Acmegra 100mg Tablet | Sildenafil | Price | Substitutes | ePharma
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Acmegra 100mg Tablet

Generic: Sildenafil

Type: Tablet

Pack Size: 4s pack

Not Available

Sildenafil is indicated for the treatment of erectile dysfunction.


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Discount Price: ৳ 186.93
MRP: ৳ 201 7% Off

⪼ Save  ৳: 14.07  in this Product



Description:

Acmegra 100mg Tablet belongs to the phosphodiesterase type-5 (PDE 5) inhibitors group and is mainly used to treat adult men with erectile dysfunction (impotence). It can also be prescribed to treat pulmonary arterial hypertension, improving exercise capacity and slowing down clinical worsening.

By relaxing the blood vessels in the penis, Acmegra 100mg Tablet facilitates blood flow during sexual excitement, effectively treating erectile dysfunction. Furthermore, it dilates blood vessels, augmenting blood supply to the lungs, and eases the heart's workload, thereby addressing pulmonary hypertension.

Take Acmegra 100mg Tablet as prescribed by your doctor, considering your medical condition. Possible side effects like headache, nausea, dizziness, indigestion, and stomach upset may occur but often resolve gradually without medical intervention.

Avoid Acmegra 100mg Tablet if you're allergic to its components, nitrates, or riociguat. It's not recommended for children. Consult your doctor if you experience hearing or visual impairment. Refrain from alcohol consumption as it can hinder erection. If taken after a heavy meal, the medicine may take longer to work, so lighter meals are advised.

Safety Advices


Alcohol
UNSAFE

Drinking alcohol is known to cause erection impairment. You are advised not to drink alcohol in extreme amounts before taking Sildenafil.


Pregnancy
UNSAFE

Sildenafil is a medicine used to treat erectile dysfunction in males. Thus, it is not recommended to administer to pregnant women.


Breastfeeding
UNSAFE

Sildenafil is a medicine used to treat erectile dysfunction in males. Thus, it is not recommended to administer to pregnant women.


Driving
CAUTION

Sildenafil can cause dizziness and can affect your vision. You should be careful if you need to drive.


Kidney
CONSULT YOUR DOCTOR

Acmegra 100mg Tablet should be used with caution in patients with kidney diseases. Therefore, consult your doctor before taking it.


Liver
CONSULT YOUR DOCTOR

Acmegra 100mg Tablet is not recommended for use in patients having severe liver diseases. It should be used with caution in patients with other minor liver problems. Therefore, consult your doctor before taking it.

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Uses of Acmegra 100mg Tablet
  • Improves blood flow and oxygen supply to the penis
How does Acmegra 100mg Tablet work?

Acmegra 100mg Tablet works by blocking the effects of certain enzymes (PDE5) which limits blood flow to the penis. Therefore, it relaxes the blood vessels supplying the penis and improves blood flow and oxygen supply.

Side Effects of Acmegra 100mg Tablet
  • Headache
  • Nausea
  • Dizziness
  • Indigestion
  • Stomach upset
Quick Suggestions:
  • Take Acmegra 100mg Tablet an hour before intercourse, not exceeding one dose per day. 
  • Seek help if an erection lasts too long. 
  • Do not take it if you've used nitrates recently or had heart issues. 
  • Consult a doctor before using Sildenafil if you're pregnant, breastfeeding, or have certain medical conditions.
Indication
  • Erectile dysfunction, also known as impotence, erectile dysfunction is an inability to develop or maintain proper penile erection to perform sexual activity
  • Pulmonary arterial hypertension is a health complication marked by increased blood pressure in the arteries connected to the heart
Pharmacology

Sildenafil is a selective inhibitor of cyclic Guanosine Monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) used for the treatment of erectile dysfunction. It enhances the effect of nitric oxide (NO) by blocking phosphodiesterase type 5 (PDE5). PDE5 is responsible for the degradation of cGMP in the corpus cavernosum, leading to the relaxation of smooth muscles and increased blood flow to the corpus cavernosum. This mechanism contributes to the improvement of erectile function.

Dosage & Administration of

The recommended dosage of Sildenafil (such as in Acmegra 100mg Tablet) and instructions for its use are as follows:

  • The typical starting dose is 50 mg of Sildenafil, taken about 1 hour before engaging in sexual activity.
  • Sildenafil can be taken anywhere from 30 minutes to 4 hours before sexual activity, based on individual preferences and toleration.
  • Depending on its effectiveness and how well it's tolerated, the dose can be adjusted. It may be increased to a maximum of 100 mg or decreased to 25 mg.
  • The maximum frequency of dosing is once per day.

When taking Acmegra 100mg Tablet:

  • Follow your doctor's instructions regarding the dose and duration of use.
  • Swallow the tablet whole. Do not chew, crush, or break it.
  • Acmegra 100mg Tablet can be taken with or without food, but taking it at a consistent time is recommended.

In the case of overdose:

  • Overdosing on Sildenafil may lead to symptoms such as headache, flushing, dizziness, dyspepsia, nasal congestion, and altered vision.
  • If you suspect an overdose, seek emergency medical assistance immediately.

If you miss a dose:

  • If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.
Interaction

Sildenafil interacts with other medicines and certain food items in the following ways:

Medicine Interactions:

Nitrates: Concurrent use of Sildenafil and medicines containing nitrates can result in dangerous hypotensive effects, leading to a significant drop in blood pressure. This combination should be avoided.

Alpha-Blockers: Co-administration of Sildenafil with alpha-blockers can cause a reduction in blood pressure. Caution is advised when using these medications together.

Amlodipine: Interaction between Sildenafil and Amlodipine may result in an increase in blood pressure. Monitoring is recommended if these medications are used concurrently.

CYP3A4 Inhibitors (e.g., Ritonavir): Sildenafil's exposure may increase when co-administered with CYP3A4 inhibitors like Ritonavir, commonly used in HIV treatment. This could lead to higher levels of Sildenafil in the body.

Food Interactions: Sildenafil can have significant interactions with certain food items:

Grapefruit and its Juice: Consuming grapefruit or its juice in combination with Sildenafil can lead to potentially dangerous effects, as it may interfere with the metabolism of the medication in the body.

Pomelo and its Juice: Similar to grapefruit, consuming pomelo or its juice alongside Sildenafil can also lead to adverse effects due to potential interactions.

Contraindications

Sildenafil should not be used under the following circumstances:

Regular Smokers: Regular smokers are advised against using Sildenafil due to the risk of a severe eye side effect known as NAION (non-arteritic anterior ischemic optic neuropathy), which involves excessive blood loss in the optic nerve.

Cardiovascular Conditions: Individuals who have experienced heart attacks, low blood pressure, myocardial infarction (heart attack), stroke, and cardiac failure are also cautioned against using Sildenafil to avoid potentially serious effects on their cardiovascular system.

Penile Deformities: Sildenafil is not recommended for individuals with penile deformities.

Rare Inherited Eye Diseases: Individuals with rare inherited eye diseases such as retinitis pigmentosa should avoid using Sildenafil.

Hypersensitivity to Sildenafil or Nitrates: Those who have a known hypersensitivity to Sildenafil or who have received treatment with medications containing nitrates should not use Sildenafil.

Age Restriction: Sildenafil is not recommended for individuals under the age of 18.

Stomach Ulcer or Bleeding Problems: Individuals with a history of stomach ulcers or bleeding problems, such as hemophilia, should avoid using Sildenafil.

Pregnancy & Lactation

Acmegra 100mg Tablet is not recommended for use in women.

Precautions & Warnings
  • Hypotension: Acmegra 100mg Tablet may cause mild and short-lasting hypotension (decreased blood pressure levels) due to its ability to relax blood vessels. If you are taking medications to lower high blood pressure, be cautious when using Acmegra 100mg tablet.
  • Priapism: There's a risk of priapism, which is a painful erection lasting more than 4 hours, associated with Acmegra 100mg Tablet. Priapism can lead to damage to penile tissue and permanent loss of potency if not treated promptly. Use this tablet cautiously and seek immediate medical help if an erection lasts longer than 4 hours.
  • Loss of Hearing: Acmegra 100mg Tablet has been linked to sudden hearing loss. It could also cause ringing in the ears (tinnitus) or dizziness due to increased blood flow to the ears. If you experience any hearing issues after taking this medicine, seek medical attention promptly.
  • Surgery: Combining Acmegra 100mg Tablet with anesthesia and other surgical drugs can lead to a significant drop in blood pressure. If you're planning to undergo surgery, inform your doctor about your use of this medicine.
  • Use in Children: Acmegra 100mg Tablet is not recommended for individuals under 18 years of age due to a lack of established safety and efficacy data in this age group.
  • Counseling: Erectile dysfunction can have physical and psychological causes. Identifying the underlying cause is important for effective treatment. Counseling and therapy can enhance the benefits of Acmegra 100mg Tablet.
  • Use in Females: Acmegra 100mg Tablet is not intended for use in females.
  • Effect on Vision: Cases of visual impairment have been reported with Acmegra 100mg Tablet, especially when used alongside other PDE5 inhibitor medications. If you experience sudden vision loss, discontinue the medicine and seek medical attention immediately.
  • Effect on Bleeding: Use Acmegra 100mg Tablet cautiously if you have gastrointestinal bleeding or an active ulcer, as safety information is lacking in this context.
Storage Conditions

Store in a dry place, away from light and heat, out of reach of children.

Frequently Asked Questions (FAQ)

In some cases, Acmegra 100mg Tablet may cause sudden vision loss in one or both eyes. Stop taking Acmegra 100mg Tablet and consult your doctor immediately if you experience a sudden decrease or loss of vision.

Take Acmegra 100mg Tablet about 1 hour before you plan to have sex. Swallow the tablet whole with a glass of water. Inform your doctor if you feel the effect of Acmegra 100mg Tablet is too strong or too weak.

The effect of Acmegra 100mg Tablet can be observed within 30 to 60 minutes of taking the tablet.

Acmegra 100mg Tablet may remain in the body for 24 hours.

Acmegra 100mg Tablet may cause low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking; instead, lie down and get up slowly only when you feel better.
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Check our pricing section for Acmegra 100mg Tablet price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
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