Actose 15mg Tablet

Uses of Actose 15mg Tablet

• Treatment of Type 2 Diabetes Mellitus

How does Actose 15mg Tablet work?

Actose 15mg Tablet efficiently manages blood sugar by containing pioglitazone, a PPAR-gamma and PPAR-alpha agonist. Upon administration, it activates specific receptors (PPAR-gamma and PPAR-alpha) that play a role in glucose metabolism. This encourages the body to use insulin for processing circulating glucose, lowering blood sugar levels. Moreover, the tablet can decrease glucose production by the liver.

Side Effects of Actose 15mg Tablet

• Upper respiratory tract infection
• Headache
• Sinusitis
• Myalgia (muscle pain)
• Pharyngitis (inflammation of pharynx located back of neck)

Quick Suggestions:

• Actose 15mg Tablet helps to control blood sugar levels and avoid long-term complications.
• Take it only as per the dose and duration suggested by your doctor.
• You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with the Actose 15mg Tablet.
• Full effects may be visible after several weeks of starting Actose 15mg Tablet. Keep taking it as prescribed by your doctor.
• Monitor your blood sugar level regularly while taking this medicine.
• Notify your doctor if you experience shortness of breath, heart problems, or any abnormal swelling.
• Your doctor may monitor your liver function. Inform your doctor if you notice symptoms like abdominal pain, yellowing of eyes, and loss of appetite.

Indication

• Type II Diabetes Mellitus involves ineffective insulin use, leading to high blood sugar levels.
• Insulin helps move sugar from the blood to cells.
• With Type II diabetes, insulin isn't utilized properly, causing elevated blood sugar.
• Actose 15mg Tablet manages high blood sugar levels in Type II diabetes.

Pharmacology

Keep taking this medicine, even if you feel well or your blood sugar levels are controlled. If you stop it without consulting your doctor, your blood sugar levels could rise and put you at risk of kidney damage, blindness, nerve problems, and loss of limbs. Remember that it is only part of a treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. Your lifestyle plays a big part in controlling diabetes.

Dosage & Administration of

For adults with Type 2 diabetes mellitus:

• Take 15 mg of Actose 15mg Tablet orally once daily.

For the elderly:

• No dosage adjustment is needed.

For those with renal impairment:

• No dosage adjustment is required.

For hepatic impairment (moderate to severe):

• Avoid using the medication.

To consume Actose 15mg Tablet:

• Follow your physician's advice.
• Swallow the tablet with water.
• Do not crush or chew it.
• Your doctor will determine the suitable dose and duration based on your age, weight, and health condition.

Interaction

Drug-Drug Interactions:

• Actose 15mg Tablet might interact with antidiabetics (like gemfibrozil) and antibiotics (such as rifampicin).
• Inform your doctor about using these medications before taking Actose 15mg Tablet 10's.

Drug-Food Interactions:

• Combining Actose 15mg Tablet 10's with alcoholic beverages could heighten the risk of lactic acidosis (excessive lactic acid buildup) and hypoglycemia, a rare but severe condition.

Drug-Disease Interactions:

• Avoid Actose 15mg Tablet 10's if you have congestive heart failure, type I diabetes, bladder cancer, edema, liver disease, macular edema, premenopausal anovulation, obesity, or anemia, as it may worsen these conditions.

Contraindications

Do not take Actose 15mg Tablet if:

• You're allergic to Pioglitazone or any of its ingredients.
• You have diabetic ketoacidosis (uncontrolled diabetes with symptoms like nausea, vomiting, diarrhea, and rapid weight loss).
• You have heart problems, especially heart failure.
• You experience liver issues.
• You've had or currently have bladder cancer.
• You observe blood in your urine without your doctor's knowledge.

Pregnancy & Lactation

Pregnancy: There are no appropriate and well-controlled studies on pregnant women. Pioglitazone should only be used during pregnancy if potential profit justifies the potential risk for the fetus.

Lactation: We do not know if pioglitazone is secreted in human milk. As many drugs are excreted in breast milk, they should not be administered to lactating women.

Precautions & Warnings

Fluid Retention and Heart Failure:

• Fluid retention (edema) can occur, potentially leading to congestive heart failure. Combining Actose 15mg Tablet 10's with insulin or using it in heart failure patients can increase risks.

Kidney Disease:

• If you have kidney disease, as indicated by blood tests, avoid Actose 15mg Tablet 10's.

Blood Sugar Levels and Insulin:

• Actose 15mg Tablet, with or without insulin, tends to lower blood sugar levels. Your doctor may adjust the insulin dose accordingly.

Fracture Risk:

• Some women taking Actose 15mg Tablet might face an increased fracture risk.

Bladder Cancer and Macular Edema:

• Consult your doctor before using Actose 15mg Tablet if you have bladder cancer or macular edema (retinal fluid build-up in the eye's macula).

Storage Conditions

Protect from light and moisture by storing below 30°C. Keep the medicine out of children's reach.