Adafil 20mg Tablet

Uses of Adafil 20mg Tablet

• Erectile dysfunction (Impotence)
• Benign prostatic hyperplasia (BPH), 
• Pulmonary arterial hypertension (PAH)

How does Adafil 20mg Tablet work?

Adafil 20mg Tablet functions as a phosphodiesterase (PDE-5) inhibitor. Its mechanism involves increasing blood circulation to the penis by relaxing the muscles in the blood vessels of the penile region, thus aiding in treating erectile dysfunction. Furthermore, Adafil 20mg Tablet relaxes and widens blood vessels within the lungs. This relaxation facilitates improved blood flow through the lungs, enabling the heart to pump blood more effectively and subsequently lowering blood pressure within the lungs.

Side Effects of Adafil 20mg Tablet

• Dizziness
• Headache
• Indigestion
• Back pain
• Nasal congestion

Quick Suggestions:

• Maintain a healthy weight, practice a balanced diet, and engage in regular exercise to manage erectile dysfunction. Foster intimacy with your partner.
• Stay sexually active to help prevent further erectile dysfunction issues.
• Avoid consuming foods like sugars, carbonated beverages, tea, citrus fruits, tomatoes, spicy foods, and chocolate.
• Manage fluid intake to avoid frequent urination urges.
• Limit alcohol and caffeinated drinks, as they can worsen symptoms.
• Ensure adequate fluid intake, aiming for 6-8 glasses daily.
• Opt for whole, unprocessed foods while avoiding processed options.
• Incorporate fruits, vegetables, and fiber-rich foods into your diet.
• Take Adafil 20mg Tablet 30 minutes to 4 hours before engaging in sexual intercourse, preferably an hour before.
• Do not exceed one dose of Adafil 20mg Tablet in a day; adhere to your doctor's prescription.
• If an erection persists for over four hours, consult your doctor promptly.

Indication

Adafil 20mg Tablet falls under the category of phosphodiesterase type 5 (PDE 5) inhibitors. It is utilized to address erectile dysfunction (impotence) and benign prostatic hyperplasia (BPH). On occasion, Adafil 20mg Tablet is also employed to manage pulmonary arterial hypertension (high blood pressure in the lungs).

The mode of action of Adafil 20mg Tablets involves relaxing the blood vessels in the penis. This relaxation facilitates blood flow into the penis during sexual arousal, thereby aiding in the treatment of erectile dysfunction. Additionally, Adafil 20mg Tablet relaxes muscles in the bladder and prostate, subsequently alleviating symptoms associated with an enlarged prostate, such as difficulty urinating and urgency.

For addressing pulmonary hypertension, Adafil 20mg Tablet functions by relaxing blood vessels within the chest. This results in an increased blood supply to the lungs and a reduced workload for the heart.

Pharmacology

Tadalafil acts as a precise inhibitor of phosphodiesterase type 5 (PDE5). The inhibition of PDE5 leads to elevated levels of cyclic guanosine monophosphate (cGMP) within smooth muscle cells. This increase in cGMP brings about two significant effects: relaxation of smooth muscles and augmented blood flow into the corpus cavernosum, which ultimately results in the attainment of a penile erection.

PDE5 isn't solely confined to the penile region; it's also present in the smooth muscles of the prostate and bladder walls. By inhibiting PDE5, the cGMP levels rise, inducing relaxation in these muscles within the prostate and bladder. This relaxation of smooth muscles may lead to improved blood flow to the urinary system and a broader opening of the bladder neck. This combined effect facilitates better voiding and urinary function.

Dosage & Administration of

Erectile Dysfunction:

• Typically, a starting dose of 10 mg is recommended for most patients.
• The dosage can be adjusted based on need, with the option to increase to 20 mg or decrease to 5 mg.
• The maximum frequency for dosing is once daily.
• Tadalafil remains effective for up to 36 hours.

Benign Prostatic Hyperplasia:

• The advised dosage is 5 mg, taken consistently at the same time each day.

Combined Erectile Dysfunction and Benign Prostatic Hyperplasia:

• The recommended dose is 5 mg, taken at the same time every day.

Missed Dose:

• Adafil 20mg Tablet is generally taken on an as-needed basis, reducing the likelihood of missing a dose. However, if you are following a scheduled dosing regimen and you miss a dose, take it as soon as you remember. If your next dose is approaching, skip the missed dose and proceed with your regular schedule. Avoid doubling your dose to compensate for the missed one.

Overdose:

• It is crucial to strictly adhere to the prescribed dose ofAdafil 20mg Tablet. In the event of accidentally consuming more than the prescribed amount, seek immediate medical attention. Overdosing can have serious consequences and should be addressed promptly.

Interaction

When multiple medications are taken together or combined with specific foods and beverages, the risk of drug interactions increases. Here are some considerations for Adafil 20mg Tablet:

Interaction with Alcohol: Taking this medicine along with alcohol may result in significantly reduced blood pressure, leading to potential fainting, sweating, and dizziness. Therefore, it is advised to limit alcohol consumption while using this medication.

Interaction with Other Medications: Adafil 20mg Tablet can interact adversely with certain medications, such as:

• Nitroglycerin
• Phenytoin
• Ketoconazole
• Amlodipine
• Carbamazepine
• Cimetidine

Interaction with Specific Diseases: Adafil 20mg Tablet can also interact unfavorably with certain medical conditions, including:

• Asthma
• Impaired kidney function
• Gastrointestinal toxicity

To ensure your safety and the effectiveness of the medication, it's important to inform your healthcare provider about all the medications you are taking, your medical history, and any existing health conditions. This will help them assess and manage potential interactions and choose the best treatment approach for you.

Contraindications

Nitrates (for example, Nitroglycerine and isosorbide) may augment the hypotensive effects of Nitrates. Tadalafil hypersensitivity reactions

Pregnancy & Lactation

Adafil 20mg Tablet is indicated only for men. Thus its use in pregnant women is insignificant.

Precautions & Warnings

It's crucial to avoid Adafil 20mg Tablets in various scenarios including angina (chest pain), renal impairment (kidney problems), hepatic impairment (liver problems), and instances involving bleeding when taking medications like Nitrates, Alpha Blockers, Alcohol, CYP3A4 Inhibitors (such as Ritonavir, Ketoconazole, and Itraconazole), or other PDE5 inhibitors. These precautions are essential to ensure your safety and prevent potential complications.

Storage Conditions

Keep away from light and heat in a dry location. Keep out of children's reach.