Trevox 750mg Tablet

Uses of Trevox 750mg Tablet

• Treats Bacterial Infections

How does Trevox 750mg Tablet work?

It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.

Side Effects of Trevox 750mg Tablet

Levofloxacin is generally well-tolerated, but some people may experience side effects, including dizziness, headache, nausea, constipation, and diarrhea.

Quick Suggestions:

• Your doctor has prescribed Trevox 750 to cure your infection and improve symptoms.
• Do not skip any doses and finish the full course of treatment even if you feel better.
• Discontinue Trevox 750 and inform your doctor immediately if you get a rash, itchy skin, swelling of your face and mouth, or difficulty in breathing.
• Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
• Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
• Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Indications:

Trevox 750 is an antibiotic used to treat various bacterial infections, including those affecting the lungs, sinuses, throat, skin, and soft tissues. It functions by inhibiting the growth of the bacteria responsible for the infection. The dosage and duration of treatment with Trevox 750 should be strictly adhered to as prescribed by your healthcare provider.

Pharmacology

Trevox 750 contains levofloxacin, a synthetic, broad-spectrum fluoroquinolone antibiotic. Levofloxacin works by inhibiting enzymes in bacteria, specifically topoisomerase IV and DNA gyrase, which are essential for processes like DNA replication, transcription, repair, and recombination. This action helps prevent the bacteria from multiplying and causing infection.

Dosage & Administration of Trevox 750mg Tablet

• Acute sinusitis: 500 mg or 750 mg once daily for 10-14 days.
• Chronic bronchitis flare-up: 500 mg once daily for seven days (uncomplicated) or 750 mg once daily for three days (complicated).
• Community-acquired pneumonia: 500 mg once daily for 7-14 days, or 750 mg once daily for five days.
• Uncomplicated urinary tract infections: 250 mg once daily for three days.
• Acute pyelonephritis and complicated urinary tract infections: 250 mg once daily for 7-10 days.
• Simple skin and soft tissue infections: 500 mg once daily for 7-10 days.
• Complicated skin and soft tissue infections: 750 mg once daily for 7-14 days.
• Enteric fever: 500 mg once daily for 7-14 days.
• Cholera, shigellosis, enteritis, and diarrhea: 500 mg for a mild to moderate case (single dose) or 500 mg once daily for three days in cases of moderate to severe pain.

Interaction

• Avoid administering any quinolone through the same intravenous line with solutions containing multivalent cations, like magnesium.
• Levofloxacin absorption can be affected by iron, antacids, and adsorbents.
• Nonsteroidal anti-inflammatory drugs (NSAIDs) may increase the likelihood of CNS stimulation.
• Levofloxacin might enhance the risk of bleeding when used with warfarin.

Contraindications

If you have a history of hypersensitivity to levofloxacin, quinolone antimicrobial agents, or any other component of the product, you should not take it.

Pregnancy & Lactation

Levofloxacin is not recommended for use during pregnancy or nursing due to its unknown effects on the unborn child or nursing infant.

Precautions & Warnings

• Levofloxacin injections should be administered slowly via intravenous infusion over 60 or 90 minutes, depending on the dosage.
• Adequate water intake is advised to prevent concentrated urine while taking Levofloxacin.
• Dosage adjustments should be made as needed during the administration of Levofloxacin.

Storage Conditions

Store Trevox 750 in a cool, dry place below 30°C, protecting it from light and moisture. Keep it out of the reach of children.