Oxigel 2.5% Topical Gel

Uses of Oxigel 2.5% Topical Gel

• Acne

How does Oxigel 2.5% Topical Gel work?

Oxigel 2.5% Topical Gel operates against acne-causing bacteria through a multi-step process:

Absorption and Conversion:

• After application on the affected skin, the gel is absorbed.
• It undergoes a conversion process, transforming into benzoic acid.

Metabolism and Release of Oxygen:

• Benzoic acid is metabolized by skin proteins.
• This metabolic process releases active free-radical oxygen species.

Alteration of Bacterial Proteins:

• The released oxygen species act on bacterial proteins, inducing alterations.

Treatment of Acne or Pimples:

• The altered bacterial proteins contribute to the treatment of acne or pimples.

Keratolytic Action:

• Oxigel 2.5% Topical Gel acts as a keratolytic agent.
• This promotes the peeling of the skin.

Oil Absorption:

• The gel absorbs excess oil from the skin.
• This helps prevent acne formation and skin irritation.

Side Effects of Oxigel 2.5% Topical Gel

Dry Skin:

• Skin may become dry as a result of using the gel.

Skin Redness:

• Redness of the skin can occur.

Peeling of the Skin:

• The outer layer of the skin may peel.

Burning Sensation of the Skin:

• Some individuals may feel a burning sensation on the skin.

Itching of the Skin (Pruritus):

• Itching or a sensation of skin irritation may occur.

Pain of the Skin (Pain, Stinging):

• Pain or stinging sensation on the skin can be experienced.

Skin Irritation:

• Skin irritation is a common side effect.

Allergic Contact Dermatitis:

• Allergic reactions leading to contact dermatitis may occur.

Quick Suggestions:

• Refrain from using harsh skincare products that may irritate your skin.
• Do not share cosmetic products, face towels, or bathing bars to prevent the spread of bacteria.
• Manage stress through relaxation techniques.
• Eat a healthy and balanced diet.
• Stay well-hydrated by drinking plenty of water.
• Incorporate regular exercise into your routine.
• Ensure you get enough sleep.
• Rinse your face with water several times a day to prevent breakouts.
• Refrain from scratching or picking your skin to prevent infections in the affected areas.
• Stay hydrated by drinking 3-4 liters of water daily to help eliminate toxins from the body.
• Include anti-inflammatory foods in your diet, such as fruits, vegetables, and omega-3 fatty acids.
• If you do not notice improvement after 4-6 weeks of using Benzac Ac 5% Gel Wash, consult your dermatologist for further evaluation.
• If acne persists, consider ultrasound scanning of the abdomen to check for the possibility of Polycystic Ovarian Disease (PCOD).

Indications

Oxigel 2.5% Topical Gel is used in the treatment and prevention of acne (pimples) in the face, chest, and back. It can also be used to unplug the blocked pores (blackheads and whiteheads) and absorb excess oil from the skin. Consult your doctor before using Oxigel 2.5% Topical Gel.

Pharmacology

The action of benzoyl peroxide is attributed to its ability to produce free-radical oxygen, resulting in several beneficial effects:

• Benzoyl peroxide produces free-radical oxygen.
• The free-radical oxygen oxidizes bacterial proteins.
• Benzoyl peroxide exhibits moderate keratolytic action.
• Keratolytic agents promote the shedding or peeling of the outer layer of the skin.
• The oxidizing action on bacterial proteins contributes to its antibacterial effect.
• It works against specific bacteria, including Propionibacterium acnes and Staphylococcus epidermidis.
• Propionibacterium acnes and Staphylococcus epidermidis are bacteria commonly associated with skin issues, including acne.

Dosage & Administration:

• Always apply Oxigel 2.5% Topical GelL as directed by your physician.
• External use only.
• Apply a thin layer on the affected area as instructed by the doctor.
• Avoid contact with eyes, lips, mouth, nose, mucous membranes, and sensitive areas of the neck.

Dosage Instructions:

• Your doctor will determine the correct dose and duration based on your age, body weight, and the severity of the disease condition.

Interaction

Drug-Drug Interactions:

Before using Oxigel 2.5% Topical Gel, it is crucial to inform your doctor if you are taking or using any of the following medications:

Medicines for Skin Diseases (e.g., dapsone):

• Interaction with other medications used to treat various skin diseases.

Topical Hydroquinone:

• Interaction with medications containing hydroquinone, which is used to remove dark patches of the skin.

Isotretinoin, Topical Tretinoin:

• Interaction with isotretinoin and topical tretinoin, commonly used to treat acne.

Topical Anaesthetics (e.g., benzocaine, lignocaine):

• Interaction with topical anesthetics used for pain and itching relief.

Drug-Food Interactions:

Before using Oxigel 2.5% Topical Gel, inform your doctor if you have any allergies to other medicines, foods, preservatives, or dyes.

Contraindications

Hypersensitivity

Pregnancy & Lactation

Pregnancy Classification C. Either animal research has indicated negative effects on the fetus (teratogenic, embryocidal, or other) but no controlled studies in women exist, or studies in women and animals are unavailable. Only if the possible benefit outweighs the danger to the fetus should drugs be administered.

Precautions & Warnings

Application Area:

• Use Benzoyl Peroxide only on your skin.

Avoid Specific Areas:

• Keep it away from sensitive areas such as eyes, eyelids, lips, mouth, and inside the nose.

Immediate Rinse:

• If the medicine comes in contact with any sensitive areas, wash the affected area with water immediately.

Avoid Scratched or Eroded Skin:

• Do not use Benzoyl Peroxide on scratched or eroded skin and open wounds.

Caution with Sensitive Areas:

• Take care when applying Benzoyl Peroxide on sensitive areas of the skin, such as the neck.

Sun Sensitivity:

• Benzoyl Peroxide can increase skin sensitivity to sunlight.

Sun Protection:

• Avoid sunbeds/lamps and minimize sun exposure. Use sunscreen and wear protective clothing while using Benzoyl Peroxide.

Bleaching Properties:

• Avoid contact with hair, as Benzoyl Peroxide has bleaching properties.

Bleaching of Fabrics:

• Be cautious about contact with dyed or colored fabric, furniture, or carpeting, as Benzoyl Peroxide can bleach these materials.

Storage Conditions

• Keep out of sight and reach of children
• Store at room temperature