Apidra Solostar 100IU/ml Injection

Uses of Apidra Solostar 100IU/ml Injection 3 ml

• Diabetes (Type-1 Diabetes Mellitus, Type-2 Diabetes Mellitus)

How Apidra Solostar Pen works

Apidra Solostar 100IU/ml Injection is a fast-acting insulin that starts working within 10-20 minutes after injecting. It works similarly to the insulin produced by the body. Insulin facilitates the reuptake of glucose in muscle and fat cells and also blocks the release of glucose from the liver.

Side Effects for Apidra Solostar Pen

• Decreased blood Glucose Levels
• Headache
• Fast heartbeat
• Blurred vision
• Dizziness
• Sore throat
• Responses at the injection location (such as reddening, unusually intense pain on injection, itching, hives, swelling, or inflammation)
• Hypoglycaemia (low blood sugar level)
• Hypokalaemia (low potassium)
• Lipodystrophy (fat deposition under the skin)
• Rash
• Upper respiratory tract infection
• Pruritus (itchy skin)
• Unusual tiredness and weakness

Quick Suggestions:

• Take it 15 minutes before a meal or within 20 minutes after starting a meal.
• To avoid firm lumps forming at one injection site, injection sites must be changed.
• Injections beneath the skin of the belly result in quicker absorption than injections at other locations.
  If the mixture is no longer clear and colorless, or if particulates are present, do not use it.
• Hypoglycemia is a frequent complication. Check your blood sugar levels on a frequent basis.
• Always keep some sugary food or fruit drink on hand in case of hypoglycemia signs like chilly chills, cool pallid skin, tremors, fatigue, and anxiety.
• Exercise can reduce your body's need for insulin both during and after physical exercise.
• Exercise may also hasten the impact of an insulin dosage, particularly if it includes the injection site. (for example, the leg should not be used for injection just prior to running).
• Consult your doctor about how to modify your insulin plan to suit exercise.
• Avoid sugary foods and opt for low-calorie prepared foods.
• Unopened vials/cartridges can be stored at room temperature for up to 4 weeks, whereas opened vials must be kept in the refrigerator (2°C-8°C).

Indications of Apidra Solostar 100IU/ml

100 IU/ml Apidra Solostar Injection For the management of diabetes mellitus in both adults and children (over the age of six), 3 ccs of rapid-acting insulin is used. Insulin glulisine is the main component of Apidra Solostar 100IU/ml Injection 3 milliliter. 100 IU/ml Apidra Solostar Injection An equivalent to normal human insulin, 3 ml is a synthetic human insulin derivative. Compared to normal human insulin, insulin glulisine has a quicker start effect and a shorter half-life. A person's blood sugar level will consistently be too high if they have diabetes, which is a permanent disease.

Fast-acting insulin Apidra Solostar 100IU/ml Injection 3 milliliter quickly normalizes blood sugar levels after a meal. After infusion, it usually starts to work within 10–20 minutes, surges after an hour, and continues to work for another 2–4 hours. Apidra Solostar 100IU/ml Injection 3 ml should typically be given in conjunction with intermediate-acting or long-acting insulin preparations due to its brief effect. The action of Apidra Solostar 100IU/ml Injection 3 ml is to ensure quick and reliable sugar management. Fast-acting insulin, such as Apidra Solostar 100IU/ml Injection 3 ml, aids in lowering blood sugar levels following a meal. reduces the chance of developing serious consequences from diabetes.

Controlling glucose metabolism is the main function of insulin and its derivatives, including insulin glulisine. By promoting peripheral glucose uptake, especially in skeletal muscle and fat, and preventing hepatic glucose synthesis, insulin reduces blood glucose levels. Insulin glulisine starts working about two times as quickly as normal human insulin and finishes reducing blood sugar about two hours sooner.

You'll receive instructions from your doctor on how to use 3 milliliters of Apidra Solostar 100IU/ml Injection. It needs to be given between 0 and 15 minutes before or right after meals.

Pharmacology

Insulins and insulin analogs, especially insulin glulisine, have the primary role of regulating glucose metabolism. Insulin reduces blood glucose levels by boosting skeletal muscle and adipose glucose uptake while inhibiting hepatic glucose synthesis. Insulin increases protein production while decreasing lipolysis and proteolysis. Insulin Glulisine and regular human insulin have the same glucose-lowering benefits when administered intravenously. After subcutaneous injection, insulin glulisine has a quicker start and a shorter period of an effect than regular human insulin.

Dosage of Apidra Solostar 100IU/ml

When administered intravenously, Insulin Glulisine is a recombinant insulin analog that is equipotent to human insulin (i.e., one unit of Insulin Glulisine has the same glucose-reducing impact as one unit of normal human insulin). Insulin Glulisine has a faster start of the action and a shorter duration of action than normal human insulin when administered subcutaneously.

Insulin Glulisine dose must be tailored to the person. Blood glucose monitoring is important in all insulin-treated individuals. The overall daily insulin needs vary, but it is typically between 0.5 and 1 Unit/kg/day. Insulin requirements can vary as a result of stress, severe sickness, or changes in activity, meal habits, or medications.

Administrations of Apidra Solostar 100IU/ml

• Apidra Solostar Injection 100 IU/ml 3ml is injected into the belly or leg at least 15 minutes before a meal or 20 minutes after it has begun.
• Additionally, it can be infused with 0.9% sodium chloride intravenously (IV).
• However, compared to other injection locations, subcutaneous administration of Apidra Solostar 100IU/ml Injection 3 ml in the abdominal area guarantees quicker absorption.
• When both a fast and extended insulin response is sought, a dose of 3 ml of Apidra Solostar 100IU/ml Injection is typically administered once or twice daily.
• The dosage necessary for the initial needs is typically between 0.3 and 1.0 IU/kg per day.
• A dinner or refreshment containing sugar or glucose should be consumed within 30 minutes of administering Apidra Solostar 100IU/ml Injection 3 milliliter. (carbohydrates).
• Ask a medical expert to give Apidra Solostar 100IU/ml Injection 3 ml if you are not adequately educated to do so.

Directions for use Apidra Solostar 100IU/ml

When self-injecting insulin, follow these steps: 

• Wash your hands before you administer insulin
• Roll the insulin bottle; and
• clean the bottle top.
• Pull the syringe's handle down to the correct dosage that your doctor has recommended.
• Push the hypodermic plunger down after inserting the needle into the container.
• Reset the piston to the specified number of units by pulling it down once more.
• Grab an alcohol brush and clean the injection location.
• Pinch up the epidermis and then insert the plunger after the needle has been inserted.
• To ensure that the full dosage is injected, the needle needs to remain subcutaneous for at least 6 seconds.
• Pull out the cannula after administering the insulin, then properly discard the syringe.
• After that, you can eat or have a refreshment.

Interaction

• Apidra Solostar 100IU/ml Injection 3 ml may interact with medicines that could raise the risk of antiarrhythmic (disopyramide), hemorheological agents (pentoxifylline), antidiabetic medications (pramlintide, glucagon), beta-blockers (metoprolol), diuretics (furosemide), bleeding disorder medications (octreotide), antipsychotic (propoxyphene, pheno (isoniazid).
• Ayurvedic, homeopathic, Unani, herbal remedies, or over-the-counter medicines may combine with Apidra Solostar 100IU/ml Injection 3 ml. If you use these items, tell your doctor. Alcohol consumption should be avoided while taking Apidra Solostar 100IU/ml Injection 3 ml as it may raise or lower your blood sugar levels.
• Patients with renal disease, liver disease, low blood sugar/glucose levels (hypoglycemia), and low potassium levels shouldn't receive Apidra Solostar 100IU/ml Injection 3 ml. (hypokalaemia).

Contraindications

People who have hypoglycemia or who are allergic to Insulin Glulisine or any of its excipients shouldn't use the medication.

When taking this medicine, patients who have a history of hypersensitivity to Insulin Glulisine or its excipients may suffer localized or generalized hypersensitivity reactions.

Pregnancy & Lactation

Pregnancy Classification C. Although animal reproduction studies have indicated that the medication harms the fetus, and there are no appropriate and well-controlled human trials, the drug's potential advantages may justify its usage in pregnant women despite the dangers.

It is uncertain if insulin glulisine is excreted in human milk by nursing mothers. Because many medications are excreted in human milk, Insulin Glulisine should be given with caution to a breastfeeding mother. Insulin Glulisine can be used during breastfeeding, although diabetic women who are nursing may need to modify their insulin dosage.

Precautions & Warnings

• When pioglitazone was combined with insulin, particularly in individuals who were at high risk for cardiac heart failure, cases of heart failure were observed.
• The initial signs of hyperglycemia (high blood sugar level) may include symptoms such as excessive thirst, parched lips, more frequent urination, nausea, vomiting, drowsiness, flushed dry skin, lack of hunger, and breath odor that smells strongly of acetone. You ought to keep a careful eye on these signs.
• Before using Apidra Solostar 100IU/ml Injection 3 ml, inform your doctor if you have ever experienced a heart attack, have gained weight, or have edema (fluid accumulation in tissue).
• It is best to avoid drinking because it has the potential to either raise or lower your blood glucose level. When traveling across more than two time zones, caution should be exercised.
• Your specialist might change your insulin regimen. If the potassium level is too low (hypokalemia), Apidra Solostar 100IU/ml Injection 3 ml may cause breathing paralysis, abnormal heartbeat rate, unconsciousness, and even mortality.
• If you have any kidney, liver, heart, or issues with alcohol or other prescribed recreational drugs, you should not take Apidra Solostar 100IU/ml Injection 3 ml.

Storage Conditions

Vials and cartridge devices for insulin glulisine should be stored between 2 and 8 degrees Celsius in the refrigerator. Don't expose yourself to the heat. Never store or allow Insulin Glulisine to solidify in a fridge. Throw it out if it has been chilled. Unopened vials/cartridge devices must be used within 28 days if not stored in the refrigerator.

Any unsealed vials, whether chilled or not, must be used within 28 days of opening. The open vial in use can be kept in storage without direct heat or light for up to 28 days if cooling is not feasible, provided that the temperature does not rise above 25°C.