Ebatin Syrup

Uses of Ebatin Syrup

• Treats seasonal and perennial allergic rhinitis
• Treats chronic idiopathic urticaria

How Ebatin Syrup works?

Ebatin Syrup works by inhibiting the activity of histamine (a chemical messenger responsible for allergic reactions in the body), resulting in relief from allergy symptoms such as swelling, itching, runny nose, sneezing, rashes, and watery eyes.

Side effects of Ebatin Syrup

• Headache
• Dry mouth
• Drowsiness
• Abdominal pain
• Nausea
• Indigestion
• Weakness
• Irregular heartbeat
• Pharyngitis (sore throat)
• Asthenia (weakness)
• Epistaxis (nosebleed)
• Rhinitis, sinusitis (infection or inflammation of nose and sinuses)

Quick Suggestions:

• The doctor has prescribed Ebatin to help relieve allergy symptoms such as itching, swelling, and rashes.
• As compared to other similar medications, it is much less likely to make you feel sleepy.
• Be cautious while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
• Do not drink alcohol while taking this medication as it may cause increased sleepiness.
• Include citrus fruits in your diet as they help in reducing allergies.
• Exercise regularly and include healthy food to keep your immune system at bay.
• Avoid getting in contact with allergens (allergy-causing agents) such as dust, pollen, mold, insects, etc.
• Stop taking Ebatin at least three days before taking an allergy test as it can affect the test results.

Indication of Ebatin Syrup

Ebatin Syrup is an effective anti-allergic medicine used to relieve the symptoms caused by allergic reactions such as hay fever or urticaria (hives). These symptoms may include a runny nose, watery eyes, itchy eyes, redness of the eyes, sneezing, itching, skin rashes, etc.

Pharmacology

Ebastine is a long-acting and selective antagonist of the H1-histamine receptor. The blockage of peripheral receptors stays stable after repeated treatment. Following oral administration, ebastine is readily absorbed and undergoes significant first-pass metabolism. Carebastine, a pharmacologically active acid metabolite, is almost completely transformed from ebastine.

Dosage & Administration of Ebatin Syrup

It is important to note that dosages can vary based on a person's age, weight, medical condition, and other factors. Therefore, it is always best to follow the dosing instructions provided by a healthcare professional.

Based on the information you provided, here are some key takeaways regarding the dosing of ebastine:

• For children aged 2-5 years, the recommended dose is 2.5 ml once daily. The dose can be increased to up to 5 ml in severe cases such as Perennial Allergic Rhinitis.
• For children aged 6-12 years, the recommended dose is 5 ml once daily. The dose can be increased to up to 10 ml in severe cases such as Perennial Allergic Rhinitis.
• Ebastine may be taken with or without food.

Take Ebatin Syrup as advised by your physician. Shake well before use. It can be taken with or without food. Your doctor will decide the correct dose and duration for you depending on your age, body weight, and disease condition.

Interaction

Ketoconazole, itraconazole, clarithromycin, and erythromycin are examples of medications that can inhibit the metabolism of ebastine in the body. This inhibition can lead to higher plasma levels of ebastine, which may increase the risk of QTc interval prolongation, a type of heart rhythm disturbance that can be serious. It is important to talk to your healthcare provider before taking ebastine with any other medications, including over-the-counter drugs and herbal supplements, to avoid any potential drug interactions.

Contraindications

Patients who have previously tested positive for Ebastine or any of its components.

Pregnancy & Lactation

According to the USFDA's pregnancy categorization rules, ebastine falls under pregnancy category B. Studies in rats and rabbits show no direct or indirect adverse effects on the embryo or fetal development or the course of gestation and peri- and post-natal development. There have been no reports of teratogenic consequences in animals. However, no well-controlled studies in pregnant women have been conducted, and reproductive studies are not always predictive of human response. As a result, ebastine should only be administered during pregnancy if absolutely necessary. Because it is unknown whether ebastine is excreted in human milk, it should not be used during lactation.

Precautions & Warnings

• Do not take Ebatin Syrup if you are allergic to any of its contents.
• If you have heart disease such as ECG alteration (prolongation of QT interval), talk to your doctor before taking Ebatin Syrup.
• If you have low levels of potassium in the blood, take Ebatin Syrup with caution.
• Avoid consuming Ebatin Syrup along with erythromycin (antibiotics) and ketoconazole (anti-fungal) as it might lead to higher levels of Ebatin Syrup in the blood leading to toxicity.
• If you are pregnant or breastfeeding, consult your doctor before taking Ebatin Syrup.
• Ebatin Syrup may cause drowsiness and dizziness, so do not drive if you are not alert.
• Ebatin Syrup is not recommended for children as safety has not been established.
• Avoid consuming alcohol along with Ebatin Syrup as it could lead to increased drowsiness and dizziness.

Storage Conditions

Store below 30°C, away from light, in a cool, dry location. Keep out of children's reach.