Ramicard 5mg Tablet 14pcs

Uses of Ramicard 5

• Hypertension
• Prevention of heart attack and stroke
• Heart failure

How does Ramicard 5 work?

Ramicard 5 inhibits ACE, reducing angiotensin II levels, promoting vasodilation, and decreasing aldosterone secretion, resulting in hypotensive effects.

Side Effects of Ramicard 5

Commonly reported side effects include dizziness, headache, fatigue, and asthenia. Less frequent side effects include symptomatic hypotension, cough, nausea, vomiting, rash, urticaria, anxiety, and amnesia. Rarely, angioneurotic edema, anaphylactic reactions, and hyperkalemia may occur.

Quick Suggestions:

• Rise slowly to avoid dizziness, especially during initial use.
• Report persistent cough or throat irritation.
• Avoid potassium supplements and potassium-rich foods.
• Inform your doctor if pregnant, planning pregnancy, or breastfeeding.

Indication of Ramicard 5

Ramicard 5 is indicated for congestive heart failure, myocardial infarction, hypertension, and stroke prevention.

Pharmacology

Ramicard 5 mg inhibits ACE, reducing the conversion of angiotensin I to angiotensin II, a vasoconstrictor. This leads to decreased vasopressor activity and aldosterone secretion, resulting in antihypertensive effects. It's also effective in managing heart failure and reducing the risk of cardiovascular events.

Dosage & Administration of Ramicard 5

Dosage should be adjusted based on patient response and tolerance.

• Hypertension: Initial dose of 1.25-2.5 mg once daily, maintenance dose of 2.5-20 mg daily.
• Congestive heart failure after myocardial infarction: Initiate therapy as early as 2 days post-myocardial infarction with 2.5 mg twice daily, titrated to 5 mg twice daily.
• Prevention of major cardiovascular events: Start with 2.5 mg once daily for the first week, then 5 mg once daily for 3 weeks; the maintenance dose may increase to 10 mg once daily.

Overdose may cause excessive peripheral vasodilation, bradycardia, electrolyte disturbances, and renal failure. Management includes gastric lavage, adsorbents, and supportive care.

• Dosage adjustments are needed for renal impairment.
• No information is available for pediatric use.
• Consider reduced initial doses for the elderly and those with hepatic impairment.

Swallow tablets with liquid; do not chew or crush. Absorption is unaffected by food.

Interaction

Concurrent use of diuretics can cause severe hypotension and hyperkalemia. Interaction with lithium can increase serum lithium levels. NSAIDs may reduce antihypertensive effects and worsen renal function.

Contraindications

• Hypersensitivity to Ramicard 5 mg or any ACE inhibitor
• History of angioedema
• Concomitant use with sacubitril/valsartan, aliskiren-containing medicines, or angiotensin II receptor antagonists in certain cases
• Pregnancy
• Avoid ACE inhibitors with certain extracorporeal treatments

Pregnancy & Lactation

Avoid during pregnancy. Discontinue if pregnancy is detected. Not recommended during lactation.

Precautions & Warnings

Use caution in patients with impaired renal function, hyperkalemia, hypotension, or impaired hepatic function.

Storage Conditions

Store below 30°C, protect from light, and keep out of reach of children. Do not use beyond the expiry date.