disopyramide, amiodarone, bretylium, bepridil, sotalol, tricyclic antidepressants, and neuroleptics).

✔️ Contraindications

Artesunate is contraindicated in patients with known hypersensitivity to Artemisinin and its derivatives or inactive ingredients.

✔️ Pregnancy & Lactation

Considered safe for treating malaria in pregnancy, but further study is needed. Use with caution during breastfeeding, and it's recommended to stop breastfeeding during treatment.

✔️ Precautions & Warnings

• Caution in severe vomiting patients.
• Intravenous or intramuscular injection is preferred for emergency severe malaria treatment.
• Use under the advice of a Registered Physician.
• Do not exceed the recommended dose.

✔️ Storage Conditions

Keep below 30°C, away from light and moisture. Keep out of reach of children.